BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 12697749)

  • 1. AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance.
    Yuan ZQ; Feldman RI; Sussman GE; Coppola D; Nicosia SV; Cheng JQ
    J Biol Chem; 2003 Jun; 278(26):23432-40. PubMed ID: 12697749
    [TBL] [Abstract][Full Text] [Related]  

  • 2. c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade.
    Desbiens KM; Deschesnes RG; Labrie MM; Desfossés Y; Lambert H; Landry J; Bellmann K
    Biochem J; 2003 Jun; 372(Pt 2):631-41. PubMed ID: 12646044
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells.
    Mansouri A; Ridgway LD; Korapati AL; Zhang Q; Tian L; Wang Y; Siddik ZH; Mills GB; Claret FX
    J Biol Chem; 2003 May; 278(21):19245-56. PubMed ID: 12637505
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death.
    Sarker KP; Biswas KK; Yamakuchi M; Lee KY; Hahiguchi T; Kracht M; Kitajima I; Maruyama I
    J Neurochem; 2003 Apr; 85(1):50-61. PubMed ID: 12641726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells.
    Yuan ZQ; Feldman RI; Sun M; Olashaw NE; Coppola D; Sussman GE; Shelley SA; Nicosia SV; Cheng JQ
    J Biol Chem; 2002 Aug; 277(33):29973-82. PubMed ID: 12048203
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Defective stress kinase and Bak activation in response to ionizing radiation but not cisplatin in a non-small cell lung carcinoma cell line.
    Viktorsson K; Ekedahl J; Lindebro MC; Lewensohn R; Zhivotovsky B; Linder S; Shoshan MC
    Exp Cell Res; 2003 Oct; 289(2):256-64. PubMed ID: 14499626
    [TBL] [Abstract][Full Text] [Related]  

  • 7. alpha-TEA inhibits survival and enhances death pathways in cisplatin sensitive and resistant human ovarian cancer cells.
    Yu W; Shun MC; Anderson K; Chen H; Sanders BG; Kline K
    Apoptosis; 2006 Oct; 11(10):1813-23. PubMed ID: 16850165
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selenite suppresses hydrogen peroxide-induced cell apoptosis through inhibition of ASK1/JNK and activation of PI3-K/Akt pathways.
    Yoon SO; Kim MM; Park SJ; Kim D; Chung J; Chung AS
    FASEB J; 2002 Jan; 16(1):111-3. PubMed ID: 11709494
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.
    Nakagawa H; Hirata Y; Takeda K; Hayakawa Y; Sato T; Kinoshita H; Sakamoto K; Nakata W; Hikiba Y; Omata M; Yoshida H; Koike K; Ichijo H; Maeda S
    Hepatology; 2011 Jul; 54(1):185-95. PubMed ID: 21488081
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons.
    Yamagishi S; Yamada M; Koshimizu H; Takai S; Hatanaka H; Takeda K; Ichijo H; Shimoke K; Ikeuchi T
    J Biochem; 2003 Jun; 133(6):719-24. PubMed ID: 12869527
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis.
    Saeki K; Kobayashi N; Inazawa Y; Zhang H; Nishitoh H; Ichijo H; Saeki K; Isemura M; Yuo A
    Biochem J; 2002 Dec; 368(Pt 3):705-20. PubMed ID: 12206715
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin.
    Hayakawa J; Ohmichi M; Kurachi H; Kanda Y; Hisamoto K; Nishio Y; Adachi K; Tasaka K; Kanzaki T; Murata Y
    Cancer Res; 2000 Nov; 60(21):5988-94. PubMed ID: 11085518
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation.
    Li X; Zhang R; Luo D; Park SJ; Wang Q; Kim Y; Min W
    J Biol Chem; 2005 Apr; 280(15):15061-70. PubMed ID: 15701637
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1.
    Kim AH; Khursigara G; Sun X; Franke TF; Chao MV
    Mol Cell Biol; 2001 Feb; 21(3):893-901. PubMed ID: 11154276
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular Mechanisms of IRE1α-ASK1 Pathway Reactions to Unfolded Protein Response in DRN Neurons of Post-Traumatic Stress Disorder Rats.
    Kong F; Han F; Xu Y; Shi Y
    J Mol Neurosci; 2017 Apr; 61(4):531-541. PubMed ID: 28210980
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Daxx deletion mutant (amino acids 501-625)-induced apoptosis occurs through the JNK/p38-Bax-dependent mitochondrial pathway.
    Song JJ; Lee YJ
    J Cell Biochem; 2004 Aug; 92(6):1257-70. PubMed ID: 15258908
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation.
    Zhang H; Zhang H; Lin Y; Li J; Pober JS; Min W
    J Biol Chem; 2007 May; 282(20):14788-96. PubMed ID: 17389591
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways.
    Choi JA; Park MT; Kang CM; Um HD; Bae S; Lee KH; Kim TH; Kim JH; Cho CK; Lee YS; Chung HY; Lee SJ
    Oncogene; 2004 Jan; 23(1):9-20. PubMed ID: 14712206
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ebselen inhibits NO-induced apoptosis of differentiated PC12 cells via inhibition of ASK1-p38 MAPK-p53 and JNK signaling and activation of p44/42 MAPK and Bcl-2.
    Sarker KP; Biswas KK; Rosales JL; Yamaji K; Hashiguchi T; Lee KY; Maruyama I
    J Neurochem; 2003 Dec; 87(6):1345-53. PubMed ID: 14713291
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [The role of mitogen-activated protein kinase cascades in inhibition of proliferation in human prostate carcinoma cells by raloxifene: an in vitro experiment].
    Zhang YX; Kong CZ
    Zhonghua Yi Xue Za Zhi; 2008 Jan; 88(4):271-5. PubMed ID: 18361842
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.