BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 12682273)

  • 1. Human T cells express a functional ionotropic glutamate receptor GluR3, and glutamate by itself triggers integrin-mediated adhesion to laminin and fibronectin and chemotactic migration.
    Ganor Y; Besser M; Ben-Zakay N; Unger T; Levite M
    J Immunol; 2003 Apr; 170(8):4362-72. PubMed ID: 12682273
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TCR activation eliminates glutamate receptor GluR3 from the cell surface of normal human T cells, via an autocrine/paracrine granzyme B-mediated proteolytic cleavage.
    Ganor Y; Teichberg VI; Levite M
    J Immunol; 2007 Jan; 178(2):683-92. PubMed ID: 17202328
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of ionotropic glutamate receptor GLUR3 and effects of glutamate on MBP- and MOG-specific lymphocyte activation and chemotactic migration in multiple sclerosis patients.
    Sarchielli P; Di Filippo M; Candeliere A; Chiasserini D; Mattioni A; Tenaglia S; Bonucci M; Calabresi P
    J Neuroimmunol; 2007 Aug; 188(1-2):146-58. PubMed ID: 17628700
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human T-leukemia and T-lymphoma express glutamate receptor AMPA GluR3, and the neurotransmitter glutamate elevates the cancer-related matrix-metalloproteinases inducer CD147/EMMPRIN, MMP-9 secretion and engraftment of T-leukemia in vivo.
    Ganor Y; Grinberg I; Reis A; Cooper I; Goldstein RS; Levite M
    Leuk Lymphoma; 2009 Jun; 50(6):985-97. PubMed ID: 19391040
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glutamate, T cells and multiple sclerosis.
    Levite M
    J Neural Transm (Vienna); 2017 Jul; 124(7):775-798. PubMed ID: 28236206
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glutamate receptor antibodies in neurological diseases: anti-AMPA-GluR3 antibodies, anti-NMDA-NR1 antibodies, anti-NMDA-NR2A/B antibodies, anti-mGluR1 antibodies or anti-mGluR5 antibodies are present in subpopulations of patients with either: epilepsy, encephalitis, cerebellar ataxia, systemic lupus erythematosus (SLE) and neuropsychiatric SLE, Sjogren's syndrome, schizophrenia, mania or stroke. These autoimmune anti-glutamate receptor antibodies can bind neurons in few brain regions, activate glutamate receptors, decrease glutamate receptor's expression, impair glutamate-induced signaling and function, activate blood brain barrier endothelial cells, kill neurons, damage the brain, induce behavioral/psychiatric/cognitive abnormalities and ataxia in animal models, and can be removed or silenced in some patients by immunotherapy.
    Levite M
    J Neural Transm (Vienna); 2014 Aug; 121(8):1029-75. PubMed ID: 25081016
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells.
    Levite M; Zelig D; Friedman A; Ilouz N; Eilam R; Bromberg Z; Ramadhan Lasu AA; Arbel-Alon S; Edvardson S; Tarshish M; Riek LP; Lako RL; Reubinoff B; Lebendiker M; Yaish D; Stavsky A; Galun E
    J Autoimmun; 2020 Aug; 112():102462. PubMed ID: 32561150
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glutamate stimulates oligodendrocyte progenitor migration mediated via an alphav integrin/myelin proteolipid protein complex.
    Gudz TI; Komuro H; Macklin WB
    J Neurosci; 2006 Mar; 26(9):2458-66. PubMed ID: 16510724
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evidence that functional glutamate receptors are not expressed on rat or human cerebromicrovascular endothelial cells.
    Morley P; Small DL; Murray CL; Mealing GA; Poulter MO; Durkin JP; Stanimirovic DB
    J Cereb Blood Flow Metab; 1998 Apr; 18(4):396-406. PubMed ID: 9538905
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Properties of GluR3 receptors tagged with GFP at the amino or carboxyl terminus.
    Limon A; Reyes-Ruiz JM; Eusebi F; Miledi R
    Proc Natl Acad Sci U S A; 2007 Sep; 104(39):15526-30. PubMed ID: 17881566
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of ionotropic glutamate receptor GLUR3 and effects of glutamate on MBP- and MOG-specific lymphocyte activation and chemotactic migration in multiple sclerosis patients.
    Poulopoulou C; Hatzimanolis A
    J Neuroimmunol; 2008 Feb; 194(1-2):191; author reply 192. PubMed ID: 17996951
    [No Abstract]   [Full Text] [Related]  

  • 12. Dominant negative mutant of ionotropic glutamate receptor subunit GluR3: implications for the role of a cysteine residue for its channel activity and pharmacological properties.
    Watase K; Sekiguchi M; Matsui TA; Tagawa Y; Wada K
    Biochem J; 1997 Mar; 322 ( Pt 2)(Pt 2):385-91. PubMed ID: 9065754
    [TBL] [Abstract][Full Text] [Related]  

  • 13. AMPA receptor protein expression and function in astrocytes cultured from hippocampus.
    Fan D; Grooms SY; Araneda RC; Johnson AB; Dobrenis K; Kessler JA; Zukin RS
    J Neurosci Res; 1999 Aug; 57(4):557-71. PubMed ID: 10440906
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lead-Induced ERK Activation Is Mediated by GluR2 Non-containing AMPA Receptor in Cortical Neurons.
    Ishida K; Kotake Y; Sanoh S; Ohta S
    Biol Pharm Bull; 2017; 40(3):303-309. PubMed ID: 28250271
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glutamate mediates platelet activation through the AMPA receptor.
    Morrell CN; Sun H; Ikeda M; Beique JC; Swaim AM; Mason E; Martin TV; Thompson LE; Gozen O; Ampagoomian D; Sprengel R; Rothstein J; Faraday N; Huganir R; Lowenstein CJ
    J Exp Med; 2008 Mar; 205(3):575-84. PubMed ID: 18283118
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The neurotransmitter glutamate and human T cells: glutamate receptors and glutamate-induced direct and potent effects on normal human T cells, cancerous human leukemia and lymphoma T cells, and autoimmune human T cells.
    Ganor Y; Levite M
    J Neural Transm (Vienna); 2014 Aug; 121(8):983-1006. PubMed ID: 24584970
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacological characterization of the human ionotropic glutamate receptor subtype GluR3 stably expressed in mammalian cells.
    Varney MA; Rao SP; Jachec C; Deal C; Hess SD; Daggett LP; Lin F; Johnson EC; Veliçelebi G
    J Pharmacol Exp Ther; 1998 Apr; 285(1):358-70. PubMed ID: 9536032
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Complex pharmacological properties of recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subtypes.
    Stein E; Cox JA; Seeburg PH; Verdoorn TA
    Mol Pharmacol; 1992 Nov; 42(5):864-71. PubMed ID: 1279377
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stable expression of human homomeric and heteromeric AMPA receptor subunits in HEK293 cells.
    Nishimura S; Iizuka M; Wakamori M; Akiba I; Imoto K; Barsoumian EL
    Recept Channels; 2000; 7(2):139-50. PubMed ID: 10952090
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glutamate receptor-mediated effects on growth and morphology of human histiocytic lymphoma cells.
    Haas HS; Pfragner R; Siegl V; Ingolic E; Heintz E; Schauenstein K
    Int J Oncol; 2005 Sep; 27(3):867-74. PubMed ID: 16077940
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.