BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 12644586)

  • 1. Anthracyclines induce accumulation of iron in ferritin in myocardial and neoplastic cells: inhibition of the ferritin iron mobilization pathway.
    Kwok JC; Richardson DR
    Mol Pharmacol; 2003 Apr; 63(4):849-61. PubMed ID: 12644586
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Examination of the mechanism(s) involved in doxorubicin-mediated iron accumulation in ferritin: studies using metabolic inhibitors, protein synthesis inhibitors, and lysosomotropic agents.
    Kwok JC; Richardson DR
    Mol Pharmacol; 2004 Jan; 65(1):181-95. PubMed ID: 14722250
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Secondary alcohol metabolites mediate iron delocalization in cytosolic fractions of myocardial biopsies exposed to anticancer anthracyclines. Novel linkage between anthracycline metabolism and iron-induced cardiotoxicity.
    Minotti G; Cavaliere AF; Mordente A; Rossi M; Schiavello R; Zamparelli R; Possati G
    J Clin Invest; 1995 Apr; 95(4):1595-605. PubMed ID: 7706466
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unexpected anthracycline-mediated alterations in iron-regulatory protein-RNA-binding activity: the iron and copper complexes of anthracyclines decrease RNA-binding activity.
    Kwok JC; Richardson DR
    Mol Pharmacol; 2002 Oct; 62(4):888-900. PubMed ID: 12237336
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Iron chelation by clinically relevant anthracyclines: alteration in expression of iron-regulated genes and atypical changes in intracellular iron distribution and trafficking.
    Xu X; Sutak R; Richardson DR
    Mol Pharmacol; 2008 Mar; 73(3):833-44. PubMed ID: 18029550
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Doxorubicin paradoxically protects cardiomyocytes against iron-mediated toxicity: role of reactive oxygen species and ferritin.
    Corna G; Santambrogio P; Minotti G; Cairo G
    J Biol Chem; 2004 Apr; 279(14):13738-45. PubMed ID: 14739295
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The mechanism of nitrogen monoxide (NO)-mediated iron mobilization from cells. NO intercepts iron before incorporation into ferritin and indirectly mobilizes iron from ferritin in a glutathione-dependent manner.
    Watts RN; Richardson DR
    Eur J Biochem; 2002 Jul; 269(14):3383-92. PubMed ID: 12135476
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Doxorubicin-dependent reduction of ferrylmyoglobin and inhibition of lipid peroxidation: implications for cardiotoxicity of anticancer anthracyclines.
    Menna P; Salvatorelli E; Giampietro R; Liberi G; Teodori G; Calafiore AM; Minotti G
    Chem Res Toxicol; 2002 Sep; 15(9):1179-89. PubMed ID: 12230412
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular pharmacology of the interaction of anthracyclines with iron.
    Xu X; Persson HL; Richardson DR
    Mol Pharmacol; 2005 Aug; 68(2):261-71. PubMed ID: 15883202
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Doxorubicin irreversibly inactivates iron regulatory proteins 1 and 2 in cardiomyocytes: evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy.
    Minotti G; Ronchi R; Salvatorelli E; Menna P; Cairo G
    Cancer Res; 2001 Dec; 61(23):8422-8. PubMed ID: 11731422
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism.
    Lane DJ; Chikhani S; Richardson V; Richardson DR
    Biochim Biophys Acta; 2013 Jun; 1833(6):1527-41. PubMed ID: 23481043
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Release of iron from ferritin by cardiotoxic anthracycline antibiotics.
    Thomas CE; Aust SD
    Arch Biochem Biophys; 1986 Aug; 248(2):684-9. PubMed ID: 3017216
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ferritin stimulation of hydroxyl radical production by rat liver nuclei.
    Kukiełka E; Cederbaum AI
    Arch Biochem Biophys; 1994 Jan; 308(1):70-7. PubMed ID: 8311476
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IRP1-independent alterations of cardiac iron metabolism in doxorubicin-treated mice.
    Corna G; Galy B; Hentze MW; Cairo G
    J Mol Med (Berl); 2006 Jul; 84(7):551-60. PubMed ID: 16770644
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Iron transfer form transferrin to ferritin mediated by polyphosphate compounds.
    Konopka K; Mareschal JC; Crichton RR
    Biochim Biophys Acta; 1981 Nov; 677(3-4):417-23. PubMed ID: 6271255
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Detection and quantitation of iron in ferritin, transferrin and labile iron pool (LIP) in cardiomyocytes using
    Krijt M; Jirkovska A; Kabickova T; Melenovsky V; Petrak J; Vyoral D
    Biochim Biophys Acta Gen Subj; 2018 Dec; 1862(12):2895-2901. PubMed ID: 30279145
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased concentrations of iron and isoferritins in the lower respiratory tract of patients with stable cystic fibrosis.
    Stites SW; Plautz MW; Bailey K; O'Brien-Ladner AR; Wesselius LJ
    Am J Respir Crit Care Med; 1999 Sep; 160(3):796-801. PubMed ID: 10471599
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ferritin as a cytosol iron transport intermediate in human reticulocytes.
    Speyer BE; Fielding J
    Br J Haematol; 1979 Jun; 42(2):255-67. PubMed ID: 465371
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ferritin heavy chain as main mediator of preventive effect of metformin against mitochondrial damage induced by doxorubicin in cardiomyocytes.
    Asensio-Lopez MC; Sanchez-Mas J; Pascual-Figal DA; de Torre C; Valdes M; Lax A
    Free Radic Biol Med; 2014 Feb; 67():19-29. PubMed ID: 24231192
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of a prolonged superoxide flux on transferrin and ferritin.
    Paul T
    Arch Biochem Biophys; 2000 Oct; 382(2):253-61. PubMed ID: 11068877
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.