These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 12679808)

  • 1. Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme.
    Bencharit S; Morton CL; Xue Y; Potter PM; Redinbo MR
    Nat Struct Biol; 2003 May; 10(5):349-56. PubMed ID: 12679808
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human carboxylesterase 1: from drug metabolism to drug discovery.
    Redinbo MR; Bencharit S; Potter PM
    Biochem Soc Trans; 2003 Jun; 31(Pt 3):620-4. PubMed ID: 12773168
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
    Fleming CD; Bencharit S; Edwards CC; Hyatt JL; Tsurkan L; Bai F; Fraga C; Morton CL; Howard-Williams EL; Potter PM; Redinbo MR
    J Mol Biol; 2005 Sep; 352(1):165-77. PubMed ID: 16081098
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin.
    Hatfield MJ; Tsurkan L; Hyatt JL; Yu X; Edwards CC; Hicks LD; Wadkins RM; Potter PM
    Br J Pharmacol; 2010 Aug; 160(8):1916-28. PubMed ID: 20649590
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1.
    Bencharit S; Edwards CC; Morton CL; Howard-Williams EL; Kuhn P; Potter PM; Redinbo MR
    J Mol Biol; 2006 Oct; 363(1):201-14. PubMed ID: 16962139
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human liver carboxylesterase hCE-1: binding specificity for cocaine, heroin, and their metabolites and analogs.
    Brzezinski MR; Spink BJ; Dean RA; Berkman CE; Cashman JR; Bosron WF
    Drug Metab Dispos; 1997 Sep; 25(9):1089-96. PubMed ID: 9311626
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of a bacterial cocaine esterase.
    Larsen NA; Turner JM; Stevens J; Rosser SJ; Basran A; Lerner RA; Bruce NC; Wilson IA
    Nat Struct Biol; 2002 Jan; 9(1):17-21. PubMed ID: 11742345
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protecting against cocaine, heroin, and sarin gas.
    McRee D
    Chem Biol; 2003 Apr; 10(4):295-7. PubMed ID: 12725856
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lessons from a bacterial cocaine esterase.
    Bosron WF; Hurley TD
    Nat Struct Biol; 2002 Jan; 9(1):4-5. PubMed ID: 11753424
    [No Abstract]   [Full Text] [Related]  

  • 10. Crystal structures of human carboxylesterase 1 in covalent complexes with the chemical warfare agents soman and tabun.
    Fleming CD; Edwards CC; Kirby SD; Maxwell DM; Potter PM; Cerasoli DM; Redinbo MR
    Biochemistry; 2007 May; 46(17):5063-71. PubMed ID: 17407327
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin.
    Pindel EV; Kedishvili NY; Abraham TL; Brzezinski MR; Zhang J; Dean RA; Bosron WF
    J Biol Chem; 1997 Jun; 272(23):14769-75. PubMed ID: 9169443
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isolation and pharmacological characterization of microsomal human liver flumazenil carboxylesterase.
    Kleingeist B; Böcker R; Geisslinger G; Brugger R
    J Pharm Pharm Sci; 1998; 1(1):38-46. PubMed ID: 10942971
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism of cocaine and heroin is catalyzed by the same human liver carboxylesterases.
    Kamendulis LM; Brzezinski MR; Pindel EV; Bosron WF; Dean RA
    J Pharmacol Exp Ther; 1996 Nov; 279(2):713-7. PubMed ID: 8930175
    [TBL] [Abstract][Full Text] [Related]  

  • 14. High-resolution crystal structure of plant carboxylesterase AeCXE1, from Actinidia eriantha, and its complex with a high-affinity inhibitor paraoxon.
    Ileperuma NR; Marshall SD; Squire CJ; Baker HM; Oakeshott JG; Russell RJ; Plummer KM; Newcomb RD; Baker EN
    Biochemistry; 2007 Feb; 46(7):1851-9. PubMed ID: 17256879
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition.
    Bencharit S; Morton CL; Hyatt JL; Kuhn P; Danks MK; Potter PM; Redinbo MR
    Chem Biol; 2003 Apr; 10(4):341-9. PubMed ID: 12725862
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin.
    Hemmert AC; Otto TC; Wierdl M; Edwards CC; Fleming CD; MacDonald M; Cashman JR; Potter PM; Cerasoli DM; Redinbo MR
    Mol Pharmacol; 2010 Apr; 77(4):508-16. PubMed ID: 20051531
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Development of Bacterial Carboxylesterase Biological Recognition Elements for Cocaine Detection.
    Mustafa SA
    Mol Biotechnol; 2018 Aug; 60(8):601-607. PubMed ID: 29951737
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nevadensin is a naturally occurring selective inhibitor of human carboxylesterase 1.
    Wang YQ; Weng ZM; Dou TY; Hou J; Wang DD; Ding LL; Zou LW; Yu Y; Chen J; Tang H; Ge GB
    Int J Biol Macromol; 2018 Dec; 120(Pt B):1944-1954. PubMed ID: 30268757
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The crystal structure of polyhydroxybutyrate depolymerase from Penicillium funiculosum provides insights into the recognition and degradation of biopolyesters.
    Hisano T; Kasuya K; Tezuka Y; Ishii N; Kobayashi T; Shiraki M; Oroudjev E; Hansma H; Iwata T; Doi Y; Saito T; Miki K
    J Mol Biol; 2006 Mar; 356(4):993-1004. PubMed ID: 16405909
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural plasticity and enzyme action: crystal structures of mycobacterium tuberculosis peptidyl-tRNA hydrolase.
    Selvaraj M; Roy S; Singh NS; Sangeetha R; Varshney U; Vijayan M
    J Mol Biol; 2007 Sep; 372(1):186-93. PubMed ID: 17619020
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.