BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

445 related articles for article (PubMed ID: 12706452)

  • 1. A phenylacetate derivative, SCK6, inhibits cell proliferation via G1 cell cycle arrest and apoptosis.
    Chan HC; Kuo SC; Huang LJ; Liu CH; Hsu SL
    Eur J Pharmacol; 2003 Apr; 467(1-3):31-9. PubMed ID: 12706452
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular mechanisms of ZD1839-induced G1-cell cycle arrest and apoptosis in human lung adenocarcinoma A549 cells.
    Chang GC; Hsu SL; Tsai JR; Liang FP; Lin SY; Sheu GT; Chen CY
    Biochem Pharmacol; 2004 Oct; 68(7):1453-64. PubMed ID: 15345335
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Berberine inhibits growth, induces G1 arrest and apoptosis in human epidermoid carcinoma A431 cells by regulating Cdki-Cdk-cyclin cascade, disruption of mitochondrial membrane potential and cleavage of caspase 3 and PARP.
    Mantena SK; Sharma SD; Katiyar SK
    Carcinogenesis; 2006 Oct; 27(10):2018-27. PubMed ID: 16621886
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resveratrol causes WAF-1/p21-mediated G(1)-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells.
    Ahmad N; Adhami VM; Afaq F; Feyes DK; Mukhtar H
    Clin Cancer Res; 2001 May; 7(5):1466-73. PubMed ID: 11350919
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Retinoic acid-mediated G1 arrest is associated with induction of p27(Kip1) and inhibition of cyclin-dependent kinase 3 in human lung squamous carcinoma CH27 cells.
    Hsu SL; Hsu JW; Liu MC; Chen LY; Chang CD
    Exp Cell Res; 2000 Aug; 258(2):322-31. PubMed ID: 10896783
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 4-Fluoro-N-butylphenylacetamide: a synthetic phenylacetate derivative that upregulates Bcl-X(S), activates caspase cascade and induces apoptosis in human squamous lung cancer CH27 cells.
    Chan HC; Kuo SC; Liu SC; Liu CH; Hsu SL
    Cancer Lett; 2002 Dec; 186(2):211-21. PubMed ID: 12213291
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phenoxodiol, a novel isoflavone, induces G1 arrest by specific loss in cyclin-dependent kinase 2 activity by p53-independent induction of p21WAF1/CIP1.
    Aguero MF; Facchinetti MM; Sheleg Z; Senderowicz AM
    Cancer Res; 2005 Apr; 65(8):3364-73. PubMed ID: 15833870
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Baicalein induced cell cycle arrest and apoptosis in human lung squamous carcinoma CH27 cells.
    Lee HZ; Leung HW; Lai MY; Wu CH
    Anticancer Res; 2005; 25(2A):959-64. PubMed ID: 15868934
    [TBL] [Abstract][Full Text] [Related]  

  • 9. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
    Akiyama T; Yoshida T; Tsujita T; Shimizu M; Mizukami T; Okabe M; Akinaga S
    Cancer Res; 1997 Apr; 57(8):1495-501. PubMed ID: 9108451
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Caspase-mediated Cdk2 activation is a critical step to execute transforming growth factor-beta1-induced apoptosis in human gastric cancer cells.
    Kim SG; Kim SN; Jong HS; Kim NK; Hong SH; Kim SJ; Bang YJ
    Oncogene; 2001 Mar; 20(10):1254-65. PubMed ID: 11313870
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
    Rao S; Lowe M; Herliczek TW; Keyomarsi K
    Oncogene; 1998 Nov; 17(18):2393-402. PubMed ID: 9811471
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effector mechanisms of norcantharidin-induced mitotic arrest and apoptosis in human hepatoma cells.
    Chen YN; Chen JC; Yin SC; Wang GS; Tsauer W; Hsu SF; Hsu SL
    Int J Cancer; 2002 Jul; 100(2):158-65. PubMed ID: 12115564
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tetrandrine induces early G1 arrest in human colon carcinoma cells by down-regulating the activity and inducing the degradation of G1-S-specific cyclin-dependent kinases and by inducing p53 and p21Cip1.
    Meng LH; Zhang H; Hayward L; Takemura H; Shao RG; Pommier Y
    Cancer Res; 2004 Dec; 64(24):9086-92. PubMed ID: 15604277
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).
    Patel V; Lahusen T; Leethanakul C; Igishi T; Kremer M; Quintanilla-Martinez L; Ensley JF; Sausville EA; Gutkind JS; Senderowicz AM
    Clin Cancer Res; 2002 Nov; 8(11):3549-60. PubMed ID: 12429646
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hepatitis B virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cells.
    Park US; Park SK; Lee YI; Park JG; Lee YI
    Oncogene; 2000 Jul; 19(30):3384-94. PubMed ID: 10918595
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of G1 phase arrest in MCF human breast cancer cells by pentagalloylglucose through the down-regulation of CDK4 and CDK2 activities and up-regulation of the CDK inhibitors p27(Kip) and p21(Cip).
    Chen WJ; Chang CY; Lin JK
    Biochem Pharmacol; 2003 Jun; 65(11):1777-85. PubMed ID: 12781329
    [TBL] [Abstract][Full Text] [Related]  

  • 17. F9 embryonal carcinoma cells fail to stop at G1/S boundary of the cell cycle after gamma-irradiation due to p21WAF1/CIP1 degradation.
    Malashicheva AB; Kislyakova TV; Aksenov ND; Osipov KA; Pospelov VA
    Oncogene; 2000 Aug; 19(34):3858-65. PubMed ID: 10951579
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells.
    Di Gennaro E; Barbarino M; Bruzzese F; De Lorenzo S; Caraglia M; Abbruzzese A; Avallone A; Comella P; Caponigro F; Pepe S; Budillon A
    J Cell Physiol; 2003 Apr; 195(1):139-50. PubMed ID: 12599217
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells.
    Jin YH; Yoo KJ; Lee YH; Lee SK
    J Biol Chem; 2000 Sep; 275(39):30256-63. PubMed ID: 10884382
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Grape seed proanthocyanidins promote apoptosis in human epidermoid carcinoma A431 cells through alterations in Cdki-Cdk-cyclin cascade, and caspase-3 activation via loss of mitochondrial membrane potential.
    Meeran SM; Katiyar SK
    Exp Dermatol; 2007 May; 16(5):405-15. PubMed ID: 17437483
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.