151 related articles for article (PubMed ID: 12603319)
1. Site-directed mutagenesis of a loop at the active site of E1 (alpha2beta2) of the pyruvate dehydrogenase complex. A possible common sequence motif.
Fries M; Chauhan HJ; Domingo GJ; Jung HI; Perham RN
Eur J Biochem; 2003 Mar; 270(5):861-70. PubMed ID: 12603319
[TBL] [Abstract][Full Text] [Related]
2. Reaction mechanism of the heterotetrameric (alpha2beta2) E1 component of 2-oxo acid dehydrogenase multienzyme complexes.
Fries M; Jung HI; Perham RN
Biochemistry; 2003 Jun; 42(23):6996-7002. PubMed ID: 12795594
[TBL] [Abstract][Full Text] [Related]
3. Sites of limited proteolysis in the pyruvate decarboxylase component of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus and their role in catalysis.
Chauhan HJ; Domingo GJ; Jung HI; Perham RN
Eur J Biochem; 2000 Dec; 267(24):7158-69. PubMed ID: 11106427
[TBL] [Abstract][Full Text] [Related]
4. Protein-protein interaction revealed by NMR T(2) relaxation experiments: the lipoyl domain and E1 component of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus.
Howard MJ; Chauhan HJ; Domingo GJ; Fuller C; Perham RN
J Mol Biol; 2000 Jan; 295(4):1023-37. PubMed ID: 10656808
[TBL] [Abstract][Full Text] [Related]
5. Prediction of the binding site on E1 in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus.
Jung HI; Perham RN
FEBS Lett; 2003 Dec; 555(2):405-10. PubMed ID: 14644451
[TBL] [Abstract][Full Text] [Related]
6. Structural dependence of post-translational modification and reductive acetylation of the lipoyl domain of the pyruvate dehydrogenase multienzyme complex.
Wallis NG; Perham RN
J Mol Biol; 1994 Feb; 236(1):209-16. PubMed ID: 8107106
[TBL] [Abstract][Full Text] [Related]
7. Structural determinants of post-translational modification and catalytic specificity for the lipoyl domains of the pyruvate dehydrogenase multienzyme complex of Escherichia coli.
Jones DD; Horne HJ; Reche PA; Perham RN
J Mol Biol; 2000 Jan; 295(2):289-306. PubMed ID: 10623527
[TBL] [Abstract][Full Text] [Related]
8. Cloning and sequence analysis of the genes encoding the alpha and beta subunits of the E1 component of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus.
Hawkins CF; Borges A; Perham RN
Eur J Biochem; 1990 Jul; 191(2):337-46. PubMed ID: 2200674
[TBL] [Abstract][Full Text] [Related]
9. Distinct modes of recognition of the lipoyl domain as substrate by the E1 and E3 components of the pyruvate dehydrogenase multienzyme complex.
Fries M; Stott KM; Reynolds S; Perham RN
J Mol Biol; 2007 Feb; 366(1):132-9. PubMed ID: 17157320
[TBL] [Abstract][Full Text] [Related]
10. Theoretical study of the catalytic mechanism of E1 subunit of pyruvate dehydrogenase multienzyme complex from Bacillus stearothermophilus.
Sheng X; Liu Y
Biochemistry; 2013 Nov; 52(45):8079-93. PubMed ID: 24171427
[TBL] [Abstract][Full Text] [Related]
11. Recognition of a surface loop of the lipoyl domain underlies substrate channelling in the pyruvate dehydrogenase multienzyme complex.
Wallis NG; Allen MD; Broadhurst RW; Lessard IA; Perham RN
J Mol Biol; 1996 Nov; 263(3):463-74. PubMed ID: 8918601
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of the Escherichia coli pyruvate dehydrogenase complex E1 subunit and its tyrosine 177 variants by thiamin 2-thiazolone and thiamin 2-thiothiazolone diphosphates. Evidence for reversible tight-binding inhibition.
Nemeria N; Yan Y; Zhang Z; Brown AM; Arjunan P; Furey W; Guest JR; Jordan F
J Biol Chem; 2001 Dec; 276(49):45969-78. PubMed ID: 11583990
[TBL] [Abstract][Full Text] [Related]
13. Phosphorylation of serine 264 impedes active site accessibility in the E1 component of the human pyruvate dehydrogenase multienzyme complex.
Seifert F; Ciszak E; Korotchkina L; Golbik R; Spinka M; Dominiak P; Sidhu S; Brauer J; Patel MS; Tittmann K
Biochemistry; 2007 May; 46(21):6277-87. PubMed ID: 17474719
[TBL] [Abstract][Full Text] [Related]
14. Amino-terminal residues 1-45 of the Escherichia coli pyruvate dehydrogenase complex E1 subunit interact with the E2 subunit and are required for activity of the complex but not for reductive acetylation of the E2 subunit.
Park YH; Wei W; Zhou L; Nemeria N; Jordan F
Biochemistry; 2004 Nov; 43(44):14037-46. PubMed ID: 15518552
[TBL] [Abstract][Full Text] [Related]
15. Amino acid sequence analysis of the lipoyl and peripheral subunit-binding domains in the lipoate acetyltransferase component of the pyruvate dehydrogenase complex from Bacillus stearothermophilus.
Packman LC; Borges A; Perham RN
Biochem J; 1988 May; 252(1):79-86. PubMed ID: 3421911
[TBL] [Abstract][Full Text] [Related]
16. Self-assembly and catalytic activity of the pyruvate dehydrogenase multienzyme complex from Bacillus stearothermophilus.
Domingo GJ; Chauhan HJ; Lessard IA; Fuller C; Perham RN
Eur J Biochem; 1999 Dec; 266(3):1136-46. PubMed ID: 10583411
[TBL] [Abstract][Full Text] [Related]
17. Competitive interaction of component enzymes with the peripheral subunit-binding domain of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus: kinetic analysis using surface plasmon resonance detection.
Lessard IA; Fuller C; Perham RN
Biochemistry; 1996 Dec; 35(51):16863-70. PubMed ID: 8988025
[TBL] [Abstract][Full Text] [Related]
18. Cloning and sequence analysis of the genes encoding the dihydrolipoamide acetyltransferase and dihydrolipoamide dehydrogenase components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus.
Borges A; Hawkins CF; Packman LC; Perham RN
Eur J Biochem; 1990 Nov; 194(1):95-102. PubMed ID: 2253629
[TBL] [Abstract][Full Text] [Related]
19. Characterization of point mutations in patients with pyruvate dehydrogenase deficiency: role of methionine-181, proline-188, and arginine-349 in the alpha subunit.
Tripatara A; Korotchkina LG; Patel MS
Arch Biochem Biophys; 1999 Jul; 367(1):39-50. PubMed ID: 10375397
[TBL] [Abstract][Full Text] [Related]
20. Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multienzyme complex.
Pei XY; Titman CM; Frank RA; Leeper FJ; Luisi BF
Structure; 2008 Dec; 16(12):1860-72. PubMed ID: 19081062
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
