169 related articles for article (PubMed ID: 12679800)
1. A "combination oligonucleotide" antisense strategy to downregulate thymidylate synthase and decrease tumor cell growth and drug resistance.
Berg RW; Ferguson PJ; Vincent MD; Koropatnick DJ
Cancer Gene Ther; 2003 Apr; 10(4):278-86. PubMed ID: 12679800
[TBL] [Abstract][Full Text] [Related]
2. Tumor growth inhibition in vivo and G2/M cell cycle arrest induced by antisense oligodeoxynucleotide targeting thymidylate synthase.
Berg RW; Werner M; Ferguson PJ; Postenka C; Vincent M; Koropatnick DJ; Behrend E
J Pharmacol Exp Ther; 2001 Aug; 298(2):477-84. PubMed ID: 11454908
[TBL] [Abstract][Full Text] [Related]
3. Antisense down-regulation of thymidylate synthase to suppress growth and enhance cytotoxicity of 5-FUdR, 5-FU and Tomudex in HeLa cells.
Ferguson PJ; Collins O; Dean NM; DeMoor J; Li CS; Vincent MD; Koropatnick J
Br J Pharmacol; 1999 Aug; 127(8):1777-86. PubMed ID: 10482907
[TBL] [Abstract][Full Text] [Related]
4. The means to an end of tumor cell resistance to chemotherapeutic drugs targeting thymidylate synthase: shoot the messenger.
Berg RW; Ferguso PJ; DeMoor JM; Vincen MD; Koropatnick J
Curr Drug Targets; 2002 Aug; 3(4):297-309. PubMed ID: 12102601
[TBL] [Abstract][Full Text] [Related]
5. Antisense nucleic acids targeted to the thymidylate synthase (TS) mRNA translation start site stimulate TS gene transcription.
DeMoor JM; Vincent MD; Collins OM; Koropatnick J
Exp Cell Res; 1998 Aug; 243(1):11-21. PubMed ID: 9716444
[TBL] [Abstract][Full Text] [Related]
6. ODN 491, a novel antisense oligodeoxynucleotide that targets thymidylate synthase, exerts cell-specific effects in human tumor cell lines.
Jason TL; Figueredo R; Ferguson PJ; Vincent MD; Berg RW; Koropatnick J
DNA Cell Biol; 2008 May; 27(5):229-40. PubMed ID: 18358073
[TBL] [Abstract][Full Text] [Related]
7. Combination silencer RNA (siRNA) targeting Bcl-2 antagonizes siRNA against thymidylate synthase in human tumor cell lines.
Pandyra AA; Berg R; Vincent M; Koropatnick J
J Pharmacol Exp Ther; 2007 Jul; 322(1):123-32. PubMed ID: 17452420
[TBL] [Abstract][Full Text] [Related]
8. Antisense-induced down-regulation of thymidylate synthase and enhanced cytotoxicity of 5-FUdR in 5-FUdR-resistant HeLa cells.
Ferguson PJ; DeMoor JM; Vincent MD; Koropatnick J
Br J Pharmacol; 2001 Dec; 134(7):1437-46. PubMed ID: 11724749
[TBL] [Abstract][Full Text] [Related]
9. Combining small interfering RNAs targeting thymidylate synthase and thymidine kinase 1 or 2 sensitizes human tumor cells to 5-fluorodeoxyuridine and pemetrexed.
Di Cresce C; Figueredo R; Ferguson PJ; Vincent MD; Koropatnick J
J Pharmacol Exp Ther; 2011 Sep; 338(3):952-63. PubMed ID: 21673071
[TBL] [Abstract][Full Text] [Related]
10. Antisense targeting of thymidylate synthase (TS) mRNA increases TS gene transcription and TS protein: effects on human tumor cell sensitivity to TS enzyme-inhibiting drugs.
Jason TL; Berg RW; Vincent MD; Koropatnick J
Gene Expr; 2007; 13(4-5):227-39. PubMed ID: 17605297
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of thymidylate synthase activity by antisense oligodeoxynucleotide and possible role in thymineless treatment.
Lin SB; Ts'o PO; Sun SK; Choo KB; Yang FY; Lim YP; Tsai HL; Au LC
Mol Pharmacol; 2001 Sep; 60(3):474-9. PubMed ID: 11502877
[TBL] [Abstract][Full Text] [Related]
12. Desensitization and sensitization of cells to fluoropyrimidines with different antisenses directed against thymidylate synthase messenger RNA.
Ju J; Kane SE; Lenz HJ; Danenberg KD; Chu E; Danenberg PV
Clin Cancer Res; 1998 Sep; 4(9):2229-36. PubMed ID: 9748143
[TBL] [Abstract][Full Text] [Related]
13. The transfection of thymidylate synthase antisense suppresses oncogenic properties of a human colon cancer cell line and augments the antitumor effect of fluorouracil.
Matsuoka K; Tsukuda K; Suda M; Kobayashi K; Ota T; Okita A; Watanabe K; Suzuki E; Murakami M; Doihara H; Shimizu N
Int J Oncol; 2004 Jan; 24(1):217-22. PubMed ID: 14654960
[TBL] [Abstract][Full Text] [Related]
14. Thymidylate synthase inhibitors as anticancer agents: from bench to bedside.
Chu E; Callender MA; Farrell MP; Schmitz JC
Cancer Chemother Pharmacol; 2003 Jul; 52 Suppl 1():S80-9. PubMed ID: 12819937
[TBL] [Abstract][Full Text] [Related]
15. Combination studies of antifolates with 5-fluorouracil in colon cancer cell lines.
van der Wilt CL; Kuiper CM; Peters GJ
Oncol Res; 1999; 11(8):383-91. PubMed ID: 10803742
[TBL] [Abstract][Full Text] [Related]
16. Antisense ferritin oligonucleotides inhibit growth and induce apoptosis in human breast carcinoma cells.
Yang DC; Jiang X; Elliott RL; Head JF
Anticancer Res; 2002; 22(3):1513-24. PubMed ID: 12168831
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity.
Salatino M; Schillaci R; Proietti CJ; Carnevale R; Frahm I; Molinolo AA; Iribarren A; Charreau EH; Elizalde PV
Oncogene; 2004 Jul; 23(30):5161-74. PubMed ID: 15122317
[TBL] [Abstract][Full Text] [Related]
18. Comparison of thymidylate synthase (TS) protein up-regulation after exposure to TS inhibitors in normal and tumor cell lines and tissues.
Welsh SJ; Titley J; Brunton L; Valenti M; Monaghan P; Jackman AL; Aherne GW
Clin Cancer Res; 2000 Jun; 6(6):2538-46. PubMed ID: 10873110
[TBL] [Abstract][Full Text] [Related]
19. Correlations between thymidylate synthase expression and chemosensitivity to 5-fluorouracil, cell proliferation and clinical outcome in head and neck squamous cell carcinoma.
Yasumatsu R; Nakashima T; Uryu H; Ayada T; Wakasaki T; Kogo R; Masuda M; Fukushima M; Komune S
Chemotherapy; 2009; 55(1):36-41. PubMed ID: 19023200
[TBL] [Abstract][Full Text] [Related]
20. Stable inhibition of human thymidylate synthase expression following retroviral introduction of an siRNA gene.
Yang Z; Cloud A; Hughes D; Johnson LF
Cancer Gene Ther; 2006 Jan; 13(1):107-14. PubMed ID: 16052228
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
