286 related articles for article (PubMed ID: 12611900)
1. Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.
Maglich JM; Parks DJ; Moore LB; Collins JL; Goodwin B; Billin AN; Stoltz CA; Kliewer SA; Lambert MH; Willson TM; Moore JT
J Biol Chem; 2003 May; 278(19):17277-83. PubMed ID: 12611900
[TBL] [Abstract][Full Text] [Related]
2. Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.
Kanno Y; Tanuma N; Yazawa S; Zhao S; Inaba M; Nakamura S; Nemoto K; Inouye Y
Drug Metab Dispos; 2016 Aug; 44(8):1158-63. PubMed ID: 27197997
[TBL] [Abstract][Full Text] [Related]
3. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
Kandel BA; Thomas M; Winter S; Damm G; Seehofer D; Burk O; Schwab M; Zanger UM
Biochim Biophys Acta; 2016 Sep; 1859(9):1218-1227. PubMed ID: 26994748
[TBL] [Abstract][Full Text] [Related]
4. CITCO Directly Binds to and Activates Human Pregnane X Receptor.
Lin W; Bwayi M; Wu J; Li Y; Chai SC; Huber AD; Chen T
Mol Pharmacol; 2020 Mar; 97(3):180-190. PubMed ID: 31882411
[TBL] [Abstract][Full Text] [Related]
5. The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3).
Laurenzana EM; Chen T; Kannuswamy M; Sell BE; Strom SC; Li Y; Omiecinski CJ
Mol Pharmacol; 2012 Nov; 82(5):918-28. PubMed ID: 22896671
[TBL] [Abstract][Full Text] [Related]
6. Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor.
de Boussac H; Gondeau C; Briolotti P; Duret C; Treindl F; Römer M; Fabre JM; Herrero A; Ramos J; Maurel P; Templin M; Gerbal-Chaloin S; Daujat-Chavanieu M
Drug Metab Dispos; 2018 Mar; 46(3):223-236. PubMed ID: 29269410
[TBL] [Abstract][Full Text] [Related]
7. Hepatic expression of thyroid hormone-responsive spot 14 protein is regulated by constitutive androstane receptor (NR1I3).
Breuker C; Moreau A; Lakhal L; Tamasi V; Parmentier Y; Meyer U; Maurel P; Lumbroso S; Vilarem MJ; Pascussi JM
Endocrinology; 2010 Apr; 151(4):1653-61. PubMed ID: 20185760
[TBL] [Abstract][Full Text] [Related]
8. Metformin represses drug-induced expression of CYP2B6 by modulating the constitutive androstane receptor signaling.
Yang H; Garzel B; Heyward S; Moeller T; Shapiro P; Wang H
Mol Pharmacol; 2014 Feb; 85(2):249-60. PubMed ID: 24252946
[TBL] [Abstract][Full Text] [Related]
9. Activation of the Constitutive Androstane Receptor Increases the Therapeutic Index of CHOP in Lymphoma Treatment.
Hedrich WD; Xiao J; Heyward S; Zhang Y; Zhang J; Baer MR; Hassan HE; Wang H
Mol Cancer Ther; 2016 Mar; 15(3):392-401. PubMed ID: 26823489
[TBL] [Abstract][Full Text] [Related]
10. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
[TBL] [Abstract][Full Text] [Related]
11. Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.
Ferguson SS; Chen Y; LeCluyse EL; Negishi M; Goldstein JA
Mol Pharmacol; 2005 Sep; 68(3):747-57. PubMed ID: 15933212
[TBL] [Abstract][Full Text] [Related]
12. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
Sahi J; Shord SS; Lindley C; Ferguson S; LeCluyse EL
J Biochem Mol Toxicol; 2009; 23(1):43-58. PubMed ID: 19202563
[TBL] [Abstract][Full Text] [Related]
13. Constitutive androstane receptor upregulates Abcb1 and Abcg2 at the blood-brain barrier after CITCO activation.
Lemmen J; Tozakidis IE; Bele P; Galla HJ
Brain Res; 2013 Mar; 1501():68-80. PubMed ID: 23340159
[TBL] [Abstract][Full Text] [Related]
14. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
15. Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors.
Paul KB; Thompson JT; Simmons SO; Vanden Heuvel JP; Crofton KM
Toxicol In Vitro; 2013 Oct; 27(7):2049-60. PubMed ID: 23899473
[TBL] [Abstract][Full Text] [Related]
16. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
Maglich JM; Stoltz CM; Goodwin B; Hawkins-Brown D; Moore JT; Kliewer SA
Mol Pharmacol; 2002 Sep; 62(3):638-46. PubMed ID: 12181440
[TBL] [Abstract][Full Text] [Related]
17. The Use of the LanthaScreen TR-FRET CAR Coactivator Assay in the Characterization of Constitutive Androstane Receptor (CAR) Inverse Agonists.
Carazo A; Pávek P
Sensors (Basel); 2015 Apr; 15(4):9265-76. PubMed ID: 25905697
[TBL] [Abstract][Full Text] [Related]
18. 2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists.
Smutny T; Nova A; Drechslerová M; Carazo A; Hyrsova L; Hrušková ZR; Kuneš J; Pour M; Špulák M; Pavek P
J Med Chem; 2016 May; 59(10):4601-10. PubMed ID: 27145071
[TBL] [Abstract][Full Text] [Related]
19. Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes.
Sueyoshi T; Li L; Wang H; Moore R; Kodavanti PR; Lehmler HJ; Negishi M; Birnbaum LS
Toxicol Sci; 2014 Feb; 137(2):292-302. PubMed ID: 24218150
[TBL] [Abstract][Full Text] [Related]
20. Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-
Mejdrová I; Dušek J; Škach K; Stefela A; Skoda J; Chalupský K; Dohnalová K; Pavkova I; Kronenberger T; Rashidian A; Smutná L; Duchoslav V; Smutny T; Pávek P; Nencka R
J Med Chem; 2023 Feb; 66(4):2422-2456. PubMed ID: 36756805
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]