These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1120 related articles for article (PubMed ID: 12654264)

  • 1. Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct.
    Perlow RA; Broyde S
    J Mol Biol; 2003 Apr; 327(4):797-818. PubMed ID: 12654264
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen.
    Perlow RA; Broyde S
    J Mol Biol; 2001 Jun; 309(2):519-36. PubMed ID: 11371169
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Toward understanding the mutagenicity of an environmental carcinogen: structural insights into nucleotide incorporation preferences.
    Perlow RA; Broyde S
    J Mol Biol; 2002 Sep; 322(2):291-309. PubMed ID: 12217692
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function relationship through experimental and computational approaches.
    Perlow-Poehnelt RA; Likhterov I; Scicchitano DA; Geacintov NE; Broyde S
    J Biol Chem; 2004 Aug; 279(35):36951-61. PubMed ID: 15210693
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner.
    Perlow RA; Kolbanovskii A; Hingerty BE; Geacintov NE; Broyde S; Scicchitano DA
    J Mol Biol; 2002 Aug; 321(1):29-47. PubMed ID: 12139931
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment.
    Bauer J; Xing G; Yagi H; Sayer JM; Jerina DM; Ling H
    Proc Natl Acad Sci U S A; 2007 Sep; 104(38):14905-10. PubMed ID: 17848527
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction.
    Feng B; Gorin A; Hingerty BE; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1997 Nov; 36(45):13769-79. PubMed ID: 9374853
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis of accurate replication beyond a bulky major benzo[a]pyrene adduct by human DNA polymerase kappa.
    Jha V; Ling H
    DNA Repair (Amst); 2017 Jan; 49():43-50. PubMed ID: 27894903
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
    Feng B; Gorin A; Kolbanovskiy A; Hingerty BE; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1997 Nov; 36(45):13780-90. PubMed ID: 9374854
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex.
    Mao B; Gu Z; Gorin A; Chen J; Hingerty BE; Amin S; Broyde S; Geacintov NE; Patel DJ
    Biochemistry; 1999 Aug; 38(33):10831-42. PubMed ID: 10451380
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Solution structures of aminofluorene [AF]-stacked conformers of the syn [AF]-C8-dG adduct positioned opposite dC or dA at a template-primer junction.
    Gu Z; Gorin A; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1999 Aug; 38(33):10855-70. PubMed ID: 10451382
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interactions between DNA polymerase beta and the major covalent adduct of the carcinogen (+)-anti-benzo[a]pyrene diol epoxide with DNA at a primer-template junction.
    Singh SB; Beard WA; Hingerty BE; Wilson SH; Broyde S
    Biochemistry; 1998 Jan; 37(3):878-84. PubMed ID: 9454577
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Solution conformation of the (+)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the major groove.
    Cosman M; Fiala R; Hingerty BE; Amin S; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1994 Sep; 33(38):11507-17. PubMed ID: 7918364
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular dynamics of a food carcinogen-DNA adduct in a replicative DNA polymerase suggest hindered nucleotide incorporation and extension.
    Zhang L; Shapiro R; Broyde S
    Chem Res Toxicol; 2005 Sep; 18(9):1347-63. PubMed ID: 16167826
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Solution conformation of the (+)-cis-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
    Cosman M; Fiala R; Hingerty BE; Amin S; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1994 Sep; 33(38):11518-27. PubMed ID: 7918365
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove.
    Cosman M; Hingerty BE; Luneva N; Amin S; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1996 Jul; 35(30):9850-63. PubMed ID: 8703959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural alignments of (+)- and (-)-trans-anti-benzo[a]pyrene-dG adducts positioned at a DNA template-primer junction.
    Cosman M; Hingerty BE; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1995 Nov; 34(46):15334-50. PubMed ID: 7578150
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Altering DNA polymerase incorporation fidelity by distorting the dNTP binding pocket with a bulky carcinogen-damaged template.
    Yan SF; Wu M; Geacintov NE; Broyde S
    Biochemistry; 2004 Jun; 43(24):7750-65. PubMed ID: 15196018
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural characterization of a (+)-trans-anti-benzo[a]pyrene-DNA adduct using NMR, restrained energy minimization, and molecular dynamics.
    Fountain MA; Krugh TR
    Biochemistry; 1995 Mar; 34(10):3152-61. PubMed ID: 7880810
    [TBL] [Abstract][Full Text] [Related]  

  • 20. trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases.
    Rechkoblit O; Zhang Y; Guo D; Wang Z; Amin S; Krzeminsky J; Louneva N; Geacintov NE
    J Biol Chem; 2002 Aug; 277(34):30488-94. PubMed ID: 12063247
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 56.