These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
478 related articles for article (PubMed ID: 12642586)
1. Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins. Moreau C; Cartron PF; Hunt A; Meflah K; Green DR; Evan G; Vallette FM; Juin P J Biol Chem; 2003 May; 278(21):19426-35. PubMed ID: 12642586 [TBL] [Abstract][Full Text] [Related]
2. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner. Kazi A; Sun J; Doi K; Sung SS; Takahashi Y; Yin H; Rodriguez JM; Becerril J; Berndt N; Hamilton AD; Wang HG; Sebti SM J Biol Chem; 2011 Mar; 286(11):9382-92. PubMed ID: 21148306 [TBL] [Abstract][Full Text] [Related]
3. Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases. Holinger EP; Chittenden T; Lutz RJ J Biol Chem; 1999 May; 274(19):13298-304. PubMed ID: 10224090 [TBL] [Abstract][Full Text] [Related]
4. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax. Hockings C; Anwari K; Ninnis RL; Brouwer J; O'Hely M; Evangelista M; Hinds MG; Czabotar PE; Lee EF; Fairlie WD; Dewson G; Kluck RM Cell Death Dis; 2015 Apr; 6(4):e1735. PubMed ID: 25906158 [TBL] [Abstract][Full Text] [Related]
5. Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL. Yamaguchi H; Wang HG J Biol Chem; 2002 Nov; 277(44):41604-12. PubMed ID: 12198137 [TBL] [Abstract][Full Text] [Related]
6. Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions. Finnegan NM; Curtin JF; Prevost G; Morgan B; Cotter TG Br J Cancer; 2001 Jul; 85(1):115-21. PubMed ID: 11437412 [TBL] [Abstract][Full Text] [Related]
7. Peptides derived from BH3 domains of Bcl-2 family members: a comparative analysis of inhibition of Bcl-2, Bcl-x(L) and Bax oligomerization, induction of cytochrome c release, and activation of cell death. Shangary S; Johnson DE Biochemistry; 2002 Jul; 41(30):9485-95. PubMed ID: 12135371 [TBL] [Abstract][Full Text] [Related]
8. BH3 domains other than Bim and Bid can directly activate Bax/Bak. Du H; Wolf J; Schafer B; Moldoveanu T; Chipuk JE; Kuwana T J Biol Chem; 2011 Jan; 286(1):491-501. PubMed ID: 21041309 [TBL] [Abstract][Full Text] [Related]
9. Characterization of the anti-apoptotic mechanism of Bcl-B. Zhai D; Ke N; Zhang H; Ladror U; Joseph M; Eichinger A; Godzik A; Ng SC; Reed JC Biochem J; 2003 Nov; 376(Pt 1):229-36. PubMed ID: 12921534 [TBL] [Abstract][Full Text] [Related]
10. c-Myc functionally cooperates with Bax to induce apoptosis. Juin P; Hunt A; Littlewood T; Griffiths B; Swigart LB; Korsmeyer S; Evan G Mol Cell Biol; 2002 Sep; 22(17):6158-69. PubMed ID: 12167710 [TBL] [Abstract][Full Text] [Related]
11. Structural biology of the Bcl-2 family of proteins. Petros AM; Olejniczak ET; Fesik SW Biochim Biophys Acta; 2004 Mar; 1644(2-3):83-94. PubMed ID: 14996493 [TBL] [Abstract][Full Text] [Related]
12. Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X(L). Lama D; Sankararamakrishnan R J Comput Aided Mol Des; 2011 May; 25(5):413-26. PubMed ID: 21523491 [TBL] [Abstract][Full Text] [Related]
13. Sequence and helicity requirements for the proapoptotic activity of Bax BH3 peptides. Shangary S; Oliver CL; Tillman TS; Cascio M; Johnson DE Mol Cancer Ther; 2004 Nov; 3(11):1343-54. PubMed ID: 15542773 [TBL] [Abstract][Full Text] [Related]
14. Anti-apoptotic Bcl-XL protein in complex with BH3 peptides of pro-apoptotic Bak, Bad, and Bim proteins: comparative molecular dynamics simulations. Lama D; Sankararamakrishnan R Proteins; 2008 Nov; 73(2):492-514. PubMed ID: 18452209 [TBL] [Abstract][Full Text] [Related]
15. Functional identification of the apoptosis effector BH3 domain in cellular protein BNIP1. Yasuda M; Chinnadurai G Oncogene; 2000 May; 19(19):2363-7. PubMed ID: 10822388 [TBL] [Abstract][Full Text] [Related]
16. In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins. Senft D; Weber A; Saathoff F; Berking C; Heppt MV; Kammerbauer C; Rothenfusser S; Kellner S; Kurgyis Z; Besch R; Häcker G Cell Death Dis; 2015 Nov; 6(11):e1996. PubMed ID: 26610208 [TBL] [Abstract][Full Text] [Related]
17. An interconnected hierarchical model of cell death regulation by the BCL-2 family. Chen HC; Kanai M; Inoue-Yamauchi A; Tu HC; Huang Y; Ren D; Kim H; Takeda S; Reyna DE; Chan PM; Ganesan YT; Liao CP; Gavathiotis E; Hsieh JJ; Cheng EH Nat Cell Biol; 2015 Oct; 17(10):1270-81. PubMed ID: 26344567 [TBL] [Abstract][Full Text] [Related]
18. Regulation of apoptosis by BH3 domains in a cell-free system. Cosulich SC; Worrall V; Hedge PJ; Green S; Clarke PR Curr Biol; 1997 Dec; 7(12):913-20. PubMed ID: 9382837 [TBL] [Abstract][Full Text] [Related]
19. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis. Huang K; O'Neill KL; Li J; Zhou W; Han N; Pang X; Wu W; Struble L; Borgstahl G; Liu Z; Zhang L; Luo X Cell Res; 2019 Nov; 29(11):942-952. PubMed ID: 31551537 [TBL] [Abstract][Full Text] [Related]
20. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53. Zhang J; Huang K; O'Neill KL; Pang X; Luo X Cell Death Dis; 2016 Jun; 7(6):e2266. PubMed ID: 27310874 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]