BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 12642697)

  • 21. A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus.
    Mayo LD; Donner DB
    Proc Natl Acad Sci U S A; 2001 Sep; 98(20):11598-603. PubMed ID: 11504915
    [TBL] [Abstract][Full Text] [Related]  

  • 22. C-terminal ubiquitination of p53 contributes to nuclear export.
    Lohrum MA; Woods DB; Ludwig RL; Bálint E; Vousden KH
    Mol Cell Biol; 2001 Dec; 21(24):8521-32. PubMed ID: 11713287
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination.
    O'Keefe K; Li H; Zhang Y
    Mol Cell Biol; 2003 Sep; 23(18):6396-405. PubMed ID: 12944468
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6.
    Freedman DA; Levine AJ
    Mol Cell Biol; 1998 Dec; 18(12):7288-93. PubMed ID: 9819415
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Regulation of p53 nuclear export through sequential changes in conformation and ubiquitination.
    Nie L; Sasaki M; Maki CG
    J Biol Chem; 2007 May; 282(19):14616-25. PubMed ID: 17371868
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination.
    Nakamura S; Roth JA; Mukhopadhyay T
    Mol Cell Biol; 2000 Dec; 20(24):9391-8. PubMed ID: 11094089
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation.
    Louria-Hayon I; Grossman T; Sionov RV; Alsheich O; Pandolfi PP; Haupt Y
    J Biol Chem; 2003 Aug; 278(35):33134-41. PubMed ID: 12810724
    [TBL] [Abstract][Full Text] [Related]  

  • 28. MDM2-dependent ubiquitination of nuclear and cytoplasmic P53.
    Yu ZK; Geyer RK; Maki CG
    Oncogene; 2000 Nov; 19(51):5892-7. PubMed ID: 11127820
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Monoubiquitination: the signal for p53 nuclear export?
    Brooks CL; Li M; Gu W
    Cell Cycle; 2004 Apr; 3(4):436-8. PubMed ID: 14976431
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Overexpression of Mdm2 and MdmX fusion proteins alters p53 mediated transactivation, ubiquitination, and degradation.
    Ghosh M; Huang K; Berberich SJ
    Biochemistry; 2003 Mar; 42(8):2291-9. PubMed ID: 12600196
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mdm2 inhibition of p53 induces E2F1 transactivation via p21.
    Wunderlich M; Berberich SJ
    Oncogene; 2002 Jun; 21(28):4414-21. PubMed ID: 12080472
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Control of p53 ubiquitination and nuclear export by MDM2 and ARF.
    Zhang Y; Xiong Y
    Cell Growth Differ; 2001 Apr; 12(4):175-86. PubMed ID: 11331246
    [TBL] [Abstract][Full Text] [Related]  

  • 33. An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.
    Boyd SD; Tsai KY; Jacks T
    Nat Cell Biol; 2000 Sep; 2(9):563-8. PubMed ID: 10980695
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Controlled access of p53 to the nucleus regulates its proteasomal degradation by MDM2.
    Davis JR; Mossalam M; Lim CS
    Mol Pharm; 2013 Apr; 10(4):1340-9. PubMed ID: 23398638
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5.
    Dai MS; Lu H
    J Biol Chem; 2004 Oct; 279(43):44475-82. PubMed ID: 15308643
    [TBL] [Abstract][Full Text] [Related]  

  • 36. MEK-ERK signaling controls Hdm2 oncoprotein expression by regulating hdm2 mRNA export to the cytoplasm.
    Phelps M; Phillips A; Darley M; Blaydes JP
    J Biol Chem; 2005 Apr; 280(17):16651-8. PubMed ID: 15723837
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation.
    Stommel JM; Wahl GM
    EMBO J; 2004 Apr; 23(7):1547-56. PubMed ID: 15029243
    [TBL] [Abstract][Full Text] [Related]  

  • 38. MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation.
    Wang C; Ivanov A; Chen L; Fredericks WJ; Seto E; Rauscher FJ; Chen J
    EMBO J; 2005 Sep; 24(18):3279-90. PubMed ID: 16107876
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.
    Llanos S; Clark PA; Rowe J; Peters G
    Nat Cell Biol; 2001 May; 3(5):445-52. PubMed ID: 11331871
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Nuclear and cytoplasmic degradation of endogenous p53 and HDM2 occurs during down-regulation of the p53 response after multiple types of DNA damage.
    Joseph TW; Zaika A; Moll UM
    FASEB J; 2003 Sep; 17(12):1622-30. PubMed ID: 12958168
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.