114 related articles for article (PubMed ID: 12649292)
21. Conformational properties of the disease-causing Z variant of α1-antitrypsin revealed by theory and experiment.
Kass I; Knaupp AS; Bottomley SP; Buckle AM
Biophys J; 2012 Jun; 102(12):2856-65. PubMed ID: 22735536
[TBL] [Abstract][Full Text] [Related]
22. Genetic variants of alpha1-antitrypsin.
Salahuddin P
Curr Protein Pept Sci; 2010 Mar; 11(2):101-17. PubMed ID: 19751191
[TBL] [Abstract][Full Text] [Related]
23. Alpha 1-antitrypsin polymerisation can occur by both loop A and C sheet mechanisms.
Bottomley SP; Hopkins PC; Whisstock JC
Biochem Biophys Res Commun; 1998 Oct; 251(1):1-5. PubMed ID: 9790897
[TBL] [Abstract][Full Text] [Related]
24. Inhibiting polymerization: new therapeutic strategies for Z alpha1-antitrypsin-related emphysema.
Parfrey H; Dafforn TR; Belorgey D; Lomas DA; Mahadeva R
Am J Respir Cell Mol Biol; 2004 Aug; 31(2):133-9. PubMed ID: 15016619
[TBL] [Abstract][Full Text] [Related]
25. Small molecules block the polymerization of Z alpha1-antitrypsin and increase the clearance of intracellular aggregates.
Mallya M; Phillips RL; Saldanha SA; Gooptu B; Brown SC; Termine DJ; Shirvani AM; Wu Y; Sifers RN; Abagyan R; Lomas DA
J Med Chem; 2007 Nov; 50(22):5357-63. PubMed ID: 17918823
[TBL] [Abstract][Full Text] [Related]
26. Fluorescence correlation spectroscopic study of serpin depolymerization by computationally designed peptides.
Chowdhury P; Wang W; Lavender S; Bunagan MR; Klemke JW; Tang J; Saven JG; Cooperman BS; Gai F
J Mol Biol; 2007 Jun; 369(2):462-73. PubMed ID: 17442346
[TBL] [Abstract][Full Text] [Related]
27. Influence of the P5 residue on alpha1-proteinase inhibitor mechanism.
Chaillan-Huntington CE; Patston PA
J Biol Chem; 1998 Feb; 273(8):4569-73. PubMed ID: 9468513
[TBL] [Abstract][Full Text] [Related]
28. Hypersensitive mousetraps, alpha1-antitrypsin deficiency and dementia.
Lomas DA; Lourbakos A; Cumming SA; Belorgey D
Biochem Soc Trans; 2002 Apr; 30(2):89-92. PubMed ID: 12023831
[TBL] [Abstract][Full Text] [Related]
29. Isolation and characterization of alpha1-proteinase inhibitor from common carp (Cyprinus carpio) seminal plasma.
Wojtczak M; Całka J; Glogowski J; Ciereszko A
Comp Biochem Physiol B Biochem Mol Biol; 2007 Nov; 148(3):264-76. PubMed ID: 17681818
[TBL] [Abstract][Full Text] [Related]
30. Characterization of a human alpha1-antitrypsin variant that is as stable as ovalbumin.
Lee KN; Im H; Kang SW; Yu MH
J Biol Chem; 1998 Jan; 273(5):2509-16. PubMed ID: 9446551
[TBL] [Abstract][Full Text] [Related]
31. The transferable tail: fusion of the N-terminal acidic extension of heparin cofactor II to alpha1-proteinase inhibitor M358R specifically increases the rate of thrombin inhibition.
Sutherland JS; Bhakta V; Filion ML; Sheffield WP
Biochemistry; 2006 Sep; 45(38):11444-52. PubMed ID: 16981704
[TBL] [Abstract][Full Text] [Related]
32. Effect of the Z mutation on the physical and inhibitory properties of alpha 1-antitrypsin.
Lomas DA; Evans DL; Stone SR; Chang WS; Carrell RW
Biochemistry; 1993 Jan; 32(2):500-8. PubMed ID: 8422359
[TBL] [Abstract][Full Text] [Related]
33. Probing the local conformational change of alpha1-antitrypsin.
Baek JH; Im H; Kang UB; Seong KM; Lee C; Kim J; Yu MH
Protein Sci; 2007 Sep; 16(9):1842-50. PubMed ID: 17660256
[TBL] [Abstract][Full Text] [Related]
34. 6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization. Implications for the prevention of Z alpha(1)-antitrypsin-related cirrhosis.
Mahadeva R; Dafforn TR; Carrell RW; Lomas DA
J Biol Chem; 2002 Mar; 277(9):6771-4. PubMed ID: 11773044
[TBL] [Abstract][Full Text] [Related]
35. Identification of a 4-mer peptide inhibitor that effectively blocks the polymerization of pathogenic Z alpha1-antitrypsin.
Chang YP; Mahadeva R; Chang WS; Shukla A; Dafforn TR; Chu YH
Am J Respir Cell Mol Biol; 2006 Nov; 35(5):540-8. PubMed ID: 16778151
[TBL] [Abstract][Full Text] [Related]
36. Probing the unfolding pathway of alpha1-antitrypsin.
James EL; Whisstock JC; Gore MG; Bottomley SP
J Biol Chem; 1999 Apr; 274(14):9482-8. PubMed ID: 10092631
[TBL] [Abstract][Full Text] [Related]
37. Inhibitory conformation of the reactive loop of alpha 1-antitrypsin.
Elliott PR; Lomas DA; Carrell RW; Abrahams JP
Nat Struct Biol; 1996 Aug; 3(8):676-81. PubMed ID: 8756325
[TBL] [Abstract][Full Text] [Related]
38. Comparative cleavage sites within the reactive-site loop of native and oxidized alpha1-proteinase inhibitor by selected bacterial proteinases.
Rapala-Kozik M; Potempa J; Nelson D; Kozik A; Travis J
Biol Chem; 1999 Oct; 380(10):1211-6. PubMed ID: 10595584
[TBL] [Abstract][Full Text] [Related]
39. Full or partial substitution of the reactive center loop of alpha-1-proteinase inhibitor by that of heparin cofactor II: P1 Arg is required for maximal thrombin inhibition.
Filion ML; Bhakta V; Nguyen LH; Liaw PS; Sheffield WP
Biochemistry; 2004 Nov; 43(46):14864-72. PubMed ID: 15544357
[TBL] [Abstract][Full Text] [Related]
40. Conformation of the reactive site loop of alpha 1-proteinase inhibitor probed by limited proteolysis.
Mast AE; Enghild JJ; Salvesen G
Biochemistry; 1992 Mar; 31(10):2720-8. PubMed ID: 1547212
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
