BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

402 related articles for article (PubMed ID: 12637545)

  • 1. Chromium (VI) activates ataxia telangiectasia mutated (ATM) protein. Requirement of ATM for both apoptosis and recovery from terminal growth arrest.
    Ha L; Ceryak S; Patierno SR
    J Biol Chem; 2003 May; 278(20):17885-94. PubMed ID: 12637545
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of gamma-H2AX.
    Ha L; Ceryak S; Patierno SR
    Carcinogenesis; 2004 Nov; 25(11):2265-74. PubMed ID: 15284180
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner.
    Hirao A; Cheung A; Duncan G; Girard PM; Elia AJ; Wakeham A; Okada H; Sarkissian T; Wong JA; Sakai T; De Stanchina E; Bristow RG; Suda T; Lowe SW; Jeggo PA; Elledge SJ; Mak TW
    Mol Cell Biol; 2002 Sep; 22(18):6521-32. PubMed ID: 12192050
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Carcinogenic lead chromate induces DNA double-strand breaks in human lung cells.
    Xie H; Wise SS; Holmes AL; Xu B; Wakeman TP; Pelsue SC; Singh NP; Wise JP
    Mutat Res; 2005 Oct; 586(2):160-72. PubMed ID: 16112599
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The ATM-SMC1 pathway is essential for activation of the chromium[VI]-induced S-phase checkpoint.
    Wakeman TP; Kim WJ; Callens S; Chiu A; Brown KD; Xu B
    Mutat Res; 2004 Oct; 554(1-2):241-51. PubMed ID: 15450422
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanism of apoptosis and determination of cellular fate in chromium(VI)-exposed populations of telomerase-immortalized human fibroblasts.
    Pritchard DE; Ceryak S; Ha L; Fornsaglio JL; Hartman SK; O'Brien TJ; Patierno SR
    Cell Growth Differ; 2001 Oct; 12(10):487-96. PubMed ID: 11682460
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
    Kurz EU; Douglas P; Lees-Miller SP
    J Biol Chem; 2004 Dec; 279(51):53272-81. PubMed ID: 15489221
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of ataxia telangiectasia mutated by DNA strand break-inducing agents correlates closely with the number of DNA double strand breaks.
    Ismail IH; Nyström S; Nygren J; Hammarsten O
    J Biol Chem; 2005 Feb; 280(6):4649-55. PubMed ID: 15546858
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The radiomimetic enediyne C-1027 induces unusual DNA damage responses to double-strand breaks.
    Kennedy DR; Beerman TA
    Biochemistry; 2006 Mar; 45(11):3747-54. PubMed ID: 16533058
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis.
    Kurose A; Tanaka T; Huang X; Traganos F; Dai W; Darzynkiewicz Z
    Cytometry A; 2006 Apr; 69(4):212-21. PubMed ID: 16528719
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage.
    Helt CE; Cliby WA; Keng PC; Bambara RA; O'Reilly MA
    J Biol Chem; 2005 Jan; 280(2):1186-92. PubMed ID: 15533933
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ataxia telangiectasia-mutated-Rad3-related DNA damage checkpoint signaling pathway triggered by hepatitis B virus infection.
    Zhao F; Hou NB; Yang XL; He X; Liu Y; Zhang YH; Wei CW; Song T; Li L; Ma QJ; Zhong H
    World J Gastroenterol; 2008 Oct; 14(40):6163-70. PubMed ID: 18985806
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection.
    Shirata N; Kudoh A; Daikoku T; Tatsumi Y; Fujita M; Kiyono T; Sugaya Y; Isomura H; Ishizaki K; Tsurumi T
    J Biol Chem; 2005 Aug; 280(34):30336-41. PubMed ID: 15964848
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.
    Tomimatsu N; Tahimic CG; Otsuki A; Burma S; Fukuhara A; Sato K; Shiota G; Oshimura M; Chen DJ; Kurimasa A
    J Biol Chem; 2007 Apr; 282(14):10138-45. PubMed ID: 17272272
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.
    Cerosaletti K; Concannon P
    J Biol Chem; 2004 Sep; 279(37):38813-9. PubMed ID: 15234984
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relationship between DNA double-strand break rejoining and cell survival after exposure to ionizing radiation in human fibroblast strains with differing ATM/p53 status: implications for evaluation of clinical radiosensitivity.
    Mirzayans R; Severin D; Murray D
    Int J Radiat Oncol Biol Phys; 2006 Dec; 66(5):1498-505. PubMed ID: 17126209
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.
    Kang J; Ferguson D; Song H; Bassing C; Eckersdorff M; Alt FW; Xu Y
    Mol Cell Biol; 2005 Jan; 25(2):661-70. PubMed ID: 15632067
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ATR regulates hexavalent chromium-induced S-phase checkpoint through phosphorylation of SMC1.
    Wakeman TP; Xu B
    Mutat Res; 2006 Nov; 610(1-2):14-20. PubMed ID: 16876463
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Contribution of the Atm protein to maintaining cellular homeostasis evidenced by continuous activation of the AP-1 pathway in Atm-deficient brains.
    Weizman N; Shiloh Y; Barzilai A
    J Biol Chem; 2003 Feb; 278(9):6741-7. PubMed ID: 12496286
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATM-Chk2-Cdc25A and ATM-p53-p21-pathways.
    Gaul L; Mandl-Weber S; Baumann P; Emmerich B; Schmidmaier R
    J Cancer Res Clin Oncol; 2008 Feb; 134(2):245-53. PubMed ID: 17653574
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.