BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

425 related articles for article (PubMed ID: 12673208)

  • 1. Synergistic induction of tumor cell apoptosis by death receptor antibody and chemotherapy agent through JNK/p38 and mitochondrial death pathway.
    Ohtsuka T; Buchsbaum D; Oliver P; Makhija S; Kimberly R; Zhou T
    Oncogene; 2003 Apr; 22(13):2034-44. PubMed ID: 12673208
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bisindolylmaleimide VIII enhances DR5-mediated apoptosis through the MKK4/JNK/p38 kinase and the mitochondrial pathways.
    Ohtsuka T; Zhou T
    J Biol Chem; 2002 Aug; 277(32):29294-303. PubMed ID: 12034736
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemotherapeutic agents sensitize sarcoma cell lines to tumor necrosis factor-related apoptosis-inducing ligand-induced caspase-8 activation, apoptosis and loss of mitochondrial membrane potential.
    Hotta T; Suzuki H; Nagai S; Yamamoto K; Imakiire A; Takada E; Itoh M; Mizuguchi J
    J Orthop Res; 2003 Sep; 21(5):949-57. PubMed ID: 12919886
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop.
    von Haefen C; Wieder T; Essmann F; Schulze-Osthoff K; Dörken B; Daniel PT
    Oncogene; 2003 Apr; 22(15):2236-47. PubMed ID: 12700660
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.
    Yu C; Krystal G; Varticovksi L; McKinstry R; Rahmani M; Dent P; Grant S
    Cancer Res; 2002 Jan; 62(1):188-99. PubMed ID: 11782377
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis.
    Saeki K; Kobayashi N; Inazawa Y; Zhang H; Nishitoh H; Ichijo H; Saeki K; Isemura M; Yuo A
    Biochem J; 2002 Dec; 368(Pt 3):705-20. PubMed ID: 12206715
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of JNK signaling diminishes early but not late cellular stress-induced apoptosis.
    Krilleke D; Ucur E; Pulte D; Schulze-Osthoff K; Debatin KM; Herr I
    Int J Cancer; 2003 Nov; 107(4):520-7. PubMed ID: 14520687
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
    Söderström TS; Poukkula M; Holmström TH; Heiskanen KM; Eriksson JE
    J Immunol; 2002 Sep; 169(6):2851-60. PubMed ID: 12218097
    [TBL] [Abstract][Full Text] [Related]  

  • 9. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors.
    Shenoy K; Wu Y; Pervaiz S
    Cancer Res; 2009 Mar; 69(5):1941-50. PubMed ID: 19223550
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2.
    Selimovic D; Hassan M; Haikel Y; Hengge UR
    Cell Signal; 2008 Feb; 20(2):311-22. PubMed ID: 18068334
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells.
    Stadheim TA; Xiao H; Eastman A
    Cancer Res; 2001 Feb; 61(4):1533-40. PubMed ID: 11245462
    [TBL] [Abstract][Full Text] [Related]  

  • 12. c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade.
    Desbiens KM; Deschesnes RG; Labrie MM; Desfossés Y; Lambert H; Landry J; Bellmann K
    Biochem J; 2003 Jun; 372(Pt 2):631-41. PubMed ID: 12646044
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium.
    Chuang SM; Wang IC; Yang JL
    Carcinogenesis; 2000 Jul; 21(7):1423-32. PubMed ID: 10874022
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synergy is achieved by complementation with Apo2L/TRAIL and actinomycin D in Apo2L/TRAIL-mediated apoptosis of prostate cancer cells: role of XIAP in resistance.
    Ng CP; Zisman A; Bonavida B
    Prostate; 2002 Dec; 53(4):286-99. PubMed ID: 12430140
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of MAP kinases and their cross-talk in TGF-beta1-induced apoptosis in FaO rat hepatoma cell line.
    Park HJ; Kim BC; Kim SJ; Choi KS
    Hepatology; 2002 Jun; 35(6):1360-71. PubMed ID: 12029621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation.
    MacFarlane M; Cohen GM; Dickens M
    Biochem J; 2000 May; 348 Pt 1(Pt 1):93-101. PubMed ID: 10794718
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells.
    Stone AA; Chambers TC
    Exp Cell Res; 2000 Jan; 254(1):110-9. PubMed ID: 10623471
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells.
    Cuello M; Ettenberg SA; Nau MM; Lipkowitz S
    Gynecol Oncol; 2001 Jun; 81(3):380-90. PubMed ID: 11371126
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1.
    Sheikh MS; Antinore MJ; Huang Y; Fornace AJ
    Oncogene; 1998 Nov; 17(20):2555-63. PubMed ID: 9840918
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib.
    Yu C; Rahmani M; Dent P; Grant S
    Exp Cell Res; 2004 May; 295(2):555-66. PubMed ID: 15093752
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.