153 related articles for article (PubMed ID: 12697672)
1. Hepatocyte nuclear factor 4 alpha isoforms originated from the P1 promoter are expressed in human pancreatic beta-cells and exhibit stronger transcriptional potentials than P2 promoter-driven isoforms.
Eeckhoute J; Moerman E; Bouckenooghe T; Lukoviak B; Pattou F; Formstecher P; Kerr-Conte J; Vandewalle B; Laine B
Endocrinology; 2003 May; 144(5):1686-94. PubMed ID: 12697672
[TBL] [Abstract][Full Text] [Related]
2. Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function.
Hansen SK; Párrizas M; Jensen ML; Pruhova S; Ek J; Boj SF; Johansen A; Maestro MA; Rivera F; Eiberg H; Andel M; Lebl J; Pedersen O; Ferrer J; Hansen T
J Clin Invest; 2002 Sep; 110(6):827-33. PubMed ID: 12235114
[TBL] [Abstract][Full Text] [Related]
3. Synergistic activation of the Atlantic salmon hepatocyte nuclear factor (HNF) 1 promoter by the orphan nuclear receptors HNF4 and chicken ovalbumin upstream promoter transcription factor I (COUP-TFI).
McNair A; Cereghini S; Brand H; Smith T; Breillat C; Gannon F
Biochem J; 2000 Dec; 352 Pt 2(Pt 2):557-64. PubMed ID: 11085951
[TBL] [Abstract][Full Text] [Related]
4. Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression.
Jung D; Kullak-Ublick GA
Hepatology; 2003 Mar; 37(3):622-31. PubMed ID: 12601360
[TBL] [Abstract][Full Text] [Related]
5. Mutations in hepatocyte nuclear factor 4alpha (HNF4alpha) gene associated with diabetes result in greater loss of HNF4alpha function in pancreatic beta-cells than in nonpancreatic beta-cells and in reduced activation of the apolipoprotein CIII promoter in hepatic cells.
Oxombre B; Moerman E; Eeckhoute J; Formstecher P; Laine B
J Mol Med (Berl); 2002 Jul; 80(7):423-30. PubMed ID: 12110948
[TBL] [Abstract][Full Text] [Related]
6. The activity of the activation function 2 of the human hepatocyte nuclear factor 4 (HNF-4alpha) is differently modulated by F domains from various origins.
Suaud L; Formstecher P; Laine B
Biochem J; 1999 May; 340 ( Pt 1)(Pt 1):161-9. PubMed ID: 10229671
[TBL] [Abstract][Full Text] [Related]
7. A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young.
Thomas H; Jaschkowitz K; Bulman M; Frayling TM; Mitchell SM; Roosen S; Lingott-Frieg A; Tack CJ; Ellard S; Ryffel GU; Hattersley AT
Hum Mol Genet; 2001 Sep; 10(19):2089-97. PubMed ID: 11590126
[TBL] [Abstract][Full Text] [Related]
8. Activation of the insulin gene promoter through a direct effect of hepatocyte nuclear factor 4 alpha.
Bartoov-Shifman R; Hertz R; Wang H; Wollheim CB; Bar-Tana J; Walker MD
J Biol Chem; 2002 Jul; 277(29):25914-9. PubMed ID: 11994285
[TBL] [Abstract][Full Text] [Related]
9. Molecular biology. HNFs--linking the liver and pancreatic islets in diabetes.
Kulkarni RN; Kahn CR
Science; 2004 Feb; 303(5662):1311-2. PubMed ID: 14988544
[No Abstract] [Full Text] [Related]
10. Maturity-onset diabetes of the young Type 1 (MODY1)-associated mutations R154X and E276Q in hepatocyte nuclear factor 4alpha (HNF4alpha) gene impair recruitment of p300, a key transcriptional co-activator.
Eeckhoute J; Formstecher P; Laine B
Mol Endocrinol; 2001 Jul; 15(7):1200-10. PubMed ID: 11435618
[TBL] [Abstract][Full Text] [Related]
11. Differential promoter usage in prolactin receptor gene expression: hepatocyte nuclear factor 4 binds to and activates the promoter preferentially active in the liver.
Møldrup A; Ormandy C; Nagano M; Murthy K; Banville D; Tronche F; Kelly PA
Mol Endocrinol; 1996 Jun; 10(6):661-71. PubMed ID: 8776726
[TBL] [Abstract][Full Text] [Related]
12. Regulation of hepatitis B virus core promoter by transcription factors HNF1 and HNF4 and the viral X protein.
Zheng Y; Li J; Ou JH
J Virol; 2004 Jul; 78(13):6908-14. PubMed ID: 15194767
[TBL] [Abstract][Full Text] [Related]
13. Retinoic acid mediates down-regulation of the alpha-fetoprotein gene through decreased expression of hepatocyte nuclear factors.
Magee TR; Cai Y; El-Houseini ME; Locker J; Wan YJ
J Biol Chem; 1998 Nov; 273(45):30024-32. PubMed ID: 9792724
[TBL] [Abstract][Full Text] [Related]
14. Hepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets.
Párrizas M; Maestro MA; Boj SF; Paniagua A; Casamitjana R; Gomis R; Rivera F; Ferrer J
Mol Cell Biol; 2001 May; 21(9):3234-43. PubMed ID: 11287626
[TBL] [Abstract][Full Text] [Related]
15. Rare variants identified in the HNF- 4 alpha beta-cell-specific promoter and alternative exon 1 lack biological significance in maturity onset diabetes of the young and young onset Type II diabetes.
Mitchell SM; Vaxillaire M; Thomas H; Parrizas M; Benmezroua Y; Costa A; Hansen T; Owen KR; Tuomi T; Pirie F; Ryffel GU; Ferrer J; Froguel P; Hattersley AT; Frayling TM
Diabetologia; 2002 Sep; 45(9):1344-8. PubMed ID: 12242469
[TBL] [Abstract][Full Text] [Related]
16. Developmental and tissue-specific regulation of hepatocyte nuclear factor 4-alpha (HNF4-alpha) isoforms in rodents.
Dean S; Tang JI; Seckl JR; Nyirenda MJ
Gene Expr; 2010; 14(6):337-44. PubMed ID: 20635575
[TBL] [Abstract][Full Text] [Related]
17. A transcription factor regulatory circuit in differentiated pancreatic cells.
Boj SF; Parrizas M; Maestro MA; Ferrer J
Proc Natl Acad Sci U S A; 2001 Dec; 98(25):14481-6. PubMed ID: 11717395
[TBL] [Abstract][Full Text] [Related]
18. Characterization of the human PPARalpha promoter: identification of a functional nuclear receptor response element.
Pineda Torra I; Jamshidi Y; Flavell DM; Fruchart JC; Staels B
Mol Endocrinol; 2002 May; 16(5):1013-28. PubMed ID: 11981036
[TBL] [Abstract][Full Text] [Related]
19. Involvement of STAT5 (signal transducer and activator of transcription 5) and HNF-4 (hepatocyte nuclear factor 4) in the transcriptional control of the hnf6 gene by growth hormone.
Lahuna O; Rastegar M; Maiter D; Thissen JP; Lemaigre FP; Rousseau GG
Mol Endocrinol; 2000 Feb; 14(2):285-94. PubMed ID: 10674400
[TBL] [Abstract][Full Text] [Related]
20. A transcriptional hierarchy involved in mammalian cell-type specification.
Kuo CJ; Conley PB; Chen L; Sladek FM; Darnell JE; Crabtree GR
Nature; 1992 Jan; 355(6359):457-61. PubMed ID: 1734282
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]