These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 12620083)

  • 1. Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy.
    Posner GH; Paik IH; Sur S; McRiner AJ; Borstnik K; Xie S; Shapiro TA
    J Med Chem; 2003 Mar; 46(6):1060-5. PubMed ID: 12620083
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anticancer and antimalarial efficacy and safety of artemisinin-derived trioxane dimers in rodents.
    Posner GH; McRiner AJ; Paik IH; Sur S; Borstnik K; Xie S; Shapiro TA; Alagbala A; Foster B
    J Med Chem; 2004 Feb; 47(5):1299-301. PubMed ID: 14971910
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antimalarial and antitumor evaluation of novel C-10 non-acetal dimers of 10beta-(2-hydroxyethyl)deoxoartemisinin.
    Jeyadevan JP; Bray PG; Chadwick J; Mercer AE; Byrne A; Ward SA; Park BK; Williams DP; Cosstick R; Davies J; Higson AP; Irving E; Posner GH; O'Neill PM
    J Med Chem; 2004 Feb; 47(5):1290-8. PubMed ID: 14971909
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of extraordinarily potent C-10 carba artemisinin dimers against P. falciparum malaria parasites and HL-60 cancer cells.
    Chadwick J; Mercer AE; Park BK; Cosstick R; O'Neill PM
    Bioorg Med Chem; 2009 Feb; 17(3):1325-38. PubMed ID: 19136263
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Malaria-infected mice are cured by oral administration of new artemisinin derivatives.
    Posner GH; Chang W; Hess L; Woodard L; Sinishtaj S; Usera AR; Maio W; Rosenthal AS; Kalinda AS; D'Angelo JG; Petersen KS; Stohler R; Chollet J; Santo-Tomas J; Snyder C; Rottmann M; Wittlin S; Brun R; Shapiro TA
    J Med Chem; 2008 Feb; 51(4):1035-42. PubMed ID: 18232653
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Second generation, orally active, antimalarial, artemisinin-derived trioxane dimers with high stability, efficacy, and anticancer activity.
    Paik IH; Xie S; Shapiro TA; Labonte T; Narducci Sarjeant AA; Baege AC; Posner GH
    J Med Chem; 2006 May; 49(9):2731-4. PubMed ID: 16640333
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fluoroartemisinin: trifluoromethyl analogues of artemether and artesunate.
    Magueur G; Crousse B; Charneau S; Grellier P; Bégué JP; Bonnet-Delpon D
    J Med Chem; 2004 May; 47(10):2694-9. PubMed ID: 15115411
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antitumor activity of novel deoxoartemisinin monomers, dimers, and trimer.
    Jung M; Lee S; Ham J; Lee K; Kim H; Kim SK
    J Med Chem; 2003 Mar; 46(6):987-94. PubMed ID: 12620075
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antimalarial, antiproliferative, and antitumor activities of artemisinin-derived, chemically robust, trioxane dimers.
    Posner GH; Ploypradith P; Parker MH; O'Dowd H; Woo SH; Northrop J; Krasavin M; Dolan P; Kensler TW; Xie S; Shapiro TA
    J Med Chem; 1999 Oct; 42(21):4275-80. PubMed ID: 10543871
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New orally active derivatives of artemisinin with high efficacy against multidrug-resistant malaria in mice.
    Singh C; Chaudhary S; Puri SK
    J Med Chem; 2006 Nov; 49(24):7227-33. PubMed ID: 17125275
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents.
    Chaturvedi D; Goswami A; Saikia PP; Barua NC; Rao PG
    Chem Soc Rev; 2010 Feb; 39(2):435-54. PubMed ID: 20111769
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumour and antimalarial activity of artemisinin-acridine hybrids.
    Jones M; Mercer AE; Stocks PA; La Pensée LJ; Cosstick R; Park BK; Kennedy ME; Piantanida I; Ward SA; Davies J; Bray PG; Rawe SL; Baird J; Charidza T; Janneh O; O'Neill PM
    Bioorg Med Chem Lett; 2009 Apr; 19(7):2033-7. PubMed ID: 19249201
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity.
    Galal AM; Gul W; Slade D; Ross SA; Feng S; Hollingshead MG; Alley MC; Kaur G; ElSohly MA
    Bioorg Med Chem; 2009 Jan; 17(2):741-51. PubMed ID: 19084416
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antimalarial activities of (+)-deoxoartemisitene and its novel C-11, 13 derivatives.
    Jung M; Lee K; Jung H; Kendrick H; Yardley V; Croft SL
    Bioorg Med Chem Lett; 2004 Apr; 14(8):2001-3. PubMed ID: 15050646
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Malaria-infected mice are cured by a single dose of novel artemisinin derivatives.
    Posner GH; Paik IH; Chang W; Borstnik K; Sinishtaj S; Rosenthal AS; Shapiro TA
    J Med Chem; 2007 May; 50(10):2516-9. PubMed ID: 17439113
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: implications for the molecular mechanism of action of the artemisinins.
    O'Neill PM; Rawe SL; Borstnik K; Miller A; Ward SA; Bray PG; Davies J; Oh CH; Posner GH
    Chembiochem; 2005 Nov; 6(11):2048-54. PubMed ID: 16222725
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chemical stability of the peroxide bond enables diversified synthesis of potent tetraoxane antimalarials.
    Opsenica I; Opsenica D; Smith KS; Milhous WK; Solaja BA
    J Med Chem; 2008 Apr; 51(7):2261-6. PubMed ID: 18330976
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Convenient access both to highly antimalaria-active 10-arylaminoartemisinins, and to 10-alkyl ethers including artemether, arteether, and artelinate.
    Haynes RK; Chan HW; Ho WY; Ko CK; Gerena L; Kyle DE; Peters W; Robinson BL
    Chembiochem; 2005 Apr; 6(4):659-67. PubMed ID: 15812783
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deoxycholic acid-derived tetraoxane antimalarials and antiproliferatives(1).
    Terzić N; Opsenica D; Milić D; Tinant B; Smith KS; Milhous WK; Solaja BA
    J Med Chem; 2007 Oct; 50(21):5118-27. PubMed ID: 17887664
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.
    Pacorel B; Leung SC; Stachulski AV; Davies J; Vivas L; Lander H; Ward SA; Kaiser M; Brun R; O'Neill PM
    J Med Chem; 2010 Jan; 53(2):633-40. PubMed ID: 19957999
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.