These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 12657276)

  • 1. Inhibition of telomerase by BIBR 1532 and related analogues.
    Barma DK; Elayadi A; Falck JR; Corey DR
    Bioorg Med Chem Lett; 2003 Apr; 13(7):1333-6. PubMed ID: 12657276
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A new strategy for detection and development of tractable telomerase inhibitors.
    Cohn EP; Wu KL; Pettus TR; Reich NO
    J Med Chem; 2012 Apr; 55(8):3678-86. PubMed ID: 22413845
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and SARs of novel telomerase inhibitors based on BIBR1532.
    Liu C; Zhou H; Sheng XB; Liu XH; Chen FH
    Bioorg Chem; 2020 Sep; 102():104077. PubMed ID: 32682156
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of human telomerase inhibition by BIBR1532, a synthetic, non-nucleosidic drug candidate.
    Pascolo E; Wenz C; Lingner J; Hauel N; Priepke H; Kauffmann I; Garin-Chesa P; Rettig WJ; Damm K; Schnapp A
    J Biol Chem; 2002 May; 277(18):15566-72. PubMed ID: 11854300
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Short-term inhibition of TERT induces telomere length-independent cell cycle arrest and apoptotic response in EBV-immortalized and transformed B cells.
    Celeghin A; Giunco S; Freguja R; Zangrossi M; Nalio S; Dolcetti R; De Rossi A
    Cell Death Dis; 2016 Dec; 7(12):e2562. PubMed ID: 28032863
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Optimization of the TRAP assay to evaluate specificity of telomerase inhibitors.
    Piotrowska K; Kleideiter E; Mürdter TE; Taetz S; Baldes C; Schaefer U; Lehr CM; Klotz U
    Lab Invest; 2005 Dec; 85(12):1565-9. PubMed ID: 16170334
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase.
    Perry PJ; Gowan SM; Reszka AP; Polucci P; Jenkins TC; Kelland LR; Neidle S
    J Med Chem; 1998 Aug; 41(17):3253-60. PubMed ID: 9703471
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New prospects for targeting telomerase beyond the telomere.
    Arndt GM; MacKenzie KL
    Nat Rev Cancer; 2016 Aug; 16(8):508-24. PubMed ID: 27339602
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-based design, synthesis and evaluation of novel anthra[1,2-d]imidazole-6,11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacology.
    Chen CL; Chang DM; Chen TC; Lee CC; Hsieh HH; Huang FC; Huang KF; Guh JH; Lin JJ; Huang HS
    Eur J Med Chem; 2013 Feb; 60():29-41. PubMed ID: 23279865
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and evaluation of human telomerase inhibitors based upon a tetracyclic structural motif.
    Perry PJ; Gowan SM; Read MA; Kelland LR; Neidle S
    Anticancer Drug Des; 1999 Aug; 14(4):373-82. PubMed ID: 10625930
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of human telomerase activity by antisense phosphorothioate oligonucleotides encapsulated with the transfection reagent, FuGENE6, in HeLa cells.
    Tamura Y; Tao M; Miyano-Kurosaki N; Takai K; Takaku H
    Antisense Nucleic Acid Drug Dev; 2000 Apr; 10(2):87-96. PubMed ID: 10805159
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural Basis of Telomerase Inhibition by the Highly Specific BIBR1532.
    Bryan C; Rice C; Hoffman H; Harkisheimer M; Sweeney M; Skordalakes E
    Structure; 2015 Oct; 23(10):1934-1942. PubMed ID: 26365799
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quadruplex-interactive agents as telomerase inhibitors: synthesis of porphyrins and structure-activity relationship for the inhibition of telomerase.
    Shi DF; Wheelhouse RT; Sun D; Hurley LH
    J Med Chem; 2001 Dec; 44(26):4509-23. PubMed ID: 11741471
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and biological evaluation of heterocyclic azoles derivatives containing pyrazine moiety as potential telomerase inhibitors.
    Zhang YB; Wang XL; Liu W; Yang YS; Tang JF; Zhu HL
    Bioorg Med Chem; 2012 Nov; 20(21):6356-65. PubMed ID: 23018096
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of novel 2-methyl-4,5-substitutedbenzo[f]-3,3a,4,5-tetrahydro-pyrazolo[1,5-d][1,4]oxazepin-8(7H)-one derivatives as telomerase inhibitors.
    Liu XH; Jia YM; Song BA; Pang ZX; Yang S
    Bioorg Med Chem Lett; 2013 Feb; 23(3):720-3. PubMed ID: 23265905
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Screening of telomerase inhibitors.
    Kleideiter E; Piotrowska K; Klotz U
    Methods Mol Biol; 2007; 405():167-80. PubMed ID: 18369824
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of novel telomerase inhibitors based on a bisindole unit.
    Sasaki S; Ehara T; Sakata I; Fujino Y; Harada N; Kimura J; Nakamura H; Maeda M
    Bioorg Med Chem Lett; 2001 Feb; 11(4):583-5. PubMed ID: 11229776
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of human telomerase activity by peptide nucleic acids.
    Norton JC; Piatyszek MA; Wright WE; Shay JW; Corey DR
    Nat Biotechnol; 1996 May; 14(5):615-9. PubMed ID: 9630953
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Shikonin derivatives: synthesis and inhibition of human telomerase.
    Lu Q; Liu W; Ding J; Cai J; Duan W
    Bioorg Med Chem Lett; 2002 May; 12(10):1375-8. PubMed ID: 11992780
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, biological evaluation, 3D-QSAR studies of novel aryl-2H-pyrazole derivatives as telomerase inhibitors.
    Luo Y; Zhang S; Qiu KM; Liu ZJ; Yang YS; Fu J; Zhong WQ; Zhu HL
    Bioorg Med Chem Lett; 2013 Feb; 23(4):1091-5. PubMed ID: 23312949
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.