These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 12690102)

  • 21. Functional characterization and structural modeling of obesity associated mutations in the melanocortin 4 receptor.
    Tan K; Pogozheva ID; Yeo GS; Hadaschik D; Keogh JM; Haskell-Leuvano C; O'Rahilly S; Mosberg HI; Farooqi IS
    Endocrinology; 2009 Jan; 150(1):114-25. PubMed ID: 18801902
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Substituted NDP-MSH peptides paired with mutant melanocortin-4 receptors demonstrate the role of transmembrane 6 in receptor activation.
    Fleck BA; Ling N; Chen C
    Biochemistry; 2007 Sep; 46(37):10473-83. PubMed ID: 17713970
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
    Frändberg PA; Doufexis M; Kapas S; Chhajlani V
    Biochem Biophys Res Commun; 2001 Mar; 281(4):851-7. PubMed ID: 11237737
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat.
    Adan RA; Szklarczyk AW; Oosterom J; Brakkee JH; Nijenhuis WA; Schaaper WM; Meloen RH; Gispen WH
    Eur J Pharmacol; 1999 Aug; 378(3):249-58. PubMed ID: 10493100
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Characterisation of the melanocortin 4 receptor by radioligand binding.
    Schiöth HB; Muceniece R; Wikberg JE
    Pharmacol Toxicol; 1996 Sep; 79(3):161-5. PubMed ID: 8884876
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Differential Signaling Profiles of MC4R Mutations with Three Different Ligands.
    Paisdzior S; Dimitriou IM; Schöpe PC; Annibale P; Scheerer P; Krude H; Lohse MJ; Biebermann H; Kühnen P
    Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32059383
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Functional characterization of mutations in melanocortin-4 receptor associated with human obesity.
    Ho G; MacKenzie RG
    J Biol Chem; 1999 Dec; 274(50):35816-22. PubMed ID: 10585465
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Heterogeneity of brain melanocortin receptors suggested by differential ligand binding in situ.
    Tatro JB; Entwistle ML
    Brain Res; 1994 Jan; 635(1-2):148-58. PubMed ID: 8173950
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Putative targets of CNS melanocortin receptor activity.
    Lamar CR; Gardner W; Brazda A; Kesterson RA
    Ann N Y Acad Sci; 2003 Jun; 994():211-7. PubMed ID: 12851318
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Point mutations in the melanocortin-4 receptor cause variable obesity in mice.
    Meehan TP; Tabeta K; Du X; Woodward LS; Firozi K; Beutler B; Justice MJ
    Mamm Genome; 2006 Dec; 17(12):1162-71. PubMed ID: 17143585
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Melanocortin-4 receptor mutations in obesity.
    Santini F; Maffei M; Pelosini C; Salvetti G; Scartabelli G; Pinchera A
    Adv Clin Chem; 2009; 48():95-109. PubMed ID: 19803416
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Melanocortin 4 receptor distribution in the human hypothalamus.
    Siljee JE; Unmehopa UA; Kalsbeek A; Swaab DF; Fliers E; Alkemade A
    Eur J Endocrinol; 2013 Mar; 168(3):361-9. PubMed ID: 23211571
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Characterisation of D117A and H260A mutations in the melanocortin 1 receptor.
    Schiöth HB; Muceniece R; Szardenings M; Prusis P; Lindeberg G; Sharma SD; Hruby VJ; Wikberg JE
    Mol Cell Endocrinol; 1997 Feb; 126(2):213-9. PubMed ID: 9089659
    [TBL] [Abstract][Full Text] [Related]  

  • 34. A frameshift mutation in MC4R associated with dominantly inherited human obesity.
    Yeo GS; Farooqi IS; Aminian S; Halsall DJ; Stanhope RG; O'Rahilly S
    Nat Genet; 1998 Oct; 20(2):111-2. PubMed ID: 9771698
    [No Abstract]   [Full Text] [Related]  

  • 35. Inverse agonism gains weight.
    Adan RA; Kas MJ
    Trends Pharmacol Sci; 2003 Jun; 24(6):315-21. PubMed ID: 12823958
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Pharmacological chaperones restore function to MC4R mutants responsible for severe early-onset obesity.
    René P; Le Gouill C; Pogozheva ID; Lee G; Mosberg HI; Farooqi IS; Valenzano KJ; Bouvier M
    J Pharmacol Exp Ther; 2010 Dec; 335(3):520-32. PubMed ID: 20826565
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Identification of domains directing specificity of coupling to G-proteins for the melanocortin MC3 and MC4 receptors.
    Kim CS; Lee SH; Kim RY; Kim BJ; Li SZ; Lee IH; Lee EJ; Lim SK; Bae YS; Lee W; Baik JH
    J Biol Chem; 2002 Aug; 277(35):31310-7. PubMed ID: 12045190
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Agouti-related protein has an inhibitory paracrine role in the rat adrenal gland.
    Dhillo WS; Small CJ; Gardiner JV; Bewick GA; Whitworth EJ; Jethwa PH; Seal LJ; Ghatei MA; Hinson JP; Bloom SR
    Biochem Biophys Res Commun; 2003 Jan; 301(1):102-7. PubMed ID: 12535647
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist.
    Xiang Z; Litherland SA; Sorensen NB; Proneth B; Wood MS; Shaw AM; Millard WJ; Haskell-Luevano C
    Biochemistry; 2006 Jun; 45(23):7277-88. PubMed ID: 16752916
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans.
    Srinivasan S; Lubrano-Berthelier C; Govaerts C; Picard F; Santiago P; Conklin BR; Vaisse C
    J Clin Invest; 2004 Oct; 114(8):1158-64. PubMed ID: 15489963
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.