1616 related articles for article (PubMed ID: 12702569)
21. Flavopiridol down-regulates antiapoptotic proteins and sensitizes human breast cancer cells to epothilone B-induced apoptosis.
Wittmann S; Bali P; Donapaty S; Nimmanapalli R; Guo F; Yamaguchi H; Huang M; Jove R; Wang HG; Bhalla K
Cancer Res; 2003 Jan; 63(1):93-9. PubMed ID: 12517783
[TBL] [Abstract][Full Text] [Related]
22. Synergistic antileukemic interactions between 17-AAG and UCN-01 involve interruption of RAF/MEK- and AKT-related pathways.
Jia W; Yu C; Rahmani M; Krystal G; Sausville EA; Dent P; Grant S
Blood; 2003 Sep; 102(5):1824-32. PubMed ID: 12738674
[TBL] [Abstract][Full Text] [Related]
23. Selective protection of mitogenically stimulated human lymphocytes but not leukemic cells from cytosine arabinoside-induced apoptosis by LY294002, a phosphoinositol-3 kinase inhibitor.
Du L; Smolewski P; Bedner E; Traganos F; Darzynkiewicz Z
Int J Oncol; 2001 Oct; 19(4):811-9. PubMed ID: 11562760
[TBL] [Abstract][Full Text] [Related]
24. Potentiation of the lethality of the histone deacetylase inhibitor LAQ824 by the cyclin-dependent kinase inhibitor roscovitine in human leukemia cells.
Rosato RR; Almenara JA; Maggio SC; Atadja P; Craig R; Vrana J; Dent P; Grant S
Mol Cancer Ther; 2005 Nov; 4(11):1772-85. PubMed ID: 16275999
[TBL] [Abstract][Full Text] [Related]
25. Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.
Uddin S; Hussain AR; Al-Hussein KA; Manogaran PS; Wickrema A; Gutierrez MI; Bhatia KG
Clin Cancer Res; 2005 Apr; 11(8):3102-8. PubMed ID: 15837766
[TBL] [Abstract][Full Text] [Related]
26. Contribution of disruption of the nuclear factor-kappaB pathway to induction of apoptosis in human leukemia cells by histone deacetylase inhibitors and flavopiridol.
Gao N; Dai Y; Rahmani M; Dent P; Grant S
Mol Pharmacol; 2004 Oct; 66(4):956-63. PubMed ID: 15235103
[TBL] [Abstract][Full Text] [Related]
27. Histone deacetylase inhibitors promote STI571-mediated apoptosis in STI571-sensitive and -resistant Bcr/Abl+ human myeloid leukemia cells.
Yu C; Rahmani M; Almenara J; Subler M; Krystal G; Conrad D; Varticovski L; Dent P; Grant S
Cancer Res; 2003 May; 63(9):2118-26. PubMed ID: 12727828
[TBL] [Abstract][Full Text] [Related]
28. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
Gao N; Flynn DC; Zhang Z; Zhong XS; Walker V; Liu KJ; Shi X; Jiang BH
Am J Physiol Cell Physiol; 2004 Aug; 287(2):C281-91. PubMed ID: 15028555
[TBL] [Abstract][Full Text] [Related]
29. Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells.
Tabellini G; Cappellini A; Tazzari PL; Falà F; Billi AM; Manzoli L; Cocco L; Martelli AM
J Cell Physiol; 2005 Feb; 202(2):623-34. PubMed ID: 15316930
[TBL] [Abstract][Full Text] [Related]
30. Protein kinase C-dependent activation of the tumor necrosis factor receptor-mediated extrinsic cell death pathway underlies enhanced apoptosis in human myeloid leukemia cells exposed to bryostatin 1 and flavopiridol.
Cartee L; Maggio SC; Smith R; Sankala HM; Dent P; Grant S
Mol Cancer Ther; 2003 Jan; 2(1):83-93. PubMed ID: 12533676
[TBL] [Abstract][Full Text] [Related]
31. 2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process.
Gao N; Rahmani M; Dent P; Grant S
Oncogene; 2005 May; 24(23):3797-809. PubMed ID: 15782127
[TBL] [Abstract][Full Text] [Related]
32. Flavopiridol potentiates STI571-induced mitochondrial damage and apoptosis in BCR-ABL-positive human leukemia cells.
Yu C; Krystal G; Dent P; Grant S
Clin Cancer Res; 2002 Sep; 8(9):2976-84. PubMed ID: 12231544
[TBL] [Abstract][Full Text] [Related]
33. Growth factor-stimulated phosphorylation of Akt and p70(S6K) is differentially inhibited by LY294002 and Wortmannin.
Adi S; Wu NY; Rosenthal SM
Endocrinology; 2001 Jan; 142(1):498-501. PubMed ID: 11145615
[TBL] [Abstract][Full Text] [Related]
34. Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.
MacKeigan JP; Taxman DJ; Hunter D; Earp HS; Graves LM; Ting JP
Clin Cancer Res; 2002 Jul; 8(7):2091-9. PubMed ID: 12114408
[TBL] [Abstract][Full Text] [Related]
35. LY294002 and LY303511 sensitize tumor cells to drug-induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3-kinase-Akt pathway.
Poh TW; Pervaiz S
Cancer Res; 2005 Jul; 65(14):6264-74. PubMed ID: 16024628
[TBL] [Abstract][Full Text] [Related]
36. Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.
Pene F; Claessens YE; Muller O; Viguié F; Mayeux P; Dreyfus F; Lacombe C; Bouscary D
Oncogene; 2002 Sep; 21(43):6587-97. PubMed ID: 12242656
[TBL] [Abstract][Full Text] [Related]
37. Synergistic interaction between 17-AAG and phosphatidylinositol 3-kinase inhibition in human malignant glioma cells.
Premkumar DR; Arnold B; Jane EP; Pollack IF
Mol Carcinog; 2006 Jan; 45(1):47-59. PubMed ID: 16267832
[TBL] [Abstract][Full Text] [Related]
38. The small-molecule Bcl-2 inhibitor HA14-1 interacts synergistically with flavopiridol to induce mitochondrial injury and apoptosis in human myeloma cells through a free radical-dependent and Jun NH2-terminal kinase-dependent mechanism.
Pei XY; Dai Y; Grant S
Mol Cancer Ther; 2004 Dec; 3(12):1513-24. PubMed ID: 15634644
[TBL] [Abstract][Full Text] [Related]
39. Blockage of cyclin cdk's, PKC and phosphoinositol 3-kinase pathways leads to augmentation of apoptosis in drug-resistant leukemia cells: evidence for interactive effects of flavopiridol, LY 294002, roscovitine,wortmannin and UCN-01.
Cory AH; Somerville L; Cory JG
Anticancer Res; 2005; 25(1A):101-6. PubMed ID: 15816525
[TBL] [Abstract][Full Text] [Related]
40. Insulin regulates cleavage of procaspase-9 via binding of X chromosome-linked inhibitor of apoptosis protein in HT-29 cells.
Kim JE; Tannenbaum SR
Cancer Res; 2004 Dec; 64(24):9070-5. PubMed ID: 15604274
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
