167 related articles for article (PubMed ID: 12676982)
1. Evolution of an organophosphate-degrading enzyme: a comparison of natural and directed evolution.
Yang H; Carr PD; McLoughlin SY; Liu JW; Horne I; Qiu X; Jeffries CM; Russell RJ; Oakeshott JG; Ollis DL
Protein Eng; 2003 Feb; 16(2):135-45. PubMed ID: 12676982
[TBL] [Abstract][Full Text] [Related]
2. The organophosphate-degrading enzyme from Agrobacterium radiobacter displays mechanistic flexibility for catalysis.
Ely F; Hadler KS; Gahan LR; Guddat LW; Ollis DL; Schenk G
Biochem J; 2010 Dec; 432(3):565-73. PubMed ID: 20868365
[TBL] [Abstract][Full Text] [Related]
3. Functional effects of amino acid substitutions within the large binding pocket of the phosphotriesterase OpdA from Agrobacterium sp. P230.
Horne I; Qiu X; Ollis DL; Russell RJ; Oakeshott JG
FEMS Microbiol Lett; 2006 Jun; 259(2):187-94. PubMed ID: 16734778
[TBL] [Abstract][Full Text] [Related]
4. Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH).
Pedroso MM; Ely F; Mitić N; Carpenter MC; Gahan LR; Wilcox DE; Larrabee JL; Ollis DL; Schenk G
J Biol Inorg Chem; 2014 Dec; 19(8):1263-75. PubMed ID: 25104333
[TBL] [Abstract][Full Text] [Related]
5. Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans.
Hawwa R; Larsen SD; Ratia K; Mesecar AD
J Mol Biol; 2009 Oct; 393(1):36-57. PubMed ID: 19631223
[TBL] [Abstract][Full Text] [Related]
6. The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism.
Jackson C; Kim HK; Carr PD; Liu JW; Ollis DL
Biochim Biophys Acta; 2005 Aug; 1752(1):56-64. PubMed ID: 16054447
[TBL] [Abstract][Full Text] [Related]
7. Identification of an opd (organophosphate degradation) gene in an Agrobacterium isolate.
Horne I; Sutherland TD; Harcourt RL; Russell RJ; Oakeshott JG
Appl Environ Microbiol; 2002 Jul; 68(7):3371-6. PubMed ID: 12089017
[TBL] [Abstract][Full Text] [Related]
8. Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template.
Meier MM; Rajendran C; Malisi C; Fox NG; Xu C; Schlee S; Barondeau DP; Höcker B; Sterner R; Raushel FM
J Am Chem Soc; 2013 Aug; 135(31):11670-7. PubMed ID: 23837603
[TBL] [Abstract][Full Text] [Related]
9. Structure-based rational design of a phosphotriesterase.
Jackson CJ; Weir K; Herlt A; Khurana J; Sutherland TD; Horne I; Easton C; Russell RJ; Scott C; Oakeshott JG
Appl Environ Microbiol; 2009 Aug; 75(15):5153-6. PubMed ID: 19502439
[TBL] [Abstract][Full Text] [Related]
10. Expression and subcellular localization of organophosphate hydrolase in acephate-degrading Pseudomonas sp. strain Ind01 and its use as a potential biocatalyst for elimination of organophosphate insecticides.
Pinjari AB; Pandey JP; Kamireddy S; Siddavattam D
Lett Appl Microbiol; 2013 Jul; 57(1):63-8. PubMed ID: 23574004
[TBL] [Abstract][Full Text] [Related]
11. Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme.
Foo JL; Jackson CJ; Carr PD; Kim HK; Schenk G; Gahan LR; Ollis DL
Biochem J; 2010 Jul; 429(2):313-21. PubMed ID: 20459397
[TBL] [Abstract][Full Text] [Related]
12. Overcoming the Challenges of Enzyme Evolution To Adapt Phosphotriesterase for V-Agent Decontamination.
Bigley AN; Desormeaux E; Xiang DF; Bae SY; Harvey SP; Raushel FM
Biochemistry; 2019 Apr; 58(15):2039-2053. PubMed ID: 30893549
[TBL] [Abstract][Full Text] [Related]
13. Detoxification of organophosphate nerve agents by bacterial phosphotriesterase.
Ghanem E; Raushel FM
Toxicol Appl Pharmacol; 2005 Sep; 207(2 Suppl):459-70. PubMed ID: 15982683
[TBL] [Abstract][Full Text] [Related]
14. In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase.
Jackson CJ; Foo JL; Kim HK; Carr PD; Liu JW; Salem G; Ollis DL
J Mol Biol; 2008 Feb; 375(5):1189-96. PubMed ID: 18082180
[TBL] [Abstract][Full Text] [Related]
15. Phosphate-bound structure of an organophosphate-degrading enzyme from Agrobacterium radiobacter.
Ely F; Pedroso MM; Gahan LR; Ollis DL; Guddat LW; Schenk G
J Inorg Biochem; 2012 Jan; 106(1):19-22. PubMed ID: 22112835
[TBL] [Abstract][Full Text] [Related]
16. Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro.
Goldsmith M; Eckstein S; Ashani Y; Greisen P; Leader H; Sussman JL; Aggarwal N; Ovchinnikov S; Tawfik DS; Baker D; Thiermann H; Worek F
Arch Toxicol; 2016 Nov; 90(11):2711-2724. PubMed ID: 26612364
[TBL] [Abstract][Full Text] [Related]
17. Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp.
Luo XJ; Kong XD; Zhao J; Chen Q; Zhou J; Xu JH
Biotechnol Bioeng; 2014 Oct; 111(10):1920-30. PubMed ID: 24771278
[TBL] [Abstract][Full Text] [Related]
18. Increased expression of a bacterial phosphotriesterase in Escherichia coli through directed evolution.
McLoughlin SY; Jackson C; Liu JW; Ollis D
Protein Expr Purif; 2005 Jun; 41(2):433-40. PubMed ID: 15866732
[TBL] [Abstract][Full Text] [Related]
19. Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily.
Xiang DF; Kolb P; Fedorov AA; Meier MM; Fedorov LV; Nguyen TT; Sterner R; Almo SC; Shoichet BK; Raushel FM
Biochemistry; 2009 Mar; 48(10):2237-47. PubMed ID: 19159332
[TBL] [Abstract][Full Text] [Related]
20. Structural basis for natural lactonase and promiscuous phosphotriesterase activities.
Elias M; Dupuy J; Merone L; Mandrich L; Porzio E; Moniot S; Rochu D; Lecomte C; Rossi M; Masson P; Manco G; Chabriere E
J Mol Biol; 2008 Jun; 379(5):1017-28. PubMed ID: 18486146
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
