These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 12628654)

  • 1. Novel B-ring modified allocolchicinoids of the NCME series: design, synthesis, antimicrotubule activity and cytotoxicity.
    Bergemann S; Brecht R; Büttner F; Guénard D; Gust R; Seitz G; Stubbs MT; Thoret S
    Bioorg Med Chem; 2003 Apr; 11(7):1269-81. PubMed ID: 12628654
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Two novel series of allocolchicinoids with modified seven membered B-rings: design, synthesis, inhibition of tubulin assembly and cytotoxicity.
    Büttner F; Bergemann S; Guénard D; Gust R; Seitz G; Thoret S
    Bioorg Med Chem; 2005 May; 13(10):3497-511. PubMed ID: 15848763
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel allocolchicinoids with an eight membered B-ring: design, synthesis and inhibition of tubulin assembly.
    Brecht R; Seitz G; Guénard D; Thoret S
    Bioorg Med Chem; 2000 Mar; 8(3):557-62. PubMed ID: 10732972
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitumor agents. Part 215: antitubulin effects of cytotoxic B-ring modified allocolchicinoids.
    Han S; Hamel E; Bastow KF; McPhail AT; Brossi A; Lee KH
    Bioorg Med Chem Lett; 2002 Oct; 12(20):2851-3. PubMed ID: 12270161
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antitumor agents. 139. Synthesis and biological evaluation of thiocolchicine analogs 5,6-dihydro-6(S)-(acyloxy)- and 5,6-dihydro-6(S)-[(aroyloxy)methyl]-1,2,3-trimethoxy-9-(methylthio)-8H- cyclohepta[a]naphthalen-8-ones as novel cytotoxic and antimitotic agents.
    Sun L; McPhail AT; Hamel E; Lin CM; Hastie SB; Chang JJ; Lee KH
    J Med Chem; 1993 Mar; 36(5):544-51. PubMed ID: 8496935
    [TBL] [Abstract][Full Text] [Related]  

  • 6. N-acetylcolchinol O-methyl ether and thiocolchicine, potent analogs of colchicine modified in the C ring. Evaluation of the mechanistic basis for their enhanced biological properties.
    Kang GJ; Getahun Z; Muzaffar A; Brossi A; Hamel E
    J Biol Chem; 1990 Jun; 265(18):10255-9. PubMed ID: 2191947
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of novel non-racemic indole-containing allocolchicinoids.
    Shchegravina ES; Maleev AA; Ignatov SK; Gracheva IA; Stein A; Schmalz HG; Gavryushin AE; Zubareva AA; Svirshchevskaya EV; Fedorov AY
    Eur J Med Chem; 2017 Dec; 141():51-60. PubMed ID: 29028531
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents.
    Shi Q; Verdier-Pinard P; Brossi A; Hamel E; McPhail AT; Lee KH
    J Med Chem; 1997 Mar; 40(6):961-6. PubMed ID: 9083485
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and tubulin-binding properties of new allocolchicinoids.
    Boyer FD; Dubois J; Thoret S; Dau ME; Hanna I
    Bioorg Chem; 2010 Aug; 38(4):149-58. PubMed ID: 20359734
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells.
    Verdier-Pinard P; Lai JY; Yoo HD; Yu J; Marquez B; Nagle DG; Nambu M; White JD; Falck JR; Gerwick WH; Day BW; Hamel E
    Mol Pharmacol; 1998 Jan; 53(1):62-76. PubMed ID: 9443933
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes.
    Majcher U; Urbaniak A; Maj E; Moshari M; Delgado M; Wietrzyk J; Bartl F; Chambers TC; Tuszynski JA; Huczyński A
    Bioorg Chem; 2018 Dec; 81():553-566. PubMed ID: 30248507
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Linkages in tubulin-colchicine functions: the role of the ring C (C') oxygens and ring B in the controls.
    Pérez-Ramírez B; Gorbunoff MJ; Timasheff SN
    Biochemistry; 1998 Feb; 37(6):1646-61. PubMed ID: 9484236
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and mechanism of action of novel pyrimidinyl pyrazole derivatives possessing antiproliferative activity.
    Ohki H; Hirotani K; Naito H; Ohsuki S; Minami M; Ejima A; Koiso Y; Hashimoto Y
    Bioorg Med Chem Lett; 2002 Nov; 12(21):3191-3. PubMed ID: 12372531
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of colchicine B-ring analogues tethered with halogenated benzyl moieties.
    Cosentino L; Redondo-Horcajo M; Zhao Y; Santos AR; Chowdury KF; Vinader V; Abdallah QM; Abdel-Rahman H; Fournier-Dit-Chabert J; Shnyder SD; Loadman PM; Fang WS; Díaz JF; Barasoain I; Burns PA; Pors K
    J Med Chem; 2012 Dec; 55(24):11062-6. PubMed ID: 23176628
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interaction of novel thiocolchicine analogs with the tubulin isoforms from bovine brain.
    Banerjee A; Kasmala LT; Hamel E; Sun L; Lee KH
    Biochem Biophys Res Commun; 1999 Jan; 254(2):334-7. PubMed ID: 9918839
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Exploring the size adaptability of the B ring binding zone of the colchicine site of tubulin with para-nitrogen substituted isocombretastatins.
    Jiménez C; Ellahioui Y; Álvarez R; Aramburu L; Riesco A; González M; Vicente A; Dahdouh A; Ibn Mansour A; Jiménez C; Martín D; Sarmiento RG; Medarde M; Caballero E; Peláez R
    Eur J Med Chem; 2015 Jul; 100():210-22. PubMed ID: 26092446
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability.
    Wang Z; Yang D; Mohanakrishnan AK; Fanwick PE; Nampoothiri P; Hamel E; Cushman M
    J Med Chem; 2000 Jun; 43(12):2419-29. PubMed ID: 10882369
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and antimicrotubule activity of combretatropone derivatives.
    Janik ME; Bane SL
    Bioorg Med Chem; 2002 Jun; 10(6):1895-903. PubMed ID: 11937347
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and cytostatic properties of polyfunctionalized furanoallocolchicinoids.
    Gracheva IA; Voitovich IV; Faerman VI; Sitnikov NS; Myrsikova EV; Schmalz HG; Svirshevskaya EV; Fedorov AY
    Eur J Med Chem; 2017 Jan; 126():432-443. PubMed ID: 27912174
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stoichiometric and substoichiometric inhibition of tubulin self-assembly by colchicine analogues.
    Perez-Ramirez B; Andreu JM; Gorbunoff MJ; Timasheff SN
    Biochemistry; 1996 Mar; 35(10):3277-85. PubMed ID: 8605164
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.