166 related articles for article (PubMed ID: 12688769)
1. Total synthesis of the microtubule stabilizing antitumor agent laulimalide and some nonnatural analogues: the power of Sharpless' asymmetric epoxidation.
Ahmed A; Hoegenauer EK; Enev VS; Hanbauer M; Kaehlig H; Ohler E; Mulzer J
J Org Chem; 2003 Apr; 68(8):3026-42. PubMed ID: 12688769
[TBL] [Abstract][Full Text] [Related]
2. The laulimalide family: total synthesis and biological evaluation of neolaulimalide, isolaulimalide, laulimalide and a nonnatural analogue.
Gollner A; Altmann KH; Gertsch J; Mulzer J
Chemistry; 2009 Jun; 15(24):5979-97. PubMed ID: 19402092
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of (-)-laulimalide analogues.
Wender PA; Hegde SG; Hubbard RD; Zhang L; Mooberry SL
Org Lett; 2003 Sep; 5(19):3507-9. PubMed ID: 12967311
[TBL] [Abstract][Full Text] [Related]
4. Total synthesis of microtubule-stabilizing agent (-)-laulimalide.
Ghosh AK; Wang Y; Kim JT
J Org Chem; 2001 Dec; 66(26):8973-82. PubMed ID: 11749630
[TBL] [Abstract][Full Text] [Related]
5. Total synthesis and biological evaluation of 11-desmethyllaulimalide, a highly potent simplified laulimalide analogue.
Wender PA; Hilinski MK; Soldermann N; Mooberry SL
Org Lett; 2006 Mar; 8(7):1507-10. PubMed ID: 16562928
[TBL] [Abstract][Full Text] [Related]
6. Microtubule-stabilizing marine metabolite laulimalide and its derivatives: synthetic approaches and antitumor activity.
Mulzer J; Ohler E
Chem Rev; 2003 Sep; 103(9):3753-86. PubMed ID: 12964883
[No Abstract] [Full Text] [Related]
7. Lessons learned from macrolide synthesis.
Mulzer J; Martin HJ
Chem Rec; 2004; 3(5):258-70. PubMed ID: 14762826
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: modification of the side chain.
Paterson I; Menche D; Håkansson AE; Longstaff A; Wong D; Barasoain I; Buey RM; Díaz JF
Bioorg Med Chem Lett; 2005 May; 15(9):2243-7. PubMed ID: 15837302
[TBL] [Abstract][Full Text] [Related]
9. In vitro and in vivo anticancer activities of synthetic (-)-laulimalide, a marine natural product microtubule stabilizing agent.
Liu J; Towle MJ; Cheng H; Saxton P; Reardon C; Wu J; Murphy EA; Kuznetsov G; Johannes CW; Tremblay MR; Zhao H; Pesant M; Fang FG; Vermeulen MW; Gallagher BM; Littlefield BA
Anticancer Res; 2007; 27(3B):1509-18. PubMed ID: 17595769
[TBL] [Abstract][Full Text] [Related]
10. Total synthesis and biological evaluation of potent analogues of dictyostatin: modification of the C2-C6 dienoate region.
Paterson I; Gardner NM; Guzmán E; Wright AE
Bioorg Med Chem Lett; 2008 Dec; 18(23):6268-72. PubMed ID: 18951787
[TBL] [Abstract][Full Text] [Related]
11. Laulimalide and isolaulimalide, new paclitaxel-like microtubule-stabilizing agents.
Mooberry SL; Tien G; Hernandez AH; Plubrukarn A; Davidson BS
Cancer Res; 1999 Feb; 59(3):653-60. PubMed ID: 9973214
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and biological properties of highly potent epothilone B analogues.
Nicolaou KC; Sasmal PK; Rassias G; Reddy MV; Altmann KH; Wartmann M; O'Brate A; Giannakakou P
Angew Chem Int Ed Engl; 2003 Aug; 42(30):3515-20. PubMed ID: 12900969
[No Abstract] [Full Text] [Related]
13. Synthesis of novel 11-desmethyl analogues of laulimalide by Nozaki-Kishi coupling.
Paterson I; Bergmann H; Menche D; Berkessel A
Org Lett; 2004 Apr; 6(8):1293-5. PubMed ID: 15070320
[TBL] [Abstract][Full Text] [Related]
14. Laulimalide and synthetic laulimalide analogues are synergistic with paclitaxel and 2-methoxyestradiol.
Clark EA; Hills PM; Davidson BS; Wender PA; Mooberry SL
Mol Pharm; 2006; 3(4):457-67. PubMed ID: 16889440
[TBL] [Abstract][Full Text] [Related]
15. Design and total synthesis of a superior family of epothilone analogues, which eliminate xenograft tumors to a nonrelapsable state.
Chou TC; Dong H; Rivkin A; Yoshimura F; Gabarda AE; Cho YS; Tong WP; Danishefsky SJ
Angew Chem Int Ed Engl; 2003 Oct; 42(39):4762-7. PubMed ID: 14562342
[No Abstract] [Full Text] [Related]
16. Total synthesis of the microtubule-stabilizing agent (-)-laulimalide.
Paterson I; De Savi C; Tudge M
Org Lett; 2001 Oct; 3(20):3149-52. PubMed ID: 11574017
[TBL] [Abstract][Full Text] [Related]
17. Epothilones as lead structures for the synthesis-based discovery of new chemotypes for microtubule stabilization.
Feyen F; Cachoux F; Gertsch J; Wartmann M; Altmann KH
Acc Chem Res; 2008 Jan; 41(1):21-31. PubMed ID: 18159935
[TBL] [Abstract][Full Text] [Related]
18. Laulimalide and paclitaxel: a comparison of their effects on tubulin assembly and their synergistic action when present simultaneously.
Gapud EJ; Bai R; Ghosh AK; Hamel E
Mol Pharmacol; 2004 Jul; 66(1):113-21. PubMed ID: 15213302
[TBL] [Abstract][Full Text] [Related]
19. Application of ring-closing metathesis reactions in the synthesis of epothilones.
Rivkin A; Cho YS; Gabarda AE; Yoshimura F; Danishefsky SJ
J Nat Prod; 2004 Feb; 67(2):139-43. PubMed ID: 14987048
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of 10,11-dihydrodictyostatin, a potent analogue of the marine anticancer agent dictyostatin.
Paterson I; Gardner NM; Poullennec KG; Wright AE
J Nat Prod; 2008 Mar; 71(3):364-9. PubMed ID: 18081257
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]