195 related articles for article (PubMed ID: 12663673)
1. Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation.
Drisaldi B; Stewart RS; Adles C; Stewart LR; Quaglio E; Biasini E; Fioriti L; Chiesa R; Harris DA
J Biol Chem; 2003 Jun; 278(24):21732-43. PubMed ID: 12663673
[TBL] [Abstract][Full Text] [Related]
2. Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations.
Fioriti L; Dossena S; Stewart LR; Stewart RS; Harris DA; Forloni G; Chiesa R
J Biol Chem; 2005 Mar; 280(12):11320-8. PubMed ID: 15632159
[TBL] [Abstract][Full Text] [Related]
3. A transmembrane form of the prion protein contains an uncleaved signal peptide and is retained in the endoplasmic Reticulum.
Stewart RS; Drisaldi B; Harris DA
Mol Biol Cell; 2001 Apr; 12(4):881-9. PubMed ID: 11294893
[TBL] [Abstract][Full Text] [Related]
4. Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein.
Yedidia Y; Horonchik L; Tzaban S; Yanai A; Taraboulos A
EMBO J; 2001 Oct; 20(19):5383-91. PubMed ID: 11574470
[TBL] [Abstract][Full Text] [Related]
5. Expression of mutant or cytosolic PrP in transgenic mice and cells is not associated with endoplasmic reticulum stress or proteasome dysfunction.
Quaglio E; Restelli E; Garofoli A; Dossena S; De Luigi A; Tagliavacca L; Imperiale D; Migheli A; Salmona M; Sitia R; Forloni G; Chiesa R
PLoS One; 2011 Apr; 6(4):e19339. PubMed ID: 21559407
[TBL] [Abstract][Full Text] [Related]
6. Proteasomal degradation and N-terminal protease resistance of the codon 145 mutant prion protein.
Zanusso G; Petersen RB; Jin T; Jing Y; Kanoush R; Ferrari S; Gambetti P; Singh N
J Biol Chem; 1999 Aug; 274(33):23396-404. PubMed ID: 10438517
[TBL] [Abstract][Full Text] [Related]
7. Aggresome formation by mutant prion proteins: the unfolding role of proteasomes in familial prion disorders.
Mishra RS; Bose S; Gu Y; Li R; Singh N
J Alzheimers Dis; 2003 Feb; 5(1):15-23. PubMed ID: 12590162
[TBL] [Abstract][Full Text] [Related]
8. The chaperone protein BiP binds to a mutant prion protein and mediates its degradation by the proteasome.
Jin T; Gu Y; Zanusso G; Sy M; Kumar A; Cohen M; Gambetti P; Singh N
J Biol Chem; 2000 Dec; 275(49):38699-704. PubMed ID: 10970892
[TBL] [Abstract][Full Text] [Related]
9. A novel quality control compartment derived from the endoplasmic reticulum.
Kamhi-Nesher S; Shenkman M; Tolchinsky S; Fromm SV; Ehrlich R; Lederkremer GZ
Mol Biol Cell; 2001 Jun; 12(6):1711-23. PubMed ID: 11408579
[TBL] [Abstract][Full Text] [Related]
10. The proteasome participates in degradation of mutant alpha 1-antitrypsin Z in the endoplasmic reticulum of hepatoma-derived hepatocytes.
Teckman JH; Burrows J; Hidvegi T; Schmidt B; Hale PD; Perlmutter DH
J Biol Chem; 2001 Nov; 276(48):44865-72. PubMed ID: 11577074
[TBL] [Abstract][Full Text] [Related]
11. Retrotranslocation of prion proteins from the endoplasmic reticulum by preventing GPI signal transamidation.
Ashok A; Hegde RS
Mol Biol Cell; 2008 Aug; 19(8):3463-76. PubMed ID: 18508914
[TBL] [Abstract][Full Text] [Related]
12. The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary.
Bebök Z; Mazzochi C; King SA; Hong JS; Sorscher EJ
J Biol Chem; 1998 Nov; 273(45):29873-8. PubMed ID: 9792704
[TBL] [Abstract][Full Text] [Related]
13. Familial prion protein mutants inhibit Hrd1-mediated retrotranslocation of misfolded proteins by depleting misfolded protein sensor BiP.
Peters SL; Déry MA; LeBlanc AC
Hum Mol Genet; 2016 Mar; 25(5):976-88. PubMed ID: 26740554
[TBL] [Abstract][Full Text] [Related]
14. Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome.
Hughes EA; Hammond C; Cresswell P
Proc Natl Acad Sci U S A; 1997 Mar; 94(5):1896-901. PubMed ID: 9050876
[TBL] [Abstract][Full Text] [Related]
15. Degradation of wild-type vasopressin precursor and pathogenic mutants by the proteasome.
Friberg MA; Spiess M; Rutishauser J
J Biol Chem; 2004 May; 279(19):19441-7. PubMed ID: 14996841
[TBL] [Abstract][Full Text] [Related]
16. The C-terminal globular domain of the prion protein is necessary and sufficient for import into the endoplasmic reticulum.
Heske J; Heller U; Winklhofer KF; Tatzelt J
J Biol Chem; 2004 Feb; 279(7):5435-43. PubMed ID: 14645231
[TBL] [Abstract][Full Text] [Related]
17. [Scrapie, proteasome and endoplasmic reticulum].
Béranger F; Mangé A; Lehmann S
Med Sci (Paris); 2003; 19(8-9):778-80. PubMed ID: 14593603
[No Abstract] [Full Text] [Related]
18. Selective processing and metabolism of disease-causing mutant prion proteins.
Ashok A; Hegde RS
PLoS Pathog; 2009 Jun; 5(6):e1000479. PubMed ID: 19543376
[TBL] [Abstract][Full Text] [Related]
19. Efficient glycosylation site utilization by intracellular apolipoprotein B. Implications for proteasomal degradation.
Huang XF; Shelness GS
J Lipid Res; 1999 Dec; 40(12):2212-22. PubMed ID: 10588947
[TBL] [Abstract][Full Text] [Related]
20. Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation.
Ma J; Lindquist S
Proc Natl Acad Sci U S A; 2001 Dec; 98(26):14955-60. PubMed ID: 11742063
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]