BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 12641460)

  • 1. Binding of a photoaffinity analogue of glutathione to MRP1 (ABCC1) within two cytoplasmic regions (L0 and L1) as well as transmembrane domains 10-11 and 16-17.
    Karwatsky J; Daoud R; Cai J; Gros P; Georges E
    Biochemistry; 2003 Mar; 42(11):3286-94. PubMed ID: 12641460
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The leucotriene C4 binding sites in multidrug resistance protein 1 (ABCC1) include the first membrane multiple spanning domain.
    Karwatsky J; Leimanis M; Cai J; Gros P; Georges E
    Biochemistry; 2005 Jan; 44(1):340-51. PubMed ID: 15628876
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Drug binding domains of MRP1 (ABCC1) as revealed by photoaffinity labeling.
    Karwatsky JM; Georges E
    Curr Med Chem Anticancer Agents; 2004 Jan; 4(1):19-30. PubMed ID: 14754409
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Major photoaffinity drug binding sites in multidrug resistance protein 1 (MRP1) are within transmembrane domains 10-11 and 16-17.
    Daoud R; Julien M; Gros P; Georges E
    J Biol Chem; 2001 Apr; 276(15):12324-30. PubMed ID: 11152467
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3).
    Grant CE; Gao M; DeGorter MK; Cole SP; Deeley RG
    Drug Metab Dispos; 2008 Dec; 36(12):2571-81. PubMed ID: 18775981
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport.
    Rothnie A; Conseil G; Lau AY; Deeley RG; Cole SP
    Mol Pharmacol; 2008 Dec; 74(6):1630-40. PubMed ID: 18768387
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A positively charged amino acid proximal to the C-terminus of TM17 of MRP1 is indispensable for GSH-dependent binding of substrates and for transport of LTC4.
    Ren XQ; Furukawa T; Aoki S; Sumizawa T; Haraguchi M; Nakajima Y; Ikeda R; Kobayashi M; Akiyama S
    Biochemistry; 2002 Dec; 41(48):14132-40. PubMed ID: 12450376
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MRP1 mutated in the L0 region transports SN-38 but not leukotriene C4 or estradiol-17 (beta-D-glucuronate).
    Noguchi T; Ren XQ; Aoki S; Igarashi Y; Che XF; Nakajima Y; Takahashi H; Mitsuo R; Tsujikawa K; Sumizawa T; Haraguchi M; Kobayashi M; Goto S; Kanehisa M; Aikou T; Akiyama S; Furukawa T
    Biochem Pharmacol; 2005 Oct; 70(7):1056-65. PubMed ID: 16098482
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glutathione-dependent binding of a photoaffinity analog of agosterol A to the C-terminal half of human multidrug resistance protein.
    Ren XQ; Furukawa T; Aoki S; Nakajima T; Sumizawa T; Haraguchi M; Chen ZS; Kobayashi M; Akiyama S
    J Biol Chem; 2001 Jun; 276(25):23197-206. PubMed ID: 11301332
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas.
    Conseil G; Deeley RG; Cole SP
    Biochem Pharmacol; 2005 Feb; 69(3):451-61. PubMed ID: 15652236
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required.
    Leslie EM; Haimeur A; Waalkes MP
    J Biol Chem; 2004 Jul; 279(31):32700-8. PubMed ID: 15161912
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein.
    Qian YM; Qiu W; Gao M; Westlake CJ; Cole SP; Deeley RG
    J Biol Chem; 2001 Oct; 276(42):38636-44. PubMed ID: 11507101
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transmembrane helix 11 of multidrug resistance protein 1 (MRP1/ABCC1): identification of polar amino acids important for substrate specificity and binding of ATP at nucleotide binding domain 1.
    Zhang DW; Nunoya K; Vasa M; Gu HM; Theis A; Cole SP; Deeley RG
    Biochemistry; 2004 Jul; 43(29):9413-25. PubMed ID: 15260484
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1).
    Maeno K; Nakajima A; Conseil G; Rothnie A; Deeley RG; Cole SP
    Drug Metab Dispos; 2009 Jul; 37(7):1411-20. PubMed ID: 19398503
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of the binding of the tricyclic isoxazole photoaffinity label LY475776 to multidrug resistance associated protein 1 (MRP1) orthologs and several ATP- binding cassette (ABC) drug transporters.
    Dantzig AH; Shepard RL; Pratt SE; Tabas LB; Lander PA; Ma L; Paul DC; Williams DC; Peng SB; Slapak CA; Godinot N; Perry WL
    Biochem Pharmacol; 2004 Mar; 67(6):1111-21. PubMed ID: 15006547
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation.
    Ambadipudi R; Georges E
    Biochem Biophys Res Commun; 2017 Jan; 482(4):1001-1006. PubMed ID: 27908733
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain.
    Mao Q; Qiu W; Weigl KE; Lander PA; Tabas LB; Shepard RL; Dantzig AH; Deeley RG; Cole SP
    J Biol Chem; 2002 Aug; 277(32):28690-9. PubMed ID: 12034727
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Localization of the GSH-dependent photolabelling site of an agosterol A analog on human MRP1.
    Ren XQ; Furukawa T; Aoki S; Sumizawa T; Haraguchi M; Che XF; Kobayashi M; Akiyama S
    Br J Pharmacol; 2003 Apr; 138(8):1553-61. PubMed ID: 12721111
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Photolabeling of human and murine multidrug resistance protein 1 with the high affinity inhibitor [125I]LY475776 and azidophenacyl-[35S]glutathione.
    Qian YM; Grant CE; Westlake CJ; Zhang DW; Lander PA; Shepard RL; Dantzig AH; Cole SP; Deeley RG
    J Biol Chem; 2002 Sep; 277(38):35225-31. PubMed ID: 12138119
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of GSH in estrone sulfate binding and translocation by the multidrug resistance protein 1 (MRP1/ABCC1).
    Rothnie A; Callaghan R; Deeley RG; Cole SP
    J Biol Chem; 2006 May; 281(20):13906-14. PubMed ID: 16565074
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.