These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 12628925)

  • 1. GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction.
    Lufei C; Ma J; Huang G; Zhang T; Novotny-Diermayr V; Ong CT; Cao X
    EMBO J; 2003 Mar; 22(6):1325-35. PubMed ID: 12628925
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3.
    Zhang J; Yang J; Roy SK; Tininini S; Hu J; Bromberg JF; Poli V; Stark GR; Kalvakolanu DV
    Proc Natl Acad Sci U S A; 2003 Aug; 100(16):9342-7. PubMed ID: 12867595
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tumor-derived mutations in the gene associated with retinoid interferon-induced mortality (GRIM-19) disrupt its anti-signal transducer and activator of transcription 3 (STAT3) activity and promote oncogenesis.
    Nallar SC; Kalakonda S; Lindner DJ; Lorenz RR; Lamarre E; Weihua X; Kalvakolanu DV
    J Biol Chem; 2013 Mar; 288(11):7930-7941. PubMed ID: 23386605
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain.
    Tammineni P; Anugula C; Mohammed F; Anjaneyulu M; Larner AC; Sepuri NB
    J Biol Chem; 2013 Feb; 288(7):4723-32. PubMed ID: 23271731
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tumor-suppressive activity of the cell death activator GRIM-19 on a constitutively active signal transducer and activator of transcription 3.
    Kalakonda S; Nallar SC; Lindner DJ; Hu J; Reddy SP; Kalvakolanu DV
    Cancer Res; 2007 Jul; 67(13):6212-20. PubMed ID: 17616678
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Curcumin synergistically increases effects of β-interferon and retinoic acid on breast cancer cells in vitro and in vivo by up-regulation of GRIM-19 through STAT3-dependent and STAT3-independent pathways.
    Ren M; Wang Y; Wu X; Ge S; Wang B
    J Drug Target; 2017 Mar; 25(3):247-254. PubMed ID: 27677346
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tumor suppressive protein gene associated with retinoid-interferon-induced mortality (GRIM)-19 inhibits src-induced oncogenic transformation at multiple levels.
    Kalakonda S; Nallar SC; Gong P; Lindner DJ; Goldblum SE; Reddy SP; Kalvakolanu DV
    Am J Pathol; 2007 Oct; 171(4):1352-68. PubMed ID: 17823279
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of Stat3 activation by MEK kinase 1.
    Lim CP; Cao X
    J Biol Chem; 2001 Jun; 276(24):21004-11. PubMed ID: 11278353
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of monoclonal antibodies against GRIM-19, a novel IFN-beta and retinoic acid-activated regulator of cell death.
    Hu J; Angell JE; Zhang J; Ma X; Seo T; Raha A; Hayashi J; Choe J; Kalvakolanu DV
    J Interferon Cytokine Res; 2002 Oct; 22(10):1017-26. PubMed ID: 12433281
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The interaction of specific peptide aptamers with the DNA binding domain and the dimerization domain of the transcription factor Stat3 inhibits transactivation and induces apoptosis in tumor cells.
    Nagel-Wolfrum K; Buerger C; Wittig I; Butz K; Hoppe-Seyler F; Groner B
    Mol Cancer Res; 2004 Mar; 2(3):170-82. PubMed ID: 15037656
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis.
    Bowman T; Broome MA; Sinibaldi D; Wharton W; Pledger WJ; Sedivy JM; Irby R; Yeatman T; Courtneidge SA; Jove R
    Proc Natl Acad Sci U S A; 2001 Jun; 98(13):7319-24. PubMed ID: 11404481
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural exploration with AlphaFold2-generated STAT3α structure reveals selective elements in STAT3α-GRIM-19 interactions involved in negative regulation.
    Mishra S; Kumar S; Choudhuri KSR; Longkumer I; Koyyada P; Kharsyiemiong ET
    Sci Rep; 2021 Nov; 11(1):23145. PubMed ID: 34848745
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial GRIM-19 as a potential therapeutic target for STAT3-dependent carcinogenesis of gastric cancer.
    Huang Y; Yang M; Hu H; Zhao X; Bao L; Huang D; Song L; Li Y
    Oncotarget; 2016 Jul; 7(27):41404-41420. PubMed ID: 27167343
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1.
    Shen Y; Devgan G; Darnell JE; Bromberg JF
    Proc Natl Acad Sci U S A; 2001 Feb; 98(4):1543-8. PubMed ID: 11171987
    [TBL] [Abstract][Full Text] [Related]  

  • 15. GRIM-19 represses the proliferation and invasion of cutaneous squamous cell carcinoma cells associated with downregulation of STAT3 signaling.
    Wu N; Hui H; Cui L; Yang F
    Biomed Pharmacother; 2017 Nov; 95():1169-1176. PubMed ID: 28926927
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Grb2 regulates Stat3 activation negatively in epidermal growth factor signalling.
    Zhang T; Ma J; Cao X
    Biochem J; 2003 Dec; 376(Pt 2):457-64. PubMed ID: 14498832
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Plasmid-based Stat3-specific siRNA and GRIM-19 inhibit the growth of thyroid cancer cells in vitro and in vivo.
    Wang GM; Ren ZX; Wang PS; Su C; Zhang WX; Liu ZG; Zhang L; Zhao XJ; Chen G
    Oncol Rep; 2014 Aug; 32(2):573-80. PubMed ID: 24899100
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Overexpression of GRIM-19 in cancer cells suppresses STAT3-mediated signal transduction and cancer growth.
    Okamoto T; Inozume T; Mitsui H; Kanzaki M; Harada K; Shibagaki N; Shimada S
    Mol Cancer Ther; 2010 Aug; 9(8):2333-43. PubMed ID: 20682646
    [TBL] [Abstract][Full Text] [Related]  

  • 19.
    Cao F; Zhang Q; Chen W; Zheng F; Ran Q; He Y; Gao Y; Yao S
    Biosci Rep; 2017 Dec; 37(6):. PubMed ID: 29074558
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Correlations of GRIM-19 and its target gene product STAT3 to malignancy of human colorectal carcinoma].
    Gong LB; Luo XL; Liu SY; Tao DD; Gong JP; Hu JB
    Ai Zheng; 2007 Jul; 26(7):683-7. PubMed ID: 17626740
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.