These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 12699716)

  • 1. Dysregulatory dysequilibrium of gene transcription and of nuclear transport in polyglutamine neuro-degeneration.
    Agius LM
    Med Hypotheses; 2003 Jun; 60(6):869-73. PubMed ID: 12699716
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.
    Chen HK; Fernandez-Funez P; Acevedo SF; Lam YC; Kaytor MD; Fernandez MH; Aitken A; Skoulakis EM; Orr HT; Botas J; Zoghbi HY
    Cell; 2003 May; 113(4):457-68. PubMed ID: 12757707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice.
    Yvert G; Lindenberg KS; Picaud S; Landwehrmeyer GB; Sahel JA; Mandel JL
    Hum Mol Genet; 2000 Oct; 9(17):2491-506. PubMed ID: 11030754
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7.
    La Spada AR; Fu YH; Sopher BL; Libby RT; Wang X; Li LY; Einum DD; Huang J; Possin DE; Smith AC; Martinez RA; Koszdin KL; Treuting PM; Ware CB; Hurley JB; Ptácek LJ; Chen S
    Neuron; 2001 Sep; 31(6):913-27. PubMed ID: 11580893
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SCA7 mouse models show selective stabilization of mutant ataxin-7 and similar cellular responses in different neuronal cell types.
    Yvert G; Lindenberg KS; Devys D; Helmlinger D; Landwehrmeyer GB; Mandel JL
    Hum Mol Genet; 2001 Aug; 10(16):1679-92. PubMed ID: 11487572
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice.
    Emamian ES; Kaytor MD; Duvick LA; Zu T; Tousey SK; Zoghbi HY; Clark HB; Orr HT
    Neuron; 2003 May; 38(3):375-87. PubMed ID: 12741986
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Non-expanded polyglutamine proteins in intranuclear inclusions of hereditary ataxias--triple-labeling immunofluorescence study.
    Uchihara T; Fujigasaki H; Koyano S; Nakamura A; Yagishita S; Iwabuchi K
    Acta Neuropathol; 2001 Aug; 102(2):149-52. PubMed ID: 11563629
    [TBL] [Abstract][Full Text] [Related]  

  • 8. H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse.
    Wang HL; Hu SH; Chou AH; Wang SS; Weng YH; Yeh TH
    Neuropharmacology; 2013 Jul; 70():1-11. PubMed ID: 23347954
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization.
    Chen S; Peng GH; Wang X; Smith AC; Grote SK; Sopher BL; La Spada AR
    Hum Mol Genet; 2004 Jan; 13(1):53-67. PubMed ID: 14613968
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract.
    Yue S; Serra HG; Zoghbi HY; Orr HT
    Hum Mol Genet; 2001 Jan; 10(1):25-30. PubMed ID: 11136710
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional malfunctioning of heat shock protein gene expression in spinocerebellar ataxias.
    Huen NY; Wong SL; Chan HY
    Cerebellum; 2007; 6(2):111-7. PubMed ID: 17510910
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Promyelocytic leukemia protein is redistributed during the formation of intranuclear inclusions independent of polyglutamine expansion: an immunohistochemical study on Marinesco bodies.
    Kumada S; Uchihara T; Hayashi M; Nakamura A; Kikuchi E; Mizutani T; Oda M
    J Neuropathol Exp Neurol; 2002 Nov; 61(11):984-91. PubMed ID: 12430715
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amino acid sequences flanking polyglutamine stretches influence their potential for aggregate formation.
    Nozaki K; Onodera O; Takano H; Tsuji S
    Neuroreport; 2001 Oct; 12(15):3357-64. PubMed ID: 11711886
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Polyglutamine-induced neurodegeneration in SCA3 is not mitigated by non-expanded ataxin-3: conclusions from double-transgenic mouse models.
    Hübener J; Riess O
    Neurobiol Dis; 2010 Apr; 38(1):116-24. PubMed ID: 20079840
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Spinocerebellar ataxia 7 (SCA7).
    Lebre AS; Brice A
    Cytogenet Genome Res; 2003; 100(1-4):154-63. PubMed ID: 14526176
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Polyglutamine-expanded ataxin-7 upregulates Bax expression by activating p53 in cerebellar and inferior olivary neurons.
    Wang HL; Chou AH; Lin AC; Chen SY; Weng YH; Yeh TH
    Exp Neurol; 2010 Aug; 224(2):486-94. PubMed ID: 20546728
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration.
    Palhan VB; Chen S; Peng GH; Tjernberg A; Gamper AM; Fan Y; Chait BT; La Spada AR; Roeder RG
    Proc Natl Acad Sci U S A; 2005 Jun; 102(24):8472-7. PubMed ID: 15932940
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CREB-binding protein sequestration by expanded polyglutamine.
    McCampbell A; Taylor JP; Taye AA; Robitschek J; Li M; Walcott J; Merry D; Chai Y; Paulson H; Sobue G; Fischbeck KH
    Hum Mol Genet; 2000 Sep; 9(14):2197-202. PubMed ID: 10958659
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Qs in the nucleus.
    Orr HT
    Neuron; 2001 Sep; 31(6):875-6. PubMed ID: 11580886
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.
    Lee WC; Yoshihara M; Littleton JT
    Proc Natl Acad Sci U S A; 2004 Mar; 101(9):3224-9. PubMed ID: 14978262
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.