414 related articles for article (PubMed ID: 12706118)
1. Mutant p53 can delay growth arrest and loss of CDK2 activity in senescing human fibroblasts without reducing p21(WAF1) expression.
Wyllie F; Haughton M; Bartek J; Rowson J; Wynford-Thomas D
Exp Cell Res; 2003 May; 285(2):236-42. PubMed ID: 12706118
[TBL] [Abstract][Full Text] [Related]
2. Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts.
Dulić V; Beney GE; Frebourg G; Drullinger LF; Stein GH
Mol Cell Biol; 2000 Sep; 20(18):6741-54. PubMed ID: 10958672
[TBL] [Abstract][Full Text] [Related]
3. TGF-beta-mediated cell cycle arrest of HPV16-immortalized human ectocervical cells correlates with decreased E6/E7 mRNA and increased p53 and p21(WAF-1) expression.
Rorke EA; Zhang D; Choo CK; Eckert RL; Jacobberger JW
Exp Cell Res; 2000 Aug; 259(1):149-57. PubMed ID: 10942587
[TBL] [Abstract][Full Text] [Related]
4. Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts.
Stein GH; Drullinger LF; Soulard A; Dulić V
Mol Cell Biol; 1999 Mar; 19(3):2109-17. PubMed ID: 10022898
[TBL] [Abstract][Full Text] [Related]
5. Complex mechanisms underlying impaired activation of Cdk4 and Cdk2 in replicative senescence: roles of p16, p21, and cyclin D1.
Morisaki H; Ando A; Nagata Y; Pereira-Smith O; Smith JR; Ikeda K; Nakanishi M
Exp Cell Res; 1999 Dec; 253(2):503-10. PubMed ID: 10585273
[TBL] [Abstract][Full Text] [Related]
6. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
Rao S; Lowe M; Herliczek TW; Keyomarsi K
Oncogene; 1998 Nov; 17(18):2393-402. PubMed ID: 9811471
[TBL] [Abstract][Full Text] [Related]
7. Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells.
Sandhu C; Donovan J; Bhattacharya N; Stampfer M; Worland P; Slingerland J
Oncogene; 2000 Nov; 19(47):5314-23. PubMed ID: 11103932
[TBL] [Abstract][Full Text] [Related]
8. Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a).
Mitra J; Dai CY; Somasundaram K; El-Deiry WS; Satyamoorthy K; Herlyn M; Enders GH
Mol Cell Biol; 1999 May; 19(5):3916-28. PubMed ID: 10207115
[TBL] [Abstract][Full Text] [Related]
9. Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21Cip1 and p27Kip1 in anchorage-independent cells.
Orend G; Hunter T; Ruoslahti E
Oncogene; 1998 May; 16(20):2575-83. PubMed ID: 9632134
[TBL] [Abstract][Full Text] [Related]
10. Requirements for p53 and the ATM gene product in the regulation of G1/S and S phase checkpoints.
Xie G; Habbersett RC; Jia Y; Peterson SR; Lehnert BE; Bradbury EM; D'Anna JA
Oncogene; 1998 Feb; 16(6):721-36. PubMed ID: 9488036
[TBL] [Abstract][Full Text] [Related]
11. Induction of p21/WAF1 and G1 cell-cycle arrest by the chemopreventive agent apigenin.
Lepley DM; Pelling JC
Mol Carcinog; 1997 Jun; 19(2):74-82. PubMed ID: 9210954
[TBL] [Abstract][Full Text] [Related]
12. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
Akiyama T; Yoshida T; Tsujita T; Shimizu M; Mizukami T; Okabe M; Akinaga S
Cancer Res; 1997 Apr; 57(8):1495-501. PubMed ID: 9108451
[TBL] [Abstract][Full Text] [Related]
13. p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation.
Minella AC; Swanger J; Bryant E; Welcker M; Hwang H; Clurman BE
Curr Biol; 2002 Oct; 12(21):1817-27. PubMed ID: 12419181
[TBL] [Abstract][Full Text] [Related]
14. Induction of G1 phase arrest in MCF human breast cancer cells by pentagalloylglucose through the down-regulation of CDK4 and CDK2 activities and up-regulation of the CDK inhibitors p27(Kip) and p21(Cip).
Chen WJ; Chang CY; Lin JK
Biochem Pharmacol; 2003 Jun; 65(11):1777-85. PubMed ID: 12781329
[TBL] [Abstract][Full Text] [Related]
15. Initiation of DNA synthesis by human papillomavirus E7 oncoproteins is resistant to p21-mediated inhibition of cyclin E-cdk2 activity.
Ruesch MN; Laimins LA
J Virol; 1997 Jul; 71(7):5570-8. PubMed ID: 9188631
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of cell growth by transforming growth factor beta 1 is associated with p53-independent induction of p21 in gastric carcinoma cells.
Akagi M; Yasui W; Akama Y; Yokozaki H; Tahara H; Haruma K; Kajiyama G; Tahara E
Jpn J Cancer Res; 1996 Apr; 87(4):377-84. PubMed ID: 8641969
[TBL] [Abstract][Full Text] [Related]
17. Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells.
Jin YH; Yoo KJ; Lee YH; Lee SK
J Biol Chem; 2000 Sep; 275(39):30256-63. PubMed ID: 10884382
[TBL] [Abstract][Full Text] [Related]
18. Loss of G(1)/S checkpoint in human immunodeficiency virus type 1-infected cells is associated with a lack of cyclin-dependent kinase inhibitor p21/Waf1.
Clark E; Santiago F; Deng L; Chong S; de La Fuente C; Wang L; Fu P; Stein D; Denny T; Lanka V; Mozafari F; Okamoto T; Kashanchi F
J Virol; 2000 Jun; 74(11):5040-52. PubMed ID: 10799578
[TBL] [Abstract][Full Text] [Related]
19. Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation.
Baldassarre G; Barone MV; Belletti B; Sandomenico C; Bruni P; Spiezia S; Boccia A; Vento MT; Romano A; Pepe S; Fusco A; Viglietto G
Oncogene; 1999 Nov; 18(46):6241-51. PubMed ID: 10597222
[TBL] [Abstract][Full Text] [Related]
20. Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes.
Dulić V; Drullinger LF; Lees E; Reed SI; Stein GH
Proc Natl Acad Sci U S A; 1993 Dec; 90(23):11034-8. PubMed ID: 8248208
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]