BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 12657270)

  • 1. Structure-activity relationship of cyclic peptide penta-c[Asp-His(6)-DPhe(7)-Arg(8)-Trp(9)-Lys]-NH(2) at the human melanocortin-1 and -4 receptors: His(6) substitution.
    Cheung AW; Danho W; Swistok J; Qi L; Kurylko G; Rowan K; Yeon M; Franco L; Chu XJ; Chen L; Yagaloff K
    Bioorg Med Chem Lett; 2003 Apr; 13(7):1307-11. PubMed ID: 12657270
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationship of linear peptide Bu-His-DPhe-Arg-Trp-Gly-NH(2) at the human melanocortin-1 and -4 receptors: histidine substitution.
    Cheung AW; Danho W; Swistok J; Qi L; Kurylko G; Rowan K; Yeon M; Franco L; Chu XJ; Chen L; Yagaloff K
    Bioorg Med Chem Lett; 2003 Jan; 13(1):133-7. PubMed ID: 12467633
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of highly potent and selective melanotropin analogues of SHU9119 modified at position 6.
    Grieco P; Han G; Weinberg D; Van der Ploeg LH; Hruby VJ
    Biochem Biophys Res Commun; 2002 Apr; 292(4):1075-80. PubMed ID: 11944925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships of the unique and potent agouti-related protein (AGRP)-melanocortin chimeric Tyr-c[beta-Asp-His-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH2 peptide template.
    Wilczynski A; Wilson KR; Scott JW; Edison AS; Haskell-Luevano C
    J Med Chem; 2005 Apr; 48(8):3060-75. PubMed ID: 15828845
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors.
    Haskell-Luevano C; Nikiforovich G; Sharma SD; Yang YK; Dickinson C; Hruby VJ; Gantz I
    J Med Chem; 1997 May; 40(11):1738-48. PubMed ID: 9171884
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Extensive structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5.
    Grieco P; Balse-Srinivasan P; Han G; Weinberg D; MacNeil T; Van der Ploeg LH; Hruby VJ
    J Pept Res; 2003 Nov; 62(5):199-206. PubMed ID: 14531843
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationship of linear peptide Bu-His-DPhe-Arg-Trp-Gly-NH(2) at the human melanocortin-1 and -4 receptors: arginine substitution.
    Cheung AW; Danho W; Swistok J; Qi L; Kurylko G; Franco L; Yagaloff K; Chen L
    Bioorg Med Chem Lett; 2002 Sep; 12(17):2407-10. PubMed ID: 12161144
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors. 1. Modifications at the His position.
    Holder JR; Bauzo RM; Xiang Z; Haskell-Luevano C
    J Med Chem; 2002 Jun; 45(13):2801-10. PubMed ID: 12061882
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-activity relationships of gamma-MSH analogues at the human melanocortin MC3, MC4, and MC5 receptors. Discovery of highly selective hMC3R, hMC4R, and hMC5R analogues.
    Balse-Srinivasan P; Grieco P; Cai M; Trivedi D; Hruby VJ
    J Med Chem; 2003 Nov; 46(23):4965-73. PubMed ID: 14584947
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R.
    Haskell-Luevano C; Hendrata S; North C; Sawyer TK; Hadley ME; Hruby VJ; Dickinson C; Gantz I
    J Med Chem; 1997 Jul; 40(14):2133-9. PubMed ID: 9216831
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors: part 2 modifications at the Phe position.
    Holder JR; Bauzo RM; Xiang Z; Haskell-Luevano C
    J Med Chem; 2002 Jul; 45(14):3073-81. PubMed ID: 12086493
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5.
    Grieco P; Cai M; Han G; Trivedi D; Campiglia P; Novellino E; Hruby VJ
    Peptides; 2007 Jun; 28(6):1191-6. PubMed ID: 17482720
    [TBL] [Abstract][Full Text] [Related]  

  • 13. De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach.
    Han G; Haskell-Luevano C; Kendall L; Bonner G; Hadley ME; Cone RD; Hruby VJ
    J Med Chem; 2004 Mar; 47(6):1514-26. PubMed ID: 14998337
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R.
    Balse-Srinivasan P; Grieco P; Cai M; Trivedi D; Hruby VJ
    J Med Chem; 2003 Aug; 46(17):3728-33. PubMed ID: 12904077
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity studies of the melanocortin peptides: discovery of potent and selective affinity antagonists for the hMC3 and hMC4 receptors.
    Grieco P; Lavecchia A; Cai M; Trivedi D; Weinberg D; MacNeil T; Van der Ploeg LH; Hruby VJ
    J Med Chem; 2002 Nov; 45(24):5287-94. PubMed ID: 12431055
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chimeric NDP-MSH and MTII melanocortin peptides with agouti-related protein (AGRP) Arg-Phe-Phe amino acids possess agonist melanocortin receptor activity.
    Joseph CG; Wilczynski A; Holder JR; Xiang Z; Bauzo RM; Scott JW; Haskell-Luevano C
    Peptides; 2003 Dec; 24(12):1899-908. PubMed ID: 15127941
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A predictive pharmacophore model of human melanocortin-4 receptor as derived from the solution structures of cyclic peptides.
    Sun H; Greeley DN; Chu XJ; Cheung A; Danho W; Swistok J; Wang Y; Zhao C; Chen L; Fry DC
    Bioorg Med Chem; 2004 May; 12(10):2671-7. PubMed ID: 15110848
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C
    J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel selective human melanocortin-3 receptor ligands: use of the 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one (Aba) scaffold.
    Ballet S; Mayorov AV; Cai M; Tymecka D; Chandler KB; Palmer ES; Rompaey KV; Misicka A; Tourwé D; Hruby VJ
    Bioorg Med Chem Lett; 2007 May; 17(9):2492-8. PubMed ID: 17314042
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Potent and selective agonists of human melanocortin receptor 5: cyclic analogues of alpha-melanocyte-stimulating hormone.
    Bednarek MA; MacNeil T; Tang R; Fong TM; Cabello MA; Maroto M; Teran A
    J Med Chem; 2007 May; 50(10):2520-6. PubMed ID: 17455928
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.