These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 12599478)

  • 1. Rational design of vitamin D3 analogues which selectively restore activity to a vitamin D receptor mutant associated with rickets.
    Swann SL; Bergh JJ; Farach-Carson MC; Koh JT
    Org Lett; 2002 Oct; 4(22):3863-6. PubMed ID: 12599478
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-based design of selective agonists for a rickets-associated mutant of the vitamin d receptor.
    Swann SL; Bergh J; Farach-Carson MC; Ocasio CA; Koh JT
    J Am Chem Soc; 2002 Nov; 124(46):13795-805. PubMed ID: 12431109
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhanced coactivator binding and transcriptional activation of mutant vitamin D receptors from patients with hereditary 1,25-dihydroxyvitamin D-resistant rickets by phosphorylation and vitamin D analogs.
    Liu Y; Shen Q; Malloy PJ; Soliman E; Peng X; Kim S; Pike JW; Feldman D; Christakos S
    J Bone Miner Res; 2005 Sep; 20(9):1680-91. PubMed ID: 16059639
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hereditary 1,25-dihydroxyvitamin D resistant rickets due to a mutation causing multiple defects in vitamin D receptor function.
    Malloy PJ; Xu R; Peng L; Peleg S; Al-Ashwal A; Feldman D
    Endocrinology; 2004 Nov; 145(11):5106-14. PubMed ID: 15308610
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A unique insertion/substitution in helix H1 of the vitamin D receptor ligand binding domain in a patient with hereditary 1,25-dihydroxyvitamin D-resistant rickets.
    Malloy PJ; Xu R; Cattani A; Reyes mL; Feldman D
    J Bone Miner Res; 2004 Jun; 19(6):1018-24. PubMed ID: 15190891
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity.
    Verlinden L; Verstuyf A; Verboven C; Eelen G; De Ranter C; Gao LJ; Chen YJ; Murad I; Choi M; Yamamoto K; Yamada S; Van Haver D; Vandewalle M; De Clercq PJ; Bouillon R
    J Biol Chem; 2003 Sep; 278(37):35476-82. PubMed ID: 12829710
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vitamin D receptors from patients with resistance to 1,25-dihydroxyvitamin D3: point mutations confer reduced transactivation in response to ligand and impaired interaction with the retinoid X receptor heterodimeric partner.
    Whitfield GK; Selznick SH; Haussler CA; Hsieh JC; Galligan MA; Jurutka PW; Thompson PD; Lee SM; Zerwekh JE; Haussler MR
    Mol Endocrinol; 1996 Dec; 10(12):1617-31. PubMed ID: 8961271
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transcriptional activation of the wild-type and mutant vitamin D receptors by vitamin D3 analogs.
    Futawaka K; Tagami T; Fukuda Y; Koyama R; Nushida A; Nezu S; Yamamoto H; Imamoto M; Kasahara M; Moriyama K
    J Mol Endocrinol; 2016 Jul; 57(1):23-32. PubMed ID: 27154546
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The vitamin D hormone and its nuclear receptor: molecular actions and disease states.
    Haussler MR; Haussler CA; Jurutka PW; Thompson PD; Hsieh JC; Remus LS; Selznick SH; Whitfield GK
    J Endocrinol; 1997 Sep; 154 Suppl():S57-73. PubMed ID: 9379138
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel screening system for high-affinity ligand of heredity vitamin D-resistant rickets-associated vitamin D receptor mutant R274L using bioluminescent sensor.
    Mano H; Nishikawa M; Yasuda K; Ikushiro S; Saito N; Sawada D; Honzawa S; Takano M; Kittaka A; Sakaki T
    J Steroid Biochem Mol Biol; 2017 Mar; 167():61-66. PubMed ID: 27864003
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lymphocyte cell lines from vitamin D-dependent rickets type II show functional defects in the 1 alpha,25-dihydroxyvitamin D3 receptor.
    Koeffler HP; Bishop JE; Reichel H; Singer F; Nagler A; Tobler A; Walka M; Norman AW
    Mol Cell Endocrinol; 1990 Mar; 70(1):1-11. PubMed ID: 2160380
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hereditary vitamin D resistant rickets caused by a novel mutation in the vitamin D receptor that results in decreased affinity for hormone and cellular hyporesponsiveness.
    Malloy PJ; Eccleshall TR; Gross C; Van Maldergem L; Bouillon R; Feldman D
    J Clin Invest; 1997 Jan; 99(2):297-304. PubMed ID: 9005998
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Singly dehydroxylated A-ring analogues of 19-nor-1alpha,25-dihydroxyvitamin D3 and 19-nor-22-oxa-1alpha,25-dihydroxyvitamin D3: novel vitamin D3 analogues with potent transcriptional activity but extremely low affinity for vitamin D receptor.
    Okano T; Nakagawa K; Tsugawa N; Ozono K; Kubodera N; Osawa A; Terada M; Mikami K
    Biol Pharm Bull; 1998 Dec; 21(12):1300-5. PubMed ID: 9881643
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Two mutations causing vitamin D resistant rickets: modelling on the basis of steroid hormone receptor DNA-binding domain crystal structures.
    Rut AR; Hewison M; Kristjansson K; Luisi B; Hughes MR; O'Riordan JL
    Clin Endocrinol (Oxf); 1994 Nov; 41(5):581-90. PubMed ID: 7828346
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Robust osteogenic efficacy of 2α-heteroarylalkyl vitamin D analogue AH-1 in VDR (R270L) hereditary vitamin D-dependent rickets model rats.
    Nishikawa M; Murose N; Mano H; Yasuda K; Isogai Y; Kittaka A; Takano M; Ikushiro S; Sakaki T
    Sci Rep; 2022 Jul; 12(1):12517. PubMed ID: 35869242
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hereditary 1,25-dihydroxyvitamin D-resistant rickets due to an opal mutation causing premature termination of the vitamin D receptor.
    Zhu W; Malloy PJ; Delvin E; Chabot G; Feldman D
    J Bone Miner Res; 1998 Feb; 13(2):259-64. PubMed ID: 9495519
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 20-Cyclopropyl-cholecalciferol vitamin D3 analogs: a unique class of potent inhibitors of proliferation of human prostate, breast and myeloid leukemia cell lines.
    Koike M; Koshizuka K; Kawabata H; Yang R; Taub HE; Said J; Uskokovic M; Tsuruoka N; Koeffler HP
    Anticancer Res; 1999; 19(3A):1689-97. PubMed ID: 10470102
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tryptophan missense mutation in the ligand-binding domain of the vitamin D receptor causes severe resistance to 1,25-dihydroxyvitamin D.
    Nguyen TM; Adiceam P; Kottler ML; Guillozo H; Rizk-Rabin M; Brouillard F; Lagier P; Palix C; Garnier JM; Garabedian M
    J Bone Miner Res; 2002 Sep; 17(9):1728-37. PubMed ID: 12211444
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lipopolysaccharide negatively modulates vitamin D action by down-regulating expression of vitamin D-induced VDR in human monocytic THP-1 cells.
    Pramanik R; Asplin JR; Lindeman C; Favus MJ; Bai S; Coe FL
    Cell Immunol; 2004; 232(1-2):137-43. PubMed ID: 15876428
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of two novel 14-epivitamin D3 analogs with vitamin D3 receptor-retinoid X receptor heterodimers on vitamin D3 responsive elements.
    Verlinden L; Verstuyf A; Quack M; Van Camp M; Van Etten E; De Clercq P; Vandewalle M; Carlberg C; Bouillon R
    J Bone Miner Res; 2001 Apr; 16(4):625-38. PubMed ID: 11315990
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.