593 related articles for article (PubMed ID: 12660252)
1. Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.
Furuta T; Takemura H; Liao ZY; Aune GJ; Redon C; Sedelnikova OA; Pilch DR; Rogakou EP; Celeste A; Chen HT; Nussenzweig A; Aladjem MI; Bonner WM; Pommier Y
J Biol Chem; 2003 May; 278(22):20303-12. PubMed ID: 12660252
[TBL] [Abstract][Full Text] [Related]
2. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
[TBL] [Abstract][Full Text] [Related]
3. Hedamycin, a DNA alkylator, induces (gamma)H2AX and chromosome aberrations: involvement of phosphatidylinositol 3-kinase-related kinases and DNA replication fork movement.
Tu LC; Matsui SI; Beerman TA
Mol Cancer Ther; 2005 Aug; 4(8):1175-85. PubMed ID: 16093433
[TBL] [Abstract][Full Text] [Related]
4. p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.
Furuta T; Hayward RL; Meng LH; Takemura H; Aune GJ; Bonner WM; Aladjem MI; Kohn KW; Pommier Y
Oncogene; 2006 May; 25(20):2839-49. PubMed ID: 16407843
[TBL] [Abstract][Full Text] [Related]
5. Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage.
Rao VA; Fan AM; Meng L; Doe CF; North PS; Hickson ID; Pommier Y
Mol Cell Biol; 2005 Oct; 25(20):8925-37. PubMed ID: 16199871
[TBL] [Abstract][Full Text] [Related]
6. ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
Ewald B; Sampath D; Plunkett W
Cancer Res; 2008 Oct; 68(19):7947-55. PubMed ID: 18829552
[TBL] [Abstract][Full Text] [Related]
7. Induction of biphasic DNA double strand breaks and activation of multiple repair protein complexes by DNA topoisomerase I drug 7-ethyl-10-hydroxy-camptothecin.
Wu J; Yin MB; Hapke G; Tóth K; Rustum YM
Mol Pharmacol; 2002 Apr; 61(4):742-8. PubMed ID: 11901212
[TBL] [Abstract][Full Text] [Related]
8. Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks.
Sordet O; Redon CE; Guirouilh-Barbat J; Smith S; Solier S; Douarre C; Conti C; Nakamura AJ; Das BB; Nicolas E; Kohn KW; Bonner WM; Pommier Y
EMBO Rep; 2009 Aug; 10(8):887-93. PubMed ID: 19557000
[TBL] [Abstract][Full Text] [Related]
9. Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks.
Robison JG; Elliott J; Dixon K; Oakley GG
J Biol Chem; 2004 Aug; 279(33):34802-10. PubMed ID: 15180989
[TBL] [Abstract][Full Text] [Related]
10. Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes.
Lee JH; Ghirlando R; Bhaskara V; Hoffmeyer MR; Gu J; Paull TT
J Biol Chem; 2003 Nov; 278(46):45171-81. PubMed ID: 12966088
[TBL] [Abstract][Full Text] [Related]
11. Intracellular redistribution and modification of proteins of the Mre11/Rad50/Nbs1 DNA repair complex following irradiation and heat-shock.
Seno JD; Dynlacht JR
J Cell Physiol; 2004 May; 199(2):157-70. PubMed ID: 15039997
[TBL] [Abstract][Full Text] [Related]
12. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage.
Paull TT; Rogakou EP; Yamazaki V; Kirchgessner CU; Gellert M; Bonner WM
Curr Biol; 2000 Jul 27-Aug 10; 10(15):886-95. PubMed ID: 10959836
[TBL] [Abstract][Full Text] [Related]
13. Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes.
Shao RG; Cao CX; Zhang H; Kohn KW; Wold MS; Pommier Y
EMBO J; 1999 Mar; 18(5):1397-406. PubMed ID: 10064605
[TBL] [Abstract][Full Text] [Related]
14. Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks.
Rybak P; Hoang A; Bujnowicz L; Bernas T; Berniak K; Zarębski M; Darzynkiewicz Z; Dobrucki J
Oncotarget; 2016 Aug; 7(31):49574-49587. PubMed ID: 27391338
[TBL] [Abstract][Full Text] [Related]
15. Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff.
Strumberg D; Pilon AA; Smith M; Hickey R; Malkas L; Pommier Y
Mol Cell Biol; 2000 Jun; 20(11):3977-87. PubMed ID: 10805740
[TBL] [Abstract][Full Text] [Related]
16. Widespread phosphorylation of histone H2AX by species C adenovirus infection requires viral DNA replication.
Nichols GJ; Schaack J; Ornelles DA
J Virol; 2009 Jun; 83(12):5987-98. PubMed ID: 19321613
[TBL] [Abstract][Full Text] [Related]
17. The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks.
Nakamura AJ; Rao VA; Pommier Y; Bonner WM
Cell Cycle; 2010 Jan; 9(2):389-97. PubMed ID: 20046100
[TBL] [Abstract][Full Text] [Related]
18. ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.
Jossé R; Martin SE; Guha R; Ormanoglu P; Pfister TD; Reaper PM; Barnes CS; Jones J; Charlton P; Pollard JR; Morris J; Doroshow JH; Pommier Y
Cancer Res; 2014 Dec; 74(23):6968-79. PubMed ID: 25269479
[TBL] [Abstract][Full Text] [Related]
19. Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complex.
Guirouilh-Barbat J; Redon C; Pommier Y
Mol Biol Cell; 2008 Sep; 19(9):3969-81. PubMed ID: 18632984
[TBL] [Abstract][Full Text] [Related]
20. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex.
Lee JH; Paull TT
Science; 2004 Apr; 304(5667):93-6. PubMed ID: 15064416
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
