BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 12650604)

  • 1. MKK4 and metastasis suppression: a marriage of signal transduction and metastasis research.
    Robinson VL; Hickson JA; Vander Griend DJ; Dubauskas Z; Rinker-Schaeffer CW
    Clin Exp Metastasis; 2003; 20(1):25-30. PubMed ID: 12650604
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.
    Yamada SD; Hickson JA; Hrobowski Y; Vander Griend DJ; Benson D; Montag A; Karrison T; Huo D; Rutgers J; Adams S; Rinker-Schaeffer CW
    Cancer Res; 2002 Nov; 62(22):6717-23. PubMed ID: 12438272
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mitogen-activated protein kinase kinase 4 metastasis suppressor gene expression is inversely related to histological pattern in advancing human prostatic cancers.
    Kim HL; Vander Griend DJ; Yang X; Benson DA; Dubauskas Z; Yoshida BA; Chekmareva MA; Ichikawa Y; Sokoloff MH; Zhan P; Karrison T; Lin A; Stadler WM; Ichikawa T; Rubin MA; Rinker-Schaeffer CW
    Cancer Res; 2001 Apr; 61(7):2833-7. PubMed ID: 11306453
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitogen-activated protein kinase kinase 4/stress-activated protein/Erk kinase 1 (MKK4/SEK1), a prostate cancer metastasis suppressor gene encoded by human chromosome 17.
    Yoshida BA; Dubauskas Z; Chekmareva MA; Christiano TR; Stadler WM; Rinker-Schaeffer CW
    Cancer Res; 1999 Nov; 59(21):5483-7. PubMed ID: 10554023
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor.
    Teng DH; Perry WL; Hogan JK; Baumgard M; Bell R; Berry S; Davis T; Frank D; Frye C; Hattier T; Hu R; Jammulapati S; Janecki T; Leavitt A; Mitchell JT; Pero R; Sexton D; Schroeder M; Su PH; Swedlund B; Kyriakis JM; Avruch J; Bartel P; Wong AK; Tavtigian SV
    Cancer Res; 1997 Oct; 57(19):4177-82. PubMed ID: 9331070
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disruption of MKK4 signaling reveals its tumor-suppressor role in embryonic stem cells.
    Cazillis M; Bringuier AF; Delautier D; Buisine M; Bernuau D; Gespach C; Groyer A
    Oncogene; 2004 Jun; 23(27):4735-44. PubMed ID: 15122334
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors.
    Wang L; Pan Y; Dai JL
    Oncogene; 2004 Aug; 23(35):5978-85. PubMed ID: 15184866
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New paradigms for the function of JNKK1/MKK4 in controlling growth of disseminated cancer cells.
    Taylor JL; Szmulewitz RZ; Lotan T; Hickson J; Griend DV; Yamada SD; Macleod K; Rinker-Schaeffer CW
    Cancer Lett; 2008 Dec; 272(1):12-22. PubMed ID: 18572308
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitogen-activated protein kinase kinase 4 (MKK4).
    Cuenda A
    Int J Biochem Cell Biol; 2000 Jun; 32(6):581-7. PubMed ID: 10785355
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma.
    Hickson JA; Huo D; Vander Griend DJ; Lin A; Rinker-Schaeffer CW; Yamada SD
    Cancer Res; 2006 Feb; 66(4):2264-70. PubMed ID: 16489030
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene.
    Su GH; Hilgers W; Shekher MC; Tang DJ; Yeo CJ; Hruban RH; Kern SE
    Cancer Res; 1998 Jun; 58(11):2339-42. PubMed ID: 9622070
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of mitogen-activated protein kinase kinase 4 in cancer.
    Whitmarsh AJ; Davis RJ
    Oncogene; 2007 May; 26(22):3172-84. PubMed ID: 17496914
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Up-regulation of MKK4, MKK6 and MKK7 during prostate cancer progression: an important role for SAPK signalling in prostatic neoplasia.
    Lotan TL; Lyon M; Huo D; Taxy JB; Brendler C; Foster BA; Stadler W; Rinker-Schaeffer CW
    J Pathol; 2007 Aug; 212(4):386-94. PubMed ID: 17577251
    [TBL] [Abstract][Full Text] [Related]  

  • 14. c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.
    Lotan T; Hickson J; Souris J; Huo D; Taylor J; Li T; Otto K; Yamada SD; Macleod K; Rinker-Schaeffer CW
    Cancer Res; 2008 Apr; 68(7):2166-75. PubMed ID: 18381422
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines.
    Tournier C; Dong C; Turner TK; Jones SN; Flavell RA; Davis RJ
    Genes Dev; 2001 Jun; 15(11):1419-26. PubMed ID: 11390361
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7.
    Vander Griend DJ; Kocherginsky M; Hickson JA; Stadler WM; Lin A; Rinker-Schaeffer CW
    Cancer Res; 2005 Dec; 65(23):10984-91. PubMed ID: 16322247
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity.
    Yang D; Tournier C; Wysk M; Lu HT; Xu J; Davis RJ; Flavell RA
    Proc Natl Acad Sci U S A; 1997 Apr; 94(7):3004-9. PubMed ID: 9096336
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The stress kinase mitogen-activated protein kinase kinase (MKK)7 is a negative regulator of antigen receptor and growth factor receptor-induced proliferation in hematopoietic cells.
    Sasaki T; Wada T; Kishimoto H; Irie-Sasaki J; Matsumoto G; Goto T; Yao Z; Wakeham A; Mak TW; Suzuki A; Cho SK; Zuniga-Pflucker JC; Oliveira-dos-Santos AJ; Katada T; Nishina H; Penninger JM
    J Exp Med; 2001 Sep; 194(6):757-68. PubMed ID: 11560992
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses.
    Moriguchi T; Toyoshima F; Masuyama N; Hanafusa H; Gotoh Y; Nishida E
    EMBO J; 1997 Dec; 16(23):7045-53. PubMed ID: 9384583
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression and mutation analyses of MKK4, a candidate tumour suppressor gene encoded by chromosome 17p, in human gastric adenocarcinoma.
    Chae KS; Ryu BK; Lee MG; Byun DS; Chi SG
    Eur J Cancer; 2002 Oct; 38(15):2048-57. PubMed ID: 12376211
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.