BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 12648071)

  • 1. Resistance to spontaneous apoptosis in acute myeloid leukaemia blasts is associated with p-glycoprotein expression and function, but not with the presence of FLT3 internal tandem duplications.
    Pallis M; Turzanski J; Grundy M; Seedhouse C; Russell N
    Br J Haematol; 2003 Mar; 120(6):1009-16. PubMed ID: 12648071
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The expression of P-glycoprotein in AML cells with FLT3 internal tandem duplications is associated with reduced apoptosis in response to FLT3 inhibitors.
    Hunter HM; Pallis M; Seedhouse CH; Grundy M; Gray C; Russell NH
    Br J Haematol; 2004 Oct; 127(1):26-33. PubMed ID: 15384974
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance.
    Zwaan CM; Meshinchi S; Radich JP; Veerman AJ; Huismans DR; Munske L; Podleschny M; Hählen K; Pieters R; Zimmermann M; Reinhardt D; Harbott J; Creutzig U; Kaspers GJ; Griesinger F
    Blood; 2003 Oct; 102(7):2387-94. PubMed ID: 12816873
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of the transforming activity of FLT3 internal tandem duplication mutants from AML patients by a tyrosine kinase inhibitor.
    Tse KF; Allebach J; Levis M; Smith BD; Bohmer FD; Small D
    Leukemia; 2002 Oct; 16(10):2027-36. PubMed ID: 12357354
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of c-Kit and functional drug efflux are correlated in de novo acute myeloid leukaemia.
    Sincock PM; Ashman LK
    Leukemia; 1997 Nov; 11(11):1850-7. PubMed ID: 9369417
    [TBL] [Abstract][Full Text] [Related]  

  • 6. P-glycoprotein plays a drug-efflux-independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphingomyelin-ceramide apoptotic pathway.
    Pallis M; Russell N
    Blood; 2000 May; 95(9):2897-904. PubMed ID: 10779437
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prognostic significance of FLT3 internal tandem repeat in patients with de novo acute myeloid leukemia treated with reinforced courses of chemotherapy.
    Boissel N; Cayuela JM; Preudhomme C; Thomas X; Grardel N; Fund X; Tigaud I; Raffoux E; Rousselot P; Sigaux F; Degos L; Castaigne S; Fenaux P; Dombret H
    Leukemia; 2002 Sep; 16(9):1699-704. PubMed ID: 12200684
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Clinical impact of internal tandem duplications and activating point mutations in FLT3 in acute myeloid leukemia in elderly patients.
    Andersson A; Johansson B; Lassen C; Mitelman F; Billström R; Fioretos T
    Eur J Haematol; 2004 May; 72(5):307-13. PubMed ID: 15059064
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations.
    Mizuki M; Schwable J; Steur C; Choudhary C; Agrawal S; Sargin B; Steffen B; Matsumura I; Kanakura Y; Böhmer FD; Müller-Tidow C; Berdel WE; Serve H
    Blood; 2003 Apr; 101(8):3164-73. PubMed ID: 12468433
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Internal tandem duplications of Flt3 gene (Flt3/ITD) predicts a poor post-remission outcome in adult patients with acute non-promyelocytic leukemia.
    Ciolli S; Vannucchi AM; Leoni F; Nozzoli C; Longo G; Salati A; Pancrazzi A; Bianchi L; Gigli F; Bosi A
    Leuk Lymphoma; 2004 Jan; 45(1):73-8. PubMed ID: 15061200
    [TBL] [Abstract][Full Text] [Related]  

  • 11. P-glycoprotein in acute myeloid leukaemia: therapeutic implications of its association with both a multidrug-resistant and an apoptosis-resistant phenotype.
    Pallis M; Turzanski J; Higashi Y; Russell N
    Leuk Lymphoma; 2002 Jun; 43(6):1221-8. PubMed ID: 12152989
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm.
    Fröhling S; Schlenk RF; Breitruck J; Benner A; Kreitmeier S; Tobis K; Döhner H; Döhner K;
    Blood; 2002 Dec; 100(13):4372-80. PubMed ID: 12393388
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quantitative, real-time polymerase chain reactions for FLT3 internal tandem duplications are highly sensitive and specific.
    Stirewalt DL; Willman CL; Radich JP
    Leuk Res; 2001 Dec; 25(12):1085-8. PubMed ID: 11684280
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Risk assessment in patients with acute myeloid leukemia and a normal karyotype.
    Bienz M; Ludwig M; Leibundgut EO; Mueller BU; Ratschiller D; Solenthaler M; Fey MF; Pabst T
    Clin Cancer Res; 2005 Feb; 11(4):1416-24. PubMed ID: 15746041
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin.
    Linenberger ML; Hong T; Flowers D; Sievers EL; Gooley TA; Bennett JM; Berger MS; Leopold LH; Appelbaum FR; Bernstein ID
    Blood; 2001 Aug; 98(4):988-94. PubMed ID: 11493443
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biological characteristics and prognosis of adult acute myeloid leukemia with internal tandem duplications in the Flt3 gene.
    Rombouts WJ; Blokland I; Löwenberg B; Ploemacher RE
    Leukemia; 2000 Apr; 14(4):675-83. PubMed ID: 10764154
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FLT3 and its role in the pathogenesis of acute myeloid leukaemia.
    Reilly JT
    Leuk Lymphoma; 2003 Jan; 44(1):1-7. PubMed ID: 12691136
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pgp and FLT3: identification and modulation of two proteins that lead to chemotherapy resistance in acute myeloid leukemia.
    Kappelmayer J; Udvardy M; Antal-Szalmás P
    Curr Med Chem; 2007; 14(5):519-30. PubMed ID: 17346144
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinct poor prognostic subgroups of acute myeloid leukaemia, FLT3-ITD and P-glycoprotein-positive, have contrasting levels of FOXO1.
    Seedhouse CH; Mills KI; Ahluwalia S; Grundy M; Shang S; Burnett AK; Russell NH; Pallis M
    Leuk Res; 2014 Jan; 38(1):131-7. PubMed ID: 24268349
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tandem duplication of the FLT3 gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children.
    Xu F; Taki T; Yang HW; Hanada R; Hongo T; Ohnishi H; Kobayashi M; Bessho F; Yanagisawa M; Hayashi Y
    Br J Haematol; 1999 Apr; 105(1):155-62. PubMed ID: 10233379
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.