BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 12645571)

  • 1. Catalytic properties of mutant 23 S ribosomes resistant to oxazolidinones.
    Bobkova EV; Yan YP; Jordan DB; Kurilla MG; Pompliano DL
    J Biol Chem; 2003 Mar; 278(11):9802-7. PubMed ID: 12645571
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action.
    Xiong L; Kloss P; Douthwaite S; Andersen NM; Swaney S; Shinabarger DL; Mankin AS
    J Bacteriol; 2000 Oct; 182(19):5325-31. PubMed ID: 10986233
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oxazolidinones mechanism of action: inhibition of the first peptide bond formation.
    Patel U; Yan YP; Hobbs FW; Kaczmarczyk J; Slee AM; Pompliano DL; Kurilla MG; Bobkova EV
    J Biol Chem; 2001 Oct; 276(40):37199-205. PubMed ID: 11483595
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit.
    Thompson J; Kim DF; O'Connor M; Lieberman KR; Bayfield MA; Gregory ST; Green R; Noller HF; Dahlberg AE
    Proc Natl Acad Sci U S A; 2001 Jul; 98(16):9002-7. PubMed ID: 11470897
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Studies on the catalytic rate constant of ribosomal peptidyltransferase.
    Synetos D; Coutsogeorgopoulos C
    Biochim Biophys Acta; 1987 Feb; 923(2):275-85. PubMed ID: 3545299
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Resistance mutations in 23 S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center.
    Kloss P; Xiong L; Shinabarger DL; Mankin AS
    J Mol Biol; 1999 Nov; 294(1):93-101. PubMed ID: 10556031
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Yeast ribosomal protein deletion mutants possess altered peptidyltransferase activity and different sensitivity to cycloheximide.
    Dresios J; Panopoulos P; Frantziou CP; Synetos D
    Biochemistry; 2001 Jul; 40(27):8101-8. PubMed ID: 11434779
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A sparsomycin-resistant mutant of Halobacterium salinarium lacks a modification at nucleotide U2603 in the peptidyl transferase centre of 23 S rRNA.
    Lázaro E; Rodriguez-Fonseca C; Porse B; Ureña D; Garrett RA; Ballesta JP
    J Mol Biol; 1996 Aug; 261(2):231-8. PubMed ID: 8757290
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oxazolidinone antibiotics target the P site on Escherichia coli ribosomes.
    Aoki H; Ke L; Poppe SM; Poel TJ; Weaver EA; Gadwood RC; Thomas RC; Shinabarger DL; Ganoza MC
    Antimicrob Agents Chemother; 2002 Apr; 46(4):1080-5. PubMed ID: 11897593
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of polyamines on the inhibition of peptidyltransferase by antibiotics: revisiting the mechanism of chloramphenicol action.
    Xaplanteri MA; Andreou A; Dinos GP; Kalpaxis DL
    Nucleic Acids Res; 2003 Sep; 31(17):5074-83. PubMed ID: 12930958
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutations in the peptidyl transferase center of 23 S rRNA reveal the site of action of sparsomycin, a universal inhibitor of translation.
    Tan GT; DeBlasio A; Mankin AS
    J Mol Biol; 1996 Aug; 261(2):222-30. PubMed ID: 8757289
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The site of action of oxazolidinone antibiotics in living bacteria and in human mitochondria.
    Leach KL; Swaney SM; Colca JR; McDonald WG; Blinn JR; Thomasco LM; Gadwood RC; Shinabarger D; Xiong L; Mankin AS
    Mol Cell; 2007 May; 26(3):393-402. PubMed ID: 17499045
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protected nucleotide G2608 in 23S rRNA confers resistance to oxazolidinones in E. coli.
    Xu J; Golshani A; Aoki H; Remme J; Chosay J; Shinabarger DL; Ganoza MC
    Biochem Biophys Res Commun; 2005 Mar; 328(2):471-6. PubMed ID: 15694371
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kinetics of inhibition of rabbit reticulocyte peptidyltransferase by anisomycin and sparsomycin.
    Ioannou M; Coutsogeorgopoulos C; Synetos D
    Mol Pharmacol; 1998 Jun; 53(6):1089-96. PubMed ID: 9614213
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutational analysis of the donor substrate binding site of the ribosomal peptidyltransferase center.
    Saarma U; Spahn CM; Nierhaus KH; Remme J
    RNA; 1998 Feb; 4(2):189-94. PubMed ID: 9570318
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of ribosomal peptidyltransferase by chloramphenicol. Kinetic studies.
    Drainas D; Kalpaxis DL; Coutsogeorgopoulos C
    Eur J Biochem; 1987 Apr; 164(1):53-8. PubMed ID: 3549307
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Peptidyl transferase antibiotics perturb the relative positioning of the 3'-terminal adenosine of P/P'-site-bound tRNA and 23S rRNA in the ribosome.
    Kirillov SV; Porse BT; Garrett RA
    RNA; 1999 Aug; 5(8):1003-13. PubMed ID: 10445875
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural basis of translation inhibition by cadazolid, a novel quinoxolidinone antibiotic.
    Scaiola A; Leibundgut M; Boehringer D; Caspers P; Bur D; Locher HH; Rueedi G; Ritz D
    Sci Rep; 2019 Apr; 9(1):5634. PubMed ID: 30948752
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of sparsomycin analogues on the puromycin-peptidyl transferase reaction on ribosomes.
    Lee CK; Vince R
    J Med Chem; 1978 Feb; 21(2):176-9. PubMed ID: 340693
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ribosomal protein L5 helps anchor peptidyl-tRNA to the P-site in Saccharomyces cerevisiae.
    Meskauskas A; Dinman JD
    RNA; 2001 Aug; 7(8):1084-96. PubMed ID: 11497428
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.