BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 12620660)

  • 1. Synthesis of heteroaromatic analogues of (2-aryl-1-cyclopentenyl-1-alkylidene)-(arylmethyloxy)amine COX-2 inhibitors: effects on the inhibitory activity of the replacement of the cyclopentene central core with pyrazole, thiophene or isoxazole ring.
    Balsamo A; Coletta I; Guglielmotti A; Landolfi C; Mancini F; Martinelli A; Milanese C; Minutolo F; Nencetti S; Orlandini E; Pinza M; Rapposelli S; Rossello A
    Eur J Med Chem; 2003 Feb; 38(2):157-68. PubMed ID: 12620660
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and COX-2 inhibitory properties of N-phenyl- and N-benzyl-substituted amides of 2-(4-methylsulfonylphenyl)cyclopent-1-ene-1-carboxylic acid and of their pyrazole, thiophene and isoxazole analogs.
    Rapposelli S; Lapucci A; Minutolo F; Orlandini E; Ortore G; Pinza M; Balsamo A
    Farmaco; 2004 Jan; 59(1):25-31. PubMed ID: 14751313
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aryl-substituted methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: effects of some structural modifications on their biological properties.
    Balsamo A; Coletta I; Guglielmotti A; Landolfi C; Lapucci A; Mancini F; Milanese C; Minutolo F; Orlandini E; Ortore G; Pinza M; Rapposelli S
    Eur J Med Chem; 2002 Jul; 37(7):585-94. PubMed ID: 12126777
    [TBL] [Abstract][Full Text] [Related]  

  • 4. (E)-[2-(4-Methylsulphonylphenyl)-1-cyclopentenyl-1-methyliden](arylmethyloxy)amines. Methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: synthesis and biological properties.
    Balsamo A; Coletta I; Domiano P; Guglielmotti A; Landolfi C; Mancini F; Milanese C; Orlandini E; Rapposelli S; Pinza M; Macchia B
    Eur J Med Chem; 2002 May; 37(5):391-8. PubMed ID: 12008053
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors.
    Ranatunge RR; Earl RA; Garvey DS; Janero DR; Letts LG; Martino AM; Murty MG; Richardson SK; Schwalb DJ; Young DV; Zemtseva IS
    Bioorg Med Chem Lett; 2004 Dec; 14(24):6049-52. PubMed ID: 15546727
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and selective cyclooxygenase-2 (COX-2) inhibitory activity of a series of novel bicyclic pyrazoles.
    Ranatunge RR; Garvey DS; Janero DR; Letts LG; Martino AM; Murty MG; Richardson SK; Young DV; Zemetseva IS
    Bioorg Med Chem; 2004 Mar; 12(6):1357-66. PubMed ID: 15018908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and cyclooxygenase-2 inhibiting property of 1,5-diarylpyrazoles with substituted benzenesulfonamide moiety as pharmacophore: Preparation of sodium salt for injectable formulation.
    Pal M; Madan M; Padakanti S; Pattabiraman VR; Kalleda S; Vanguri A; Mullangi R; Mamidi NV; Casturi SR; Malde A; Gopalakrishnan B; Yeleswarapu KR
    J Med Chem; 2003 Sep; 46(19):3975-84. PubMed ID: 12954051
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of 4,5-diaryl-1H-pyrazole-3-ol derivatives as potential COX-2 inhibitors.
    Patel MV; Bell R; Majest S; Henry R; Kolasa T
    J Org Chem; 2004 Oct; 69(21):7058-65. PubMed ID: 15471453
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 4-substituted 1,5-diarylpyrazole, analogues of celecoxib: synthesis and preliminary evaluation of biological properties.
    Menozzi G; Merello L; Fossa P; Mosti L; Piana A; Mattioli F
    Farmaco; 2003 Sep; 58(9):795-808. PubMed ID: 13679172
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel synthesis of 3,4-diarylisoxazole analogues of valdecoxib: reversal cyclooxygenase-2 selectivity by sulfonamide group removal.
    Di Nunno L; Vitale P; Scilimati A; Tacconelli S; Patrignani P
    J Med Chem; 2004 Sep; 47(20):4881-90. PubMed ID: 15369392
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Diarylheterocycle core ring features effect in selective COX-1 inhibition.
    Perrone MG; Vitale P; Malerba P; Altomare A; Rizzi R; Lavecchia A; Di Giovanni C; Novellino E; Scilimati A
    ChemMedChem; 2012 Apr; 7(4):629-41. PubMed ID: 22278975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and selective cyclooxygenase-2 inhibitory activity of a series of novel, nitric oxide donor-containing pyrazoles.
    Ranatunge RR; Augustyniak M; Bandarage UK; Earl RA; Ellis JL; Garvey DS; Janero DR; Letts LG; Martino AM; Murty MG; Richardson SK; Schroeder JD; Shumway MJ; Tam SW; Trocha AM; Young DV
    J Med Chem; 2004 Apr; 47(9):2180-93. PubMed ID: 15084117
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of cyclooxygenase-2 (COX-2) inhibitors on prostate cancer cell proliferation.
    Srinath P; Rao PN; Knaus EE; Suresh MR
    Anticancer Res; 2003; 23(5A):3923-8. PubMed ID: 14666698
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2.
    Sui Z; Guan J; Ferro MP; McCoy K; Wachter MP; Murray WV; Singer M; Steber M; Ritchie DM; Argentieri DC
    Bioorg Med Chem Lett; 2000 Mar; 10(6):601-4. PubMed ID: 10741562
    [TBL] [Abstract][Full Text] [Related]  

  • 15. QSAR analysis of some fused pyrazoles as selective cyclooxygenase-2 inhibitors: a Hansch approach.
    Prasanna S; Manivannan E; Chaturvedi SC
    Arch Pharm (Weinheim); 2004 Aug; 337(8):440-4. PubMed ID: 15293263
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors.
    Kalgutkar AS; Marnett AB; Crews BC; Remmel RP; Marnett LJ
    J Med Chem; 2000 Jul; 43(15):2860-70. PubMed ID: 10956194
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 4-Aryl/cycloalkyl-5-phenyloxazole derivatives as selective COX-2 inhibitors.
    Hashimoto H; Maeda K; Ozawa K; Haruta J; Wakitani K
    Bioorg Med Chem Lett; 2002 Jan; 12(1):65-8. PubMed ID: 11738574
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Three-dimensional quantitative structure-activity relationships of cyclo-oxygenase-2 (COX-2) inhibitors: a comparative molecular field analysis.
    Chavatte P; Yous S; Marot C; Baurin N; Lesieur D
    J Med Chem; 2001 Sep; 44(20):3223-30. PubMed ID: 11563921
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thalidomide and its analogues as cyclooxygenase inhibitors.
    Noguchi T; Shimazawa R; Nagasawa K; Hashimoto Y
    Bioorg Med Chem Lett; 2002 Apr; 12(7):1043-6. PubMed ID: 11909713
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The pyrrole moiety as a template for COX-1/COX-2 inhibitors.
    Dannhardt G; Kiefer W; Krämer G; Maehrlein S; Nowe U; Fiebich B
    Eur J Med Chem; 2000 May; 35(5):499-510. PubMed ID: 10889329
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.