311 related articles for article (PubMed ID: 12637530)
1. Critical role of the pleckstrin homology domain in Dbs signaling and growth regulation.
Fuentes EJ; Karnoub AE; Booden MA; Der CJ; Campbell SL
J Biol Chem; 2003 Jun; 278(23):21188-96. PubMed ID: 12637530
[TBL] [Abstract][Full Text] [Related]
2. Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation.
Rossman KL; Cheng L; Mahon GM; Rojas RJ; Snyder JT; Whitehead IP; Sondek J
J Biol Chem; 2003 May; 278(20):18393-400. PubMed ID: 12637522
[TBL] [Abstract][Full Text] [Related]
3. Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain.
Russo C; Gao Y; Mancini P; Vanni C; Porotto M; Falasca M; Torrisi MR; Zheng Y; Eva A
J Biol Chem; 2001 Jun; 276(22):19524-31. PubMed ID: 11278560
[TBL] [Abstract][Full Text] [Related]
4. Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation.
Whitehead IP; Lambert QT; Glaven JA; Abe K; Rossman KL; Mahon GM; Trzaskos JM; Kay R; Campbell SL; Der CJ
Mol Cell Biol; 1999 Nov; 19(11):7759-70. PubMed ID: 10523665
[TBL] [Abstract][Full Text] [Related]
5. Identification of Rho GTPase-dependent sites in the Dbl homology domain of oncogenic Dbl that are required for transformation.
Zhu K; Debreceni B; Li R; Zheng Y
J Biol Chem; 2000 Aug; 275(34):25993-6001. PubMed ID: 10854437
[TBL] [Abstract][Full Text] [Related]
6. Pleckstrin homology domain-mediated activation of the rho-specific guanine nucleotide exchange factor Dbs by Rac1.
Cheng L; Mahon GM; Kostenko EV; Whitehead IP
J Biol Chem; 2004 Mar; 279(13):12786-93. PubMed ID: 14701795
[TBL] [Abstract][Full Text] [Related]
7. Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation.
Booden MA; Campbell SL; Der CJ
Mol Cell Biol; 2002 Apr; 22(8):2487-97. PubMed ID: 11909943
[TBL] [Abstract][Full Text] [Related]
8. Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs.
Kostenko EV; Olabisi OO; Sahay S; Rodriguez PL; Whitehead IP
Mol Cell Biol; 2006 Dec; 26(23):8964-75. PubMed ID: 17000758
[TBL] [Abstract][Full Text] [Related]
9. Oligomerization of DH domain is essential for Dbl-induced transformation.
Zhu K; Debreceni B; Bi F; Zheng Y
Mol Cell Biol; 2001 Jan; 21(2):425-37. PubMed ID: 11134331
[TBL] [Abstract][Full Text] [Related]
10. Regulation of proto-Dbl by intracellular membrane targeting and protein stability.
Vanni C; Mancini P; Gao Y; Ottaviano C; Guo F; Salani B; Torrisi MR; Zheng Y; Eva A
J Biol Chem; 2002 May; 277(22):19745-53. PubMed ID: 11907027
[TBL] [Abstract][Full Text] [Related]
11. Role of the pleckstrin homology domain in intersectin-L Dbl homology domain activation of Cdc42 and signaling.
Pruitt WM; Karnoub AE; Rakauskas AC; Guipponi M; Antonarakis SE; Kurakin A; Kay BK; Sondek J; Siderovski DP; Der CJ
Biochim Biophys Acta; 2003 Apr; 1640(1):61-8. PubMed ID: 12676355
[TBL] [Abstract][Full Text] [Related]
12. Structure and mutagenesis of the Dbl homology domain.
Aghazadeh B; Zhu K; Kubiseski TJ; Liu GA; Pawson T; Zheng Y; Rosen MK
Nat Struct Biol; 1998 Dec; 5(12):1098-107. PubMed ID: 9846881
[TBL] [Abstract][Full Text] [Related]
13. A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
Rossman KL; Worthylake DK; Snyder JT; Siderovski DP; Campbell SL; Sondek J
EMBO J; 2002 Mar; 21(6):1315-26. PubMed ID: 11889037
[TBL] [Abstract][Full Text] [Related]
14. Oncogenic Dbl, Cdc42, and p21-activated kinase form a ternary signaling intermediate through the minimum interactive domains.
Wang L; Zhu K; Zheng Y
Biochemistry; 2004 Nov; 43(46):14584-93. PubMed ID: 15544329
[TBL] [Abstract][Full Text] [Related]
15. Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant.
Debreceni B; Gao Y; Guo F; Zhu K; Jia B; Zheng Y
J Biol Chem; 2004 Jan; 279(5):3777-86. PubMed ID: 14597635
[TBL] [Abstract][Full Text] [Related]
16. RhoGEF specificity mutants implicate RhoA as a target for Dbs transforming activity.
Cheng L; Rossman KL; Mahon GM; Worthylake DK; Korus M; Sondek J; Whitehead IP
Mol Cell Biol; 2002 Oct; 22(19):6895-905. PubMed ID: 12215546
[TBL] [Abstract][Full Text] [Related]
17. Crystal structure of the DH/PH fragment of Dbs without bound GTPase.
Worthylake DK; Rossman KL; Sondek J
Structure; 2004 Jun; 12(6):1078-86. PubMed ID: 15274927
[TBL] [Abstract][Full Text] [Related]
18. DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA.
Mavrakis KJ; McKinlay KJ; Jones P; Sablitzky F
Exp Cell Res; 2004 Apr; 294(2):335-44. PubMed ID: 15023524
[TBL] [Abstract][Full Text] [Related]
19. Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
Kristelly R; Gao G; Tesmer JJ
J Biol Chem; 2004 Nov; 279(45):47352-62. PubMed ID: 15331592
[TBL] [Abstract][Full Text] [Related]
20. Autoinhibition mechanism of proto-Dbl.
Bi F; Debreceni B; Zhu K; Salani B; Eva A; Zheng Y
Mol Cell Biol; 2001 Mar; 21(5):1463-74. PubMed ID: 11238883
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]