These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

344 related articles for article (PubMed ID: 12657655)

  • 1. Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.
    Marr RA; Rockenstein E; Mukherjee A; Kindy MS; Hersh LB; Gage FH; Verma IM; Masliah E
    J Neurosci; 2003 Mar; 23(6):1992-6. PubMed ID: 12657655
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice.
    Spencer B; Marr RA; Rockenstein E; Crews L; Adame A; Potkar R; Patrick C; Gage FH; Verma IM; Masliah E
    BMC Neurosci; 2008 Nov; 9():109. PubMed ID: 19014502
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neprilysin regulates amyloid Beta peptide levels.
    Marr RA; Guan H; Rockenstein E; Kindy M; Gage FH; Verma I; Masliah E; Hersh LB
    J Mol Neurosci; 2004; 22(1-2):5-11. PubMed ID: 14742905
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Recombinant soluble neprilysin reduces amyloid-beta accumulation and improves memory impairment in Alzheimer's disease mice.
    Park MH; Lee JK; Choi S; Ahn J; Jin HK; Park JS; Bae JS
    Brain Res; 2013 Sep; 1529():113-24. PubMed ID: 23831521
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain.
    Iwata N; Mizukami H; Shirotani K; Takaki Y; Muramatsu S; Lu B; Gerard NP; Gerard C; Ozawa K; Saido TC
    J Neurosci; 2004 Jan; 24(4):991-8. PubMed ID: 14749444
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease.
    El-Amouri SS; Zhu H; Yu J; Marr R; Verma IM; Kindy MS
    Am J Pathol; 2008 May; 172(5):1342-54. PubMed ID: 18403590
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neprilysin deficiency alters the neuropathological and behavioral phenotype in the 5XFAD mouse model of Alzheimer's disease.
    Hüttenrauch M; Baches S; Gerth J; Bayer TA; Weggen S; Wirths O
    J Alzheimers Dis; 2015; 44(4):1291-302. PubMed ID: 25408216
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.
    Hemming ML; Patterson M; Reske-Nielsen C; Lin L; Isacson O; Selkoe DJ
    PLoS Med; 2007 Aug; 4(8):e262. PubMed ID: 17760499
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intracranial injection of AAV expressing NEP but not IDE reduces amyloid pathology in APP+PS1 transgenic mice.
    Carty N; Nash KR; Brownlow M; Cruite D; Wilcock D; Selenica ML; Lee DC; Gordon MN; Morgan D
    PLoS One; 2013; 8(3):e59626. PubMed ID: 23555730
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy.
    Farris W; Schütz SG; Cirrito JR; Shankar GM; Sun X; George A; Leissring MA; Walsh DM; Qiu WQ; Holtzman DM; Selkoe DJ
    Am J Pathol; 2007 Jul; 171(1):241-51. PubMed ID: 17591969
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology.
    Fukami S; Watanabe K; Iwata N; Haraoka J; Lu B; Gerard NP; Gerard C; Fraser P; Westaway D; St George-Hyslop P; Saido TC
    Neurosci Res; 2002 May; 43(1):39-56. PubMed ID: 12074840
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.
    Rockenstein E; Torrance M; Mante M; Adame A; Paulino A; Rose JB; Crews L; Moessler H; Masliah E
    J Neurosci Res; 2006 May; 83(7):1252-61. PubMed ID: 16511867
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice.
    Meilandt WJ; Cisse M; Ho K; Wu T; Esposito LA; Scearce-Levie K; Cheng IH; Yu GQ; Mucke L
    J Neurosci; 2009 Feb; 29(7):1977-86. PubMed ID: 19228952
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease.
    Rose JB; Crews L; Rockenstein E; Adame A; Mante M; Hersh LB; Gage FH; Spencer B; Potkar R; Marr RA; Masliah E
    J Neurosci; 2009 Jan; 29(4):1115-25. PubMed ID: 19176820
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neprilysin protects neurons against Abeta peptide toxicity.
    El-Amouri SS; Zhu H; Yu J; Gage FH; Verma IM; Kindy MS
    Brain Res; 2007 Jun; 1152():191-200. PubMed ID: 17459354
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Overexpression of neprilysin reduces alzheimer amyloid-beta42 (Abeta42)-induced neuron loss and intraneuronal Abeta42 deposits but causes a reduction in cAMP-responsive element-binding protein-mediated transcription, age-dependent axon pathology, and premature death in Drosophila.
    Iijima-Ando K; Hearn SA; Granger L; Shenton C; Gatt A; Chiang HC; Hakker I; Zhong Y; Iijima K
    J Biol Chem; 2008 Jul; 283(27):19066-76. PubMed ID: 18463098
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A PPARdelta agonist reduces amyloid burden and brain inflammation in a transgenic mouse model of Alzheimer's disease.
    Kalinin S; Richardson JC; Feinstein DL
    Curr Alzheimer Res; 2009 Oct; 6(5):431-7. PubMed ID: 19874267
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer's disease.
    Klein C; Roussel G; Brun S; Rusu C; Patte-Mensah C; Maitre M; Mensah-Nyagan AG
    Acta Neuropathol Commun; 2018 Dec; 6(1):136. PubMed ID: 30537985
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Peripherally expressed neprilysin reduces brain amyloid burden: a novel approach for treating Alzheimer's disease.
    Guan H; Liu Y; Daily A; Police S; Kim MH; Oddo S; LaFerla FM; Pauly JR; Murphy MP; Hersh LB
    J Neurosci Res; 2009 May; 87(6):1462-73. PubMed ID: 19021293
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Self-assembling nanofibers alter the processing of amyloid precursor protein in a transgenic mouse model of Alzheimer's disease.
    Yang H; Yang H; Xie Z; Wang P; Bi J
    Neurol Res; 2015 Jan; 37(1):84-91. PubMed ID: 25005263
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.