BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 12651272)

  • 1. Comparison of cytotoxicity of 2-chloro- 2'-arabino-fluoro-2'-deoxyadenosine (clofarabine) with cladribine in mononuclear cells from patients with acute myeloid and chronic lymphocytic leukemia.
    Lindemalm S; Liliemark J; Gruber A; Eriksson S; Karlsson MO; Wang Y; Albertioni F
    Haematologica; 2003 Mar; 88(3):324-32. PubMed ID: 12651272
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biochemical pharmacology and resistance to 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, a novel analogue of cladribine in human leukemic cells.
    Lotfi K; Månsson E; Spasokoukotskaja T; Pettersson B; Liliemark J; Peterson C; Eriksson S; Albertioni F
    Clin Cancer Res; 1999 Sep; 5(9):2438-44. PubMed ID: 10499616
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance.
    Månsson E; Flordal E; Liliemark J; Spasokoukotskaja T; Elford H; Lagercrantz S; Eriksson S; Albertioni F
    Biochem Pharmacol; 2003 Jan; 65(2):237-47. PubMed ID: 12504799
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kinetics and metabolism of 2-chloro-2'-deoxyadenosine and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine in the isolated perfused rat liver.
    Albertioni F; Hassan M; Silberring J; Liliemark J
    Eur J Drug Metab Pharmacokinet; 1995; 20(3):225-32. PubMed ID: 8751045
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine.
    Carson DA; Wasson DB; Esparza LM; Carrera CJ; Kipps TJ; Cottam HB
    Proc Natl Acad Sci U S A; 1992 Apr; 89(7):2970-4. PubMed ID: 1348362
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stability and analysis of 2-chloro-2'-deoxyadenosine, 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine and 2-chloroadenine in human blood plasma.
    Lindemalm S; Albertioni F; Liliemark J
    Anticancer Drugs; 1997 Jun; 8(5):445-53. PubMed ID: 9215606
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evaluation of apoptosis induced in vitro by cladribine (2-CdA) combined with anthracyclines in lymphocytes from patients with B-cell chronic lymphocytic leukemia.
    Szmigielska-Kaplon A; Smolewski P; Najder M; Robak T
    Ann Hematol; 2002 Sep; 81(9):508-13. PubMed ID: 12373351
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distribution of 2-chloro-2'-deoxyadenosine, 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, fludarabine and cytarabine in mice: a whole-body autoradiography study.
    Lindemalm S; Liliemark J; Larsson BS; Albertioni F
    Med Oncol; 1999 Dec; 16(4):239-44. PubMed ID: 10618686
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular and biochemical mechanisms of fludarabine and cladribine resistance in a human promyelocytic cell line.
    Månsson E; Spasokoukotskaja T; Sällström J; Eriksson S; Albertioni F
    Cancer Res; 1999 Dec; 59(23):5956-63. PubMed ID: 10606241
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Resistance to 2-chloro-2'-deoxyadenosine of the human B-cell leukemia cell line EHEB.
    Cardoen S; Van Den Neste E; Smal C; Rosier JF; Delacauw A; Ferrant A; Van den Berghe G; Bontemps F
    Clin Cancer Res; 2001 Nov; 7(11):3559-66. PubMed ID: 11705877
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analysis of DNA methylation of the 5' region of the deoxycytidine kinase gene in CCRF-CEM-sensitive and cladribine (CdA)- and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine (CAFdA)-resistant cells.
    Leegwater PA; De Abreu RA; Albertioni F
    Cancer Lett; 1998 Aug; 130(1-2):169-73. PubMed ID: 9751270
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro cytotoxicity of 2-chlorodeoxyadenosine and chlorambucil in chronic lymphocytic leukemia.
    Begleiter A; Wang H; Verburg L; Lee K; Israels LG; Mowat MR; Johnston JB
    Leukemia; 1996 Dec; 10(12):1959-65. PubMed ID: 8946937
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems.
    King KM; Damaraju VL; Vickers MF; Yao SY; Lang T; Tackaberry TE; Mowles DA; Ng AM; Young JD; Cass CE
    Mol Pharmacol; 2006 Jan; 69(1):346-53. PubMed ID: 16234483
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-Chloro-2'-deoxyadenosine inhibits DNA repair synthesis and potentiates UVC cytotoxicity in chronic lymphocytic leukemia B lymphocytes.
    Van Den Neste E; Cardoen S; Husson B; Rosier JF; Delacauw A; Ferrant A; Van den Berghe G; Bontemps F
    Leukemia; 2002 Jan; 16(1):36-43. PubMed ID: 11840261
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Clinical and pharmacokinetic study of clofarabine in chronic lymphocytic leukemia: strategy for treatment.
    Gandhi V; Plunkett W; Bonate PL; Du M; Nowak B; Lerner S; Keating MJ
    Clin Cancer Res; 2006 Jul; 12(13):4011-7. PubMed ID: 16818700
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparison of antitumor activities of 2-chlorodeoxyadenosine and 9-beta-arabinosyl-2-fluoroadenine in chronic lymphocytic leukemia and marrow cells in vitro.
    Begleiter A; Verburg L; Ashique A; Lee K; Israels LG; Mowat MR; Johnston JB
    Leukemia; 1995 Nov; 9(11):1875-81. PubMed ID: 7475278
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro sensitivity of chronic lymphocytic leukemia B-cells to fludarabine, 2-chlorodeoxyadenosine and chlorambucil: correlation with clinico-hematological and immunophenotypic features.
    Morabito F; Stelitano C; Callea I; Filangeri M; Oliva B; Sculli G; Callea V; Nobile F; Brugiatelli M
    Haematologica; 1996; 81(3):224-31. PubMed ID: 8767527
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria.
    Genini D; Adachi S; Chao Q; Rose DW; Carrera CJ; Cottam HB; Carson DA; Leoni LM
    Blood; 2000 Nov; 96(10):3537-43. PubMed ID: 11071652
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological inhibition of the MAPK/ERK pathway increases sensitivity to 2-chloro-2'-deoxyadenosine (CdA) in the B-cell leukemia cell line EHEB.
    Smal C; Lisart S; Maerevoet M; Ferrant A; Bontemps F; Van Den Neste E
    Biochem Pharmacol; 2007 Feb; 73(3):351-8. PubMed ID: 17137556
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bcl-2 protein expression and p53 gene mutation in chronic lymphocytic leukemia: correlation with in vitro sensitivity to chlorambucil and purine analogs.
    Morabito F; Filangeri M; Callea I; Sculli G; Callea V; Fracchiolla NS; Neri A; Brugiatelli M
    Haematologica; 1997; 82(1):16-20. PubMed ID: 9107076
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.