BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 12615729)

  • 1. Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model.
    Ding H; Shannon P; Lau N; Wu X; Roncari L; Baldwin RL; Takebayashi H; Nagy A; Gutmann DH; Guha A
    Cancer Res; 2003 Mar; 63(5):1106-13. PubMed ID: 12615729
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas.
    Ding H; Roncari L; Shannon P; Wu X; Lau N; Karaskova J; Gutmann DH; Squire JA; Nagy A; Guha A
    Cancer Res; 2001 May; 61(9):3826-36. PubMed ID: 11325859
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin carcinogenesis.
    Casanova ML; Larcher F; Casanova B; Murillas R; Fernández-Aceñero MJ; Villanueva C; Martínez-Palacio J; Ullrich A; Conti CJ; Jorcano JL
    Cancer Res; 2002 Jun; 62(12):3402-7. PubMed ID: 12067982
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice.
    Weissenberger J; Steinbach JP; Malin G; Spada S; Rülicke T; Aguzzi A
    Oncogene; 1997 May; 14(17):2005-13. PubMed ID: 9160879
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Assessment of 1p/19q status by fluorescence in situ hybridization assay: A comparative study in oligodendroglial, mixed oligoastrocytic and astrocytic tumors.
    Shukla B; Agarwal S; Suri V; Pathak P; Sharma MC; Gupta D; Sharma BS; Suri A; Halder A; Sarkar C
    Neurol India; 2009; 57(5):559-66. PubMed ID: 19934553
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Astrocyte-specific expression of CDK4 is not sufficient for tumor formation, but cooperates with p53 heterozygosity to provide a growth advantage for astrocytes in vivo.
    Huang ZY; Baldwin RL; Hedrick NM; Gutmann DH
    Oncogene; 2002 Feb; 21(9):1325-34. PubMed ID: 11857076
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo.
    Dai C; Celestino JC; Okada Y; Louis DN; Fuller GN; Holland EC
    Genes Dev; 2001 Aug; 15(15):1913-25. PubMed ID: 11485986
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging.
    Su W; Xing R; Guha A; Gutmann DH; Sherman LS
    Glia; 2007 May; 55(7):723-33. PubMed ID: 17348023
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genetic determinants of malignancy in a mouse model for oligodendroglioma.
    Weiss WA; Burns MJ; Hackett C; Aldape K; Hill JR; Kuriyama H; Kuriyama N; Milshteyn N; Roberts T; Wendland MF; DePinho R; Israel MA
    Cancer Res; 2003 Apr; 63(7):1589-95. PubMed ID: 12670909
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras.
    Dlugosz AA; Hansen L; Cheng C; Alexander N; Denning MF; Threadgill DW; Magnuson T; Coffey RJ; Yuspa SH
    Cancer Res; 1997 Aug; 57(15):3180-8. PubMed ID: 9242447
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Astrocytes give rise to oligodendrogliomas and astrocytomas after gene transfer of polyoma virus middle T antigen in vivo.
    Holland EC; Li Y; Celestino J; Dai C; Schaefer L; Sawaya RA; Fuller GN
    Am J Pathol; 2000 Sep; 157(3):1031-7. PubMed ID: 10980141
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Brain tumors in S100beta-v-erbB transgenic rats.
    Ohgaki H; Kita D; Favereaux A; Huang H; Homma T; Dessen P; Weiss WA; Kleihues P; Heppner FL
    J Neuropathol Exp Neurol; 2006 Dec; 65(12):1111-7. PubMed ID: 17146284
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transgenic coexpression of v-Ha-ras and transforming growth factor alpha increases epidermal hyperproliferation and tumorigenesis and predisposes to malignant conversion via endogenous c-Ha-ras activation.
    Wang XJ; Greenhalgh DA; Roop DR
    Mol Carcinog; 2000 Mar; 27(3):200-9. PubMed ID: 10708482
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Overexpression of epidermal growth factor receptor in urothelium elicits urothelial hyperplasia and promotes bladder tumor growth.
    Cheng J; Huang H; Zhang ZT; Shapiro E; Pellicer A; Sun TT; Wu XR
    Cancer Res; 2002 Jul; 62(14):4157-63. PubMed ID: 12124355
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transgenic mice provide genetic evidence that transforming growth factor alpha promotes skin tumorigenesis via H-ras-dependent and H-ras-independent pathways.
    Jhappan C; Takayama H; Dickson RB; Merlino G
    Cell Growth Differ; 1994 Apr; 5(4):385-94. PubMed ID: 8043512
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transformation of astrocytes in transgenic mice expressing SV40 T antigen under the transcriptional control of the glial fibrillary acidic protein promoter.
    Danks RA; Orian JM; Gonzales MF; Tan SS; Alexander B; Mikoshiba K; Kaye AH
    Cancer Res; 1995 Oct; 55(19):4302-10. PubMed ID: 7671240
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pathological and molecular progression of astrocytomas in a GFAP:12 V-Ha-Ras mouse astrocytoma model.
    Shannon P; Sabha N; Lau N; Kamnasaran D; Gutmann DH; Guha A
    Am J Pathol; 2005 Sep; 167(3):859-67. PubMed ID: 16127163
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting.
    Sok JC; Coppelli FM; Thomas SM; Lango MN; Xi S; Hunt JL; Freilino ML; Graner MW; Wikstrand CJ; Bigner DD; Gooding WE; Furnari FB; Grandis JR
    Clin Cancer Res; 2006 Sep; 12(17):5064-73. PubMed ID: 16951222
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells.
    Ramnarain DB; Park S; Lee DY; Hatanpaa KJ; Scoggin SO; Otu H; Libermann TA; Raisanen JM; Ashfaq R; Wong ET; Wu J; Elliott R; Habib AA
    Cancer Res; 2006 Jan; 66(2):867-74. PubMed ID: 16424019
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Murine model of Alexander disease: analysis of GFAP aggregate formation and its pathological significance.
    Tanaka KF; Takebayashi H; Yamazaki Y; Ono K; Naruse M; Iwasato T; Itohara S; Kato H; Ikenaka K
    Glia; 2007 Apr; 55(6):617-31. PubMed ID: 17299771
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.