163 related articles for article (PubMed ID: 12647310)
1. Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d]pyrimidine nucleoside analogues.
De Clercq E
Med Res Rev; 2003 May; 23(3):253-74. PubMed ID: 12647310
[TBL] [Abstract][Full Text] [Related]
2. Bicyclic pyrimidine nucleoside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication.
Balzarini J; McGuigan C
J Antimicrob Chemother; 2002 Jul; 50(1):5-9. PubMed ID: 12096000
[TBL] [Abstract][Full Text] [Related]
3. Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides.
Balzarini J; McGuigan C
Biochim Biophys Acta; 2002 Jul; 1587(2-3):287-95. PubMed ID: 12084470
[TBL] [Abstract][Full Text] [Related]
4. 2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743.
McGuigan C; Derudas M; Quintiliani M; Andrei G; Snoeck R; Henson G; Balzarini J
Bioorg Med Chem Lett; 2009 Nov; 19(22):6264-7. PubMed ID: 19833513
[TBL] [Abstract][Full Text] [Related]
5. Bicyclic nucleoside inhibitors of varicella-zoster virus modified on the sugar moiety: 3' and 5' derivatives.
Luoni GM; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Antivir Chem Chemother; 2004 Nov; 15(6):333-41. PubMed ID: 15646647
[TBL] [Abstract][Full Text] [Related]
6. Bicyclic nucleoside inhibitors of varicella-zoster virus: 5'-chloro and 3'-chloro derivatives.
Luoni G; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):931-3. PubMed ID: 14565314
[TBL] [Abstract][Full Text] [Related]
7. Metabolic and pharmacological characteristics of the bicyclic nucleoside analogues (BCNAs) as highly selective inhibitors of varicella-zoster virus (VZV).
Sienaert R; Naesens L; Brancale A; Carangio A; Andrei G; Snoeck R; Van Kuilenburg A; De Clercq E; McGuigan C; Balzarini J
Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):995-7. PubMed ID: 14565329
[No Abstract] [Full Text] [Related]
8. Bicyclic anti-VZV nucleosides: thieno analogues bearing an alkylphenyl side chain have reduced antiviral activity.
Angell A; McGuigan C; Garcia Sevillano L; Snoeck R; Andrei G; De Clercq E; Balzarini J
Bioorg Med Chem Lett; 2004 May; 14(10):2397-9. PubMed ID: 15109620
[TBL] [Abstract][Full Text] [Related]
9. Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase.
Sienaert R; Andrei G; Snoeck R; De Clercq E; McGuigan C; Balzarini J
Biochem Biophys Res Commun; 2004 Mar; 315(4):877-83. PubMed ID: 14985094
[TBL] [Abstract][Full Text] [Related]
10. Bicyclic furo pyrimidine nucleosides with aryloxyphenyl and halophenyl substituted side chains as potent and selective varicella-zoster virus inhibitors.
Blewett S; McGuigan C; Barucki H; Andrei G; Snoeck R; De Clercq E; Balzarini J
Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):1063-6. PubMed ID: 11562959
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and antiviral evaluation of 6-(alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one nucleosides and analogues with ethynyl, ethenyl, and ethyl spacers at C6 of the furopyrimidine core.
Robins MJ; Nowak I; Rajwanshi VK; Miranda K; Cannon JF; Peterson MA; Andrei G; Snoeck R; De Clercq E; Balzarini J
J Med Chem; 2007 Aug; 50(16):3897-905. PubMed ID: 17622128
[TBL] [Abstract][Full Text] [Related]
12. Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus.
McGuigan C; Pathirana RN; Migliore M; Adak R; Luoni G; Jones AT; Díez-Torrubia A; Camarasa MJ; Velázquez S; Henson G; Verbeken E; Sienaert R; Naesens L; Snoeck R; Andrei G; Balzarini J
J Antimicrob Chemother; 2007 Dec; 60(6):1316-30. PubMed ID: 17956908
[TBL] [Abstract][Full Text] [Related]
13. Specific recognition of the bicyclic pyrimidine nucleoside analogs, a new class of highly potent and selective inhibitors of varicella-zoster virus (VZV), by the VZV-encoded thymidine kinase.
Sienaert R; Naesens L; Brancale A; De Clercq E; McGuigan C; Balzarini J
Mol Pharmacol; 2002 Feb; 61(2):249-54. PubMed ID: 11809847
[TBL] [Abstract][Full Text] [Related]
14. Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase.
Balzarini J; Sienaert R; Liekens S; Van Kuilenburg A; Carangio A; Esnouf R; De Clercq E; McGuigan C
Mol Pharmacol; 2002 May; 61(5):1140-5. PubMed ID: 11961132
[TBL] [Abstract][Full Text] [Related]
15. Synthesis of unusual bicyclic nucleosides bearing an unsaturated side-chain, as potential inhibitors of varicella-zoster virus (VZV).
Bidet O; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):817-9. PubMed ID: 14565286
[No Abstract] [Full Text] [Related]
16. Synthesis and biological evaluation of 6-(alkyn-1-yl)furo[2,3-d]pyrimidin-2(3H)-one base and nucleoside derivatives.
Robins MJ; Miranda K; Rajwanshi VK; Peterson MA; Andrei G; Snoeck R; De Clercq E; Balzarini J
J Med Chem; 2006 Jan; 49(1):391-8. PubMed ID: 16392824
[TBL] [Abstract][Full Text] [Related]
17. Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chain.
McGuigan C; Barucki H; Carangio A; Blewett S; Andrei G; Snoeck R; De Clercq E; Balzarini J; Erichsen JT
J Med Chem; 2000 Dec; 43(26):4993-7. PubMed ID: 11150169
[TBL] [Abstract][Full Text] [Related]
18. Bicyclic nucleoside inhibitors of varicella-zoster virus: effect of terminal aryl substitution in the side-chain.
Carangio A; Srinivasan S; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Antivir Chem Chemother; 2002 Sep; 13(5):263-71. PubMed ID: 12630674
[TBL] [Abstract][Full Text] [Related]
19. Evaluation of novel phosphoramidate ProTides of the 2'-fluoro derivatives of a potent anti-varicella zoster virus bicyclic nucleoside analogue.
Derudas M; Quintiliani M; Brancale A; Andrei G; Snoeck R; Balzarini J; McGuigan C
Antivir Chem Chemother; 2010 Oct; 21(1):15-31. PubMed ID: 21045257
[TBL] [Abstract][Full Text] [Related]
20. Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides.
Andrei G; Sienaert R; McGuigan C; De Clercq E; Balzarini J; Snoeck R
Antimicrob Agents Chemother; 2005 Mar; 49(3):1081-6. PubMed ID: 15728906
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
