BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 12686103)

  • 21. Structure-based mechanism for early PLP-mediated steps of rabbit cytosolic serine hydroxymethyltransferase reaction.
    Di Salvo ML; Scarsdale JN; Kazanina G; Contestabile R; Schirch V; Wright HT
    Biomed Res Int; 2013; 2013():458571. PubMed ID: 23956983
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structural and functional insight into serine hydroxymethyltransferase from Helicobacter pylori.
    Sodolescu A; Dian C; Terradot L; Bouzhir-Sima L; Lestini R; Myllykallio H; Skouloubris S; Liebl U
    PLoS One; 2018; 13(12):e0208850. PubMed ID: 30550583
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Distinct biochemical properties of human serine hydroxymethyltransferase compared with the Plasmodium enzyme: implications for selective inhibition.
    Pinthong C; Maenpuen S; Amornwatcharapong W; Yuthavong Y; Leartsakulpanich U; Chaiyen P
    FEBS J; 2014 Jun; 281(11):2570-83. PubMed ID: 24698160
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Molecular organization, catalytic mechanism and function of serine hydroxymethyltransferase--a potential target for cancer chemotherapy.
    Rao NA; Talwar R; Savithri HS
    Int J Biochem Cell Biol; 2000 Apr; 32(4):405-16. PubMed ID: 10762066
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Chloroplastic Serine Hydroxymethyltransferase From
    Ruszkowski M; Sekula B; Ruszkowska A; Dauter Z
    Front Plant Sci; 2018; 9():584. PubMed ID: 29868052
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Lack of catalytic activity of a murine mRNA cytoplasmic serine hydroxymethyltransferase splice variant: evidence against alternative splicing as a regulatory mechanism.
    Liu X; Szebenyi DM; Anguera MC; Thiel DJ; Stover PJ
    Biochemistry; 2001 Apr; 40(16):4932-9. PubMed ID: 11305908
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Crystal structure of rabbit cytosolic serine hydroxymethyltransferase at 2.8 A resolution: mechanistic implications.
    Scarsdale JN; Kazanina G; Radaev S; Schirch V; Wright HT
    Biochemistry; 1999 Jun; 38(26):8347-58. PubMed ID: 10387080
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Conformational transitions driven by pyridoxal-5'-phosphate uptake in the psychrophilic serine hydroxymethyltransferase from Psychromonas ingrahamii.
    Angelaccio S; Dworkowski F; Di Bello A; Milano T; Capitani G; Pascarella S
    Proteins; 2014 Oct; 82(10):2831-41. PubMed ID: 25044250
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Purification and properties of serine hydroxymethyltransferase from Sulfolobus solfataricus.
    Delle Fratte S; White RH; Maras B; Bossa F; Schirch V
    J Bacteriol; 1997 Dec; 179(23):7456-61. PubMed ID: 9393711
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Kinetic mechanism and the rate-limiting step of Plasmodium vivax serine hydroxymethyltransferase.
    Maenpuen S; Amornwatcharapong W; Krasatong P; Sucharitakul J; Palfey BA; Yuthavong Y; Chitnumsub P; Leartsakulpanich U; Chaiyen P
    J Biol Chem; 2015 Mar; 290(13):8656-65. PubMed ID: 25678710
    [TBL] [Abstract][Full Text] [Related]  

  • 31. How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state.
    Giardina G; Brunotti P; Fiascarelli A; Cicalini A; Costa MG; Buckle AM; di Salvo ML; Giorgi A; Marani M; Paone A; Rinaldo S; Paiardini A; Contestabile R; Cutruzzolà F
    FEBS J; 2015 Apr; 282(7):1225-41. PubMed ID: 25619277
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control.
    Chitnumsub P; Jaruwat A; Riangrungroj P; Ittarat W; Noytanom K; Oonanant W; Vanichthanankul J; Chuankhayan P; Maenpuen S; Chen CJ; Chaiyen P; Yuthavong Y; Leartsakulpanich U
    Acta Crystallogr D Biol Crystallogr; 2014 Dec; 70(Pt 12):3177-86. PubMed ID: 25478836
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structural and functional studies of Bacillus stearothermophilus serine hydroxymethyltransferase: the role of Asn(341), Tyr(60) and Phe(351) in tetrahydrofolate binding.
    Pai VR; Rajaram V; Bisht S; Bhavani BS; Rao NA; Murthy MR; Savithri HS
    Biochem J; 2009 Mar; 418(3):635-42. PubMed ID: 19046138
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Function of the active-site lysine in Escherichia coli serine hydroxymethyltransferase.
    Schirch D; Delle Fratte S; Iurescia S; Angelaccio S; Contestabile R; Bossa F; Schirch V
    J Biol Chem; 1993 Nov; 268(31):23132-8. PubMed ID: 8226831
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Role of pro-297 in the catalytic mechanism of sheep liver serine hydroxymethyltransferase.
    Talwar R; Leelavathy V; Krishna Rao JV; Appaji Rao N; Savithri HS
    Biochem J; 2000 Sep; 350 Pt 3(Pt 3):849-53. PubMed ID: 10970801
    [TBL] [Abstract][Full Text] [Related]  

  • 36. In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed.
    Daidone F; Florio R; Rinaldo S; Contestabile R; di Salvo ML; Cutruzzolà F; Bossa F; Paiardini A
    Eur J Med Chem; 2011 May; 46(5):1616-21. PubMed ID: 21371789
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cloning and structural analysis of Mycobacterium leprae serine hydroxymethyltransferase.
    Sharma S; Bhakuni V
    Protein Expr Purif; 2007 Sep; 55(1):189-97. PubMed ID: 17540580
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Role of tyrosine 65 in the mechanism of serine hydroxymethyltransferase.
    Contestabile R; Angelaccio S; Bossa F; Wright HT; Scarsdale N; Kazanina G; Schirch V
    Biochemistry; 2000 Jun; 39(25):7492-500. PubMed ID: 10858298
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Free Energy Landscape and Proton Transfer Pathways of the Transimination Reaction at the Active site of the Serine Hydroxymethyltransferase Enzyme in Aqueous Medium.
    Soniya K; Chandra A
    J Phys Chem B; 2021 Nov; 125(43):11848-11856. PubMed ID: 34696588
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Reversible unfolding of sheep liver tetrameric serine hydroxymethyltransferase.
    Venkatesha B; Udgaonkar JB; Rao NA; Savithri HS
    Biochim Biophys Acta; 1998 Apr; 1384(1):141-52. PubMed ID: 9602099
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.