These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

402 related articles for article (PubMed ID: 12629051)

  • 1. Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis.
    Metkar SS; Wang B; Ebbs ML; Kim JH; Lee YJ; Raja SM; Froelich CJ
    J Cell Biol; 2003 Mar; 160(6):875-85. PubMed ID: 12629051
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells.
    Wang GQ; Wieckowski E; Goldstein LA; Gastman BR; Rabinovitz A; Gambotto A; Li S; Fang B; Yin XM; Rabinowich H
    J Exp Med; 2001 Nov; 194(9):1325-37. PubMed ID: 11696597
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional dissociation of DeltaPsim and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis.
    Waterhouse NJ; Sedelies KA; Sutton VR; Pinkoski MJ; Thia KY; Johnstone R; Bird PI; Green DR; Trapani JA
    Cell Death Differ; 2006 Apr; 13(4):607-18. PubMed ID: 16167065
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
    Han J; Goldstein LA; Gastman BR; Rabinovitz A; Rabinowich H
    J Biol Chem; 2005 Apr; 280(16):16383-92. PubMed ID: 15713684
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
    Cheng EH; Wei MC; Weiler S; Flavell RA; Mak TW; Lindsten T; Korsmeyer SJ
    Mol Cell; 2001 Sep; 8(3):705-11. PubMed ID: 11583631
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.
    Sutton VR; Davis JE; Cancilla M; Johnstone RW; Ruefli AA; Sedelies K; Browne KA; Trapani JA
    J Exp Med; 2000 Nov; 192(10):1403-14. PubMed ID: 11085743
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway.
    Oh SH; Lee BH; Lim SC
    Biochem Pharmacol; 2004 Nov; 68(9):1845-55. PubMed ID: 15450950
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis.
    Perkins CL; Fang G; Kim CN; Bhalla KN
    Cancer Res; 2000 Mar; 60(6):1645-53. PubMed ID: 10749135
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis.
    Engels IH; Stepczynska A; Stroh C; Lauber K; Berg C; Schwenzer R; Wajant H; Jänicke RU; Porter AG; Belka C; Gregor M; Schulze-Osthoff K; Wesselborg S
    Oncogene; 2000 Sep; 19(40):4563-73. PubMed ID: 11030145
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.
    Heibein JA; Goping IS; Barry M; Pinkoski MJ; Shore GC; Green DR; Bleackley RC
    J Exp Med; 2000 Nov; 192(10):1391-402. PubMed ID: 11085742
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis.
    Belka C; Rudner J; Wesselborg S; Stepczynska A; Marini P; Lepple-Wienhues A; Faltin H; Bamberg M; Budach W; Schulze-Osthoff K
    Oncogene; 2000 Feb; 19(9):1181-90. PubMed ID: 10713706
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Granzyme B-mediated death of pancreatic beta-cells requires the proapoptotic BH3-only molecule bid.
    Estella E; McKenzie MD; Catterall T; Sutton VR; Bird PI; Trapani JA; Kay TW; Thomas HE
    Diabetes; 2006 Aug; 55(8):2212-9. PubMed ID: 16873683
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events.
    Han J; Goldstein LA; Gastman BR; Froelich CJ; Yin XM; Rabinowich H
    J Biol Chem; 2004 May; 279(21):22020-9. PubMed ID: 15014070
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Trail-induced apoptosis in Type I leukemic cells is not enhanced by overexpression of bax.
    Jia L; Patwari Y; Kelsey SM; Newland AC
    Biochem Biophys Res Commun; 2001 May; 283(5):1037-45. PubMed ID: 11355877
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.
    Yang X; Stennicke HR; Wang B; Green DR; Jänicke RU; Srinivasan A; Seth P; Salvesen GS; Froelich CJ
    J Biol Chem; 1998 Dec; 273(51):34278-83. PubMed ID: 9852092
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Granzyme H induces cell death primarily via a Bcl-2-sensitive mitochondrial cell death pathway that does not require direct Bid activation.
    Ewen CL; Kane KP; Bleackley RC
    Mol Immunol; 2013 Jul; 54(3-4):309-18. PubMed ID: 23352961
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K; Srinivasula SM; Alnemri ES; Thompson CB; Korsmeyer SJ; Bryant JL; Srivastava RK
    Cancer Res; 2003 Apr; 63(7):1712-21. PubMed ID: 12670926
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells.
    Hasenjäger A; Gillissen B; Müller A; Normand G; Hemmati PG; Schuler M; Dörken B; Daniel PT
    Oncogene; 2004 Jun; 23(26):4523-35. PubMed ID: 15064710
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Granzyme B-induced loss of mitochondrial inner membrane potential (Delta Psi m) and cytochrome c release are caspase independent.
    Heibein JA; Barry M; Motyka B; Bleackley RC
    J Immunol; 1999 Nov; 163(9):4683-93. PubMed ID: 10528165
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Adenovirus-mediated Bax overexpression for the induction of therapeutic apoptosis in prostate cancer.
    Li X; Marani M; Yu J; Nan B; Roth JA; Kagawa S; Fang B; Denner L; Marcelli M
    Cancer Res; 2001 Jan; 61(1):186-91. PubMed ID: 11196158
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.