BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

438 related articles for article (PubMed ID: 12646418)

  • 1. HNF-1alpha and endodermal transcription factors cooperatively activate Fabpl: MODY3 mutations abrogate cooperativity.
    Divine JK; McCaul SP; Simon TC
    Am J Physiol Gastrointest Liver Physiol; 2003 Jul; 285(1):G62-72. PubMed ID: 12646418
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GATA-4, GATA-5, and GATA-6 activate the rat liver fatty acid binding protein gene in concert with HNF-1alpha.
    Divine JK; Staloch LJ; Haveri H; Jacobsen CM; Wilson DB; Heikinheimo M; Simon TC
    Am J Physiol Gastrointest Liver Physiol; 2004 Nov; 287(5):G1086-99. PubMed ID: 14715527
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanisms of mutual functional interactions between HNF-4alpha and HNF-1alpha revealed by mutations that cause maturity onset diabetes of the young.
    Rowley CW; Staloch LJ; Divine JK; McCaul SP; Simon TC
    Am J Physiol Gastrointest Liver Physiol; 2006 Mar; 290(3):G466-75. PubMed ID: 16223942
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 435-bp liver regulatory sequence in the liver fatty acid binding protein (L-FABP) gene is sufficient to modulate liver regional expression in transgenic zebrafish.
    Her GM; Yeh YH; Wu JL
    Dev Dyn; 2003 Jul; 227(3):347-56. PubMed ID: 12815620
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of mutations in HNF-1alpha and HNF-1beta on the transcriptional regulation of human sucrase-isomaltase in Caco-2 cells.
    Gu N; Suzuki N; Takeda J; Adachi T; Tsujimoto G; Aoki N; Ishihara A; Tsuda K; Yasuda K
    Biochem Biophys Res Commun; 2004 Dec; 325(1):308-13. PubMed ID: 15522234
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human insulin gene is a target gene of hepatocyte nuclear factor-1alpha (HNF-1alpha) and HNF-1beta.
    Okita K; Yang Q; Yamagata K; Hangenfeldt KA; Miyagawa J; Kajimoto Y; Nakajima H; Namba M; Wollheim CB; Hanafusa T; Matsuzawa Y
    Biochem Biophys Res Commun; 1999 Sep; 263(2):566-9. PubMed ID: 10491332
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha.
    Krasinski SD; Van Wering HM; Tannemaat MR; Grand RJ
    Am J Physiol Gastrointest Liver Physiol; 2001 Jul; 281(1):G69-84. PubMed ID: 11408257
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels.
    Richter S; Shih DQ; Pearson ER; Wolfrum C; Fajans SS; Hattersley AT; Stoffel M
    Diabetes; 2003 Dec; 52(12):2989-95. PubMed ID: 14633861
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter.
    van Wering HM; Huibregtse IL; van der Zwan SM; de Bie MS; Dowling LN; Boudreau F; Rings EH; Grand RJ; Krasinski SD
    J Biol Chem; 2002 Aug; 277(31):27659-67. PubMed ID: 12011060
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MODY associated with two novel hepatocyte nuclear factor-1alpha loss-of-function mutations (P112L and Q466X).
    Bjørkhaug L; Ye H; Horikawa Y; Søvik O; Molven A; Njølstad PR
    Biochem Biophys Res Commun; 2000 Dec; 279(3):792-8. PubMed ID: 11162430
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Decreased glibenclamide uptake in hepatocytes of hepatocyte nuclear factor-1alpha-deficient mice: a mechanism for hypersensitivity to sulfonylurea therapy in patients with maturity-onset diabetes of the young, type 3 (MODY3).
    Boileau P; Wolfrum C; Shih DQ; Yang TA; Wolkoff AW; Stoffel M
    Diabetes; 2002 Dec; 51 Suppl 3():S343-8. PubMed ID: 12475773
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Growth hormone regulates the expression of hepatocyte nuclear factor-3 gamma and other liver-enriched transcription factors in the bovine liver.
    Eleswarapu S; Jiang H
    J Endocrinol; 2005 Jan; 184(1):95-105. PubMed ID: 15642787
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutation P291fsinsC in the transcription factor hepatocyte nuclear factor-1alpha is dominant negative.
    Yamagata K; Yang Q; Yamamoto K; Iwahashi H; Miyagawa J; Okita K; Yoshiuchi I; Miyazaki J; Noguchi T; Nakajima H; Namba M; Hanafusa T; Matsuzawa Y
    Diabetes; 1998 Aug; 47(8):1231-5. PubMed ID: 9703322
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Liver-enriched transcription factors, HNF-1, HNF-3, and C/EBP, are major contributors to the strong activity of the chicken CYP2H1 promoter in chick embryo hepatocytes.
    Dogra SC; May BK
    DNA Cell Biol; 1997 Dec; 16(12):1407-18. PubMed ID: 9428789
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function.
    Hansen SK; Párrizas M; Jensen ML; Pruhova S; Ek J; Boj SF; Johansen A; Maestro MA; Rivera F; Eiberg H; Andel M; Lebl J; Pedersen O; Ferrer J; Hansen T
    J Clin Invest; 2002 Sep; 110(6):827-33. PubMed ID: 12235114
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure/function studies of hepatocyte nuclear factor-1alpha, a diabetes-associated transcription factor.
    Yang Q; Yamagata K; Yamamoto K; Miyagawa J; Takeda J; Iwasaki N; Iwahashi H; Yoshiuchi I; Namba M; Miyazaki J; Hanafusa T; Matsuzawa Y
    Biochem Biophys Res Commun; 1999 Dec; 266(1):196-202. PubMed ID: 10581189
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification and functional characterization of a novel mutation of hepatocyte nuclear factor-1alpha gene in a Korean family with MODY3.
    Kim KA; Kang K; Chi YI; Chang I; Lee MK; Kim KW; Shoelson SE; Lee MS
    Diabetologia; 2003 May; 46(5):721-7. PubMed ID: 12712243
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional study of the E276Q mutant hepatocyte nuclear factor-4alpha found in type 1 maturity-onset diabetes of the young: impaired synergy with chicken ovalbumin upstream promoter transcription factor II on the hepatocyte nuclear factor-1 promoter.
    Suaud L; Hemimou Y; Formstecher P; Laine B
    Diabetes; 1999 May; 48(5):1162-7. PubMed ID: 10331424
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutations in the hepatocyte nuclear factor-1alpha gene in MODY and early-onset NIDDM: evidence for a mutational hotspot in exon 4.
    Kaisaki PJ; Menzel S; Lindner T; Oda N; Rjasanowski I; Sahm J; Meincke G; Schulze J; Schmechel H; Petzold C; Ledermann HM; Sachse G; Boriraj VV; Menzel R; Kerner W; Turner RC; Yamagata K; Bell GI
    Diabetes; 1997 Mar; 46(3):528-35. PubMed ID: 9032114
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hepatocyte nuclear factor 1 and the glucocorticoid receptor synergistically activate transcription of the rat insulin-like growth factor binding protein-1 gene.
    Suh DS; Rechler MM
    Mol Endocrinol; 1997 Nov; 11(12):1822-31. PubMed ID: 9369450
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.