BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 12595575)

  • 1. Gab2 tyrosine phosphorylation by a pleckstrin homology domain-independent mechanism: role in epidermal growth factor-induced mitogenesis.
    Kong M; Mounier C; Balbis A; Baquiran G; Posner BI
    Mol Endocrinol; 2003 May; 17(5):935-44. PubMed ID: 12595575
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Epidermal growth factor-induced DNA synthesis. Key role for Src phosphorylation of the docking protein Gab2.
    Kong M; Mounier C; Dumas V; Posner BI
    J Biol Chem; 2003 Feb; 278(8):5837-44. PubMed ID: 12464621
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epidermal growth factor-induced phosphatidylinositol 3-kinase activation and DNA synthesis. Identification of Grb2-associated binder 2 as the major mediator in rat hepatocytes.
    Kong M; Mounier C; Wu J; Posner BI
    J Biol Chem; 2000 Nov; 275(46):36035-42. PubMed ID: 10973965
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The involvement of the docking protein Gab1 in mitogenic signalling induced by EGF and HGF in rat hepatocytes.
    Aasrum M; Ødegård J; Sandnes D; Christoffersen T
    Biochim Biophys Acta; 2013 Dec; 1833(12):3286-3294. PubMed ID: 24126105
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase.
    Liu Y; Jenkins B; Shin JL; Rohrschneider LR
    Mol Cell Biol; 2001 May; 21(9):3047-56. PubMed ID: 11287610
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A comparison of epidermal growth factor receptor-mediated mitogenic signaling in response to transforming growth factor alpha and epidermal growth factor in cultured fetal rat hepatocytes.
    Lipeski LE; Boylan JM; Gruppuso PA
    Biochem Mol Biol Int; 1996 Aug; 39(5):975-83. PubMed ID: 8866014
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Roles of insulin receptor substrate-1 and Shc on insulin-like growth factor I receptor signaling in early passages of cultured human fibroblasts.
    Takahashi Y; Tobe K; Kadowaki H; Katsumata D; Fukushima Y; Yazaki Y; Akanuma Y; Kadowaki T
    Endocrinology; 1997 Feb; 138(2):741-50. PubMed ID: 9003010
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.
    Yu CF; Liu ZX; Cantley LG
    J Biol Chem; 2002 May; 277(22):19382-8. PubMed ID: 11896055
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional importance of amino-terminal domain of Shc for interaction with insulin and epidermal growth factor receptors in phosphorylation-independent manner.
    Sasaoka T; Ishihara H; Sawa T; Ishiki M; Morioka H; Imamura T; Usui I; Takata Y; Kobayashi M
    J Biol Chem; 1996 Aug; 271(33):20082-7. PubMed ID: 8702728
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway.
    Gu H; Maeda H; Moon JJ; Lord JD; Yoakim M; Nelson BH; Neel BG
    Mol Cell Biol; 2000 Oct; 20(19):7109-20. PubMed ID: 10982827
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tyrosine phosphorylation-dependent and -independent role of Shc in the regulation of IGF-1-induced mitogenesis and glycogen synthesis.
    Sasaoka T; Ishiki M; Wada T; Hori H; Hirai H; Haruta T; Ishihara H; Kobayashi M
    Endocrinology; 2001 Dec; 142(12):5226-35. PubMed ID: 11713219
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin growth factor-I and epidermal growth factor receptors recruit distinct upstream signaling molecules to enhance AKT activation in mammary epithelial cells.
    Fleming JM; Desury G; Polanco TA; Cohick WS
    Endocrinology; 2006 Dec; 147(12):6027-35. PubMed ID: 16990343
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ligation of CD28 stimulates the formation of a multimeric signaling complex involving grb-2-associated binder 2 (gab2), SRC homology phosphatase-2, and phosphatidylinositol 3-kinase: evidence that negative regulation of CD28 signaling requires the gab2 pleckstrin homology domain.
    Parry RV; Whittaker GC; Sims M; Edmead CE; Welham MJ; Ward SG
    J Immunol; 2006 Jan; 176(1):594-602. PubMed ID: 16365455
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Shc phosphotyrosine-binding domain dominantly interacts with epidermal growth factor receptors and mediates Ras activation in intact cells.
    Sakaguchi K; Okabayashi Y; Kido Y; Kimura S; Matsumura Y; Inushima K; Kasuga M
    Mol Endocrinol; 1998 Apr; 12(4):536-43. PubMed ID: 9544989
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Src-family tyrosine kinases in activation of ERK-1 and p85/p110-phosphatidylinositol 3-kinase by G/CCKB receptors.
    Daulhac L; Kowalski-Chauvel A; Pradayrol L; Vaysse N; Seva C
    J Biol Chem; 1999 Jul; 274(29):20657-63. PubMed ID: 10400698
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Formation of distinct signalling complexes involving phosphatidylinositol 3-kinase activity with stimulation of epidermal growth factor or insulin-like growth factor-I in human skin fibroblasts.
    Takahashi Y; Akanuma Y; Yazaki Y; Kadowaki T
    J Cell Physiol; 1999 Jan; 178(1):69-75. PubMed ID: 9886492
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of the Src homology 2 (SH2) domain and C-terminus tyrosine phosphorylation sites of SH2-containing inositol phosphatase (SHIP) in the regulation of insulin-induced mitogenesis.
    Wada T; Sasaoka T; Ishiki M; Hori H; Haruta T; Ishihara H; Kobayashi M
    Endocrinology; 1999 Oct; 140(10):4585-94. PubMed ID: 10499514
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential utilization of ShcA tyrosine residues and functional domains in the transduction of epidermal growth factor-induced mitogen-activated protein kinase activation in 293T cells and nerve growth factor-induced neurite outgrowth in PC12 cells. Identification of a new Grb2.Sos1 binding site.
    Thomas D; Bradshaw RA
    J Biol Chem; 1997 Aug; 272(35):22293-9. PubMed ID: 9268379
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells.
    Vacca F; Bagnato A; Catt KJ; Tecce R
    Cancer Res; 2000 Sep; 60(18):5310-7. PubMed ID: 11016663
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Formation of Shc/Grb2- and Crk adaptor complexes containing tyrosine phosphorylated Cbl upon stimulation of the B-cell antigen receptor.
    Smit L; van der Horst G; Borst J
    Oncogene; 1996 Jul; 13(2):381-9. PubMed ID: 8710377
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.