These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 12642383)

  • 1. Identification of the di-pyridyl ketone isonicotinoyl hydrazone (PKIH) analogues as potent iron chelators and anti-tumour agents.
    Becker EM; Lovejoy DB; Greer JM; Watts R; Richardson DR
    Br J Pharmacol; 2003 Mar; 138(5):819-30. PubMed ID: 12642383
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development of novel aroylhydrazone ligands for iron chelation therapy: 2-pyridylcarboxaldehyde isonicotinoyl hydrazone analogs.
    Becker E; Richardson DR
    J Lab Clin Med; 1999 Nov; 134(5):510-21. PubMed ID: 10560945
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation.
    Chaston TB; Watts RN; Yuan J; Richardson DR
    Clin Cancer Res; 2004 Nov; 10(21):7365-74. PubMed ID: 15534113
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protection against hydrogen peroxide-mediated cytotoxicity in Friedreich's ataxia fibroblasts using novel iron chelators of the 2-pyridylcarboxaldehyde isonicotinoyl hydrazone class.
    Lim CK; Kalinowski DS; Richardson DR
    Mol Pharmacol; 2008 Jul; 74(1):225-35. PubMed ID: 18424550
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and characterization of new iron chelators with anti-proliferative activity: structure-activity relationships of novel thiohydrazone analogues.
    Kalinowski DS; Sharpe PC; Bernhardt PV; Richardson DR
    J Med Chem; 2007 Nov; 50(24):6212-25. PubMed ID: 17963372
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents II: the mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone.
    Richardson DR; Milnes K
    Blood; 1997 Apr; 89(8):3025-38. PubMed ID: 9108424
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Unprecedented oxidation of a biologically active aroylhydrazone chelator catalysed by iron(III): serendipitous identification of diacylhydrazine ligands with high iron chelation efficacy.
    Bernhardt PV; Chin P; Richardson DR
    J Biol Inorg Chem; 2001 Oct; 6(8):801-9. PubMed ID: 11713687
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potent antimycobacterial activity of the pyridoxal isonicotinoyl hydrazone analog 2-pyridylcarboxaldehyde isonicotinoyl hydrazone: a lipophilic transport vehicle for isonicotinic acid hydrazide.
    Ellis S; Kalinowski DS; Leotta L; Huang ML; Jelfs P; Sintchenko V; Richardson DR; Triccas JA
    Mol Pharmacol; 2014 Feb; 85(2):269-78. PubMed ID: 24243647
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Complexes of cytotoxic chelators from the dipyridyl ketone isonicotinoyl hydrazone (HPKIH) analogues.
    Bernhardt PV; Mattsson J; Richardson DR
    Inorg Chem; 2006 Jan; 45(2):752-60. PubMed ID: 16411711
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.
    Chaston TB; Lovejoy DB; Watts RN; Richardson DR
    Clin Cancer Res; 2003 Jan; 9(1):402-14. PubMed ID: 12538494
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Methyl and ethyl ketone analogs of salicylaldehyde isonicotinoyl hydrazone: novel iron chelators with selective antiproliferative action.
    Macková E; Hrušková K; Bendová P; Vávrová A; Jansová H; Hašková P; Kovaříková P; Vávrová K; Simůnek T
    Chem Biol Interact; 2012 May; 197(2-3):69-79. PubMed ID: 22521999
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Future of toxicology--iron chelators and differing modes of action and toxicity: the changing face of iron chelation therapy.
    Kalinowski DS; Richardson DR
    Chem Res Toxicol; 2007 May; 20(5):715-20. PubMed ID: 17402750
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents III: the effect of the ligands on molecular targets involved in proliferation.
    Darnell G; Richardson DR
    Blood; 1999 Jul; 94(2):781-92. PubMed ID: 10397746
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationships of novel iron chelators for the treatment of iron overload disease: the methyl pyrazinylketone isonicotinoyl hydrazone series.
    Kalinowski DS; Sharpe PC; Bernhardt PV; Richardson DR
    J Med Chem; 2008 Jan; 51(2):331-44. PubMed ID: 18159922
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity relationships of novel salicylaldehyde isonicotinoyl hydrazone (SIH) analogs: iron chelation, anti-oxidant and cytotoxic properties.
    Potůčková E; Hrušková K; Bureš J; Kovaříková P; Špirková IA; Pravdíková K; Kolbabová L; Hergeselová T; Hašková P; Jansová H; Macháček M; Jirkovská A; Richardson V; Lane DJ; Kalinowski DS; Richardson DR; Vávrová K; Šimůnek T
    PLoS One; 2014; 9(11):e112059. PubMed ID: 25393531
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interactions of the pyridine-2-carboxaldehyde isonicotinoyl hydrazone class of chelators with iron and DNA: implications for toxicity in the treatment of iron overload disease.
    Chaston TB; Richardson DR
    J Biol Inorg Chem; 2003 Apr; 8(4):427-38. PubMed ID: 12761664
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytotoxic iron chelators: characterization of the structure, solution chemistry and redox activity of ligands and iron complexes of the di-2-pyridyl ketone isonicotinoyl hydrazone (HPKIH) analogues.
    Bernhardt PV; Caldwell LM; Chaston TB; Chin P; Richardson DR
    J Biol Inorg Chem; 2003 Nov; 8(8):866-80. PubMed ID: 14564555
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PCTH: a novel orally active chelator for the treatment of iron overload disease.
    Lovejoy DB; Kalinowski D; Bernhardt PV; Richardson DR
    Hemoglobin; 2006; 30(1):93-104. PubMed ID: 16540421
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.
    Kalinowski DS; Yu Y; Sharpe PC; Islam M; Liao YT; Lovejoy DB; Kumar N; Bernhardt PV; Richardson DR
    J Med Chem; 2007 Jul; 50(15):3716-29. PubMed ID: 17602603
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligands.
    Bernhardt PV; Wilson GJ; Sharpe PC; Kalinowski DS; Richardson DR
    J Biol Inorg Chem; 2008 Jan; 13(1):107-19. PubMed ID: 17899222
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.