BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 12716462)

  • 1. The mouse rasH2/BHT model as an in vivo rapid assay for lung carcinogens.
    Umemura T; Kodama Y; Hioki K; Nomura T; Nishikawa A; Hirose M; Kurokawa Y
    Jpn J Cancer Res; 2002 Aug; 93(8):861-6. PubMed ID: 12716462
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Butylhydroxytoluene (BHT) increases susceptibility of transgenic rasH2 mice to lung carcinogenesis.
    Umemura T; Kodama Y; Hioki K; Inoue T; Nomura T; Kurokawa Y
    J Cancer Res Clin Oncol; 2001 Oct; 127(10):583-90. PubMed ID: 11599794
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model.
    Umemura T; Kodama Y; Nishikawa A; Hioki K; Nomura T; Kanki K; Kuroiwa Y; Ishii Y; Kurokawa Y; Hirose M
    Cancer Lett; 2006 Jan; 231(2):314-8. PubMed ID: 16399233
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Susceptibility to urethane carcinogenesis of transgenic mice carrying a human prototype c-Ha-ras gene (rasH2 mice) and its modification by butylhydroxytoluene.
    Umemura T; Kodama Y; Hioki K; Inoue T; Nomura T; Kurokawa Y
    Cancer Lett; 1999 Oct; 145(1-2):101-6. PubMed ID: 10530776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lack of modifying effects of eugenol on development of lung proliferative lesions induced by urethane in transgenic mice carrying the human prototype c-Ha-ras gene.
    Koujitani T; Yasuhara K; Tamura T; Onodera H; Takagi H; Takizawa T; Hirose M; Hayashi Y; Mitsumori K
    J Toxicol Sci; 2001 Aug; 26(3):129-39. PubMed ID: 11552296
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aberrant expression of cyclin D1 in pulmonary proliferative lesions induced by high doses of urethane in transgenic mice carrying the human prototype c-H-ras gene.
    Mori I; Yasuhara K; Hayashi SM; Nonoyama T; Nomura T; Yanai T; Masegi T; Mitsumori K
    J Vet Med Sci; 2001 Mar; 63(3):261-8. PubMed ID: 11307925
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Carcinogen dose-dependent variation in the transgene mutation spectrum in urethane-induced lung tumors in transgenic mice carrying the human prototype c-Ha-ras gene.
    Mori I; Yasuhara K; Hayashi SM; Nonoyama T; Nomura T; Mitsumori K
    Cancer Lett; 2000 May; 153(1-2):199-209. PubMed ID: 10779650
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pathological features of spontaneous and induced tumors in transgenic mice carrying a human prototype c-Ha-ras gene used for six-month carcinogenicity studies.
    Mitsumori K; Koizumi H; Nomura T; Yamamoto S
    Toxicol Pathol; 1998; 26(4):520-31. PubMed ID: 9715511
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Tg rasH2 mouse in cancer hazard identification.
    Morton D; Alden CL; Roth AJ; Usui T
    Toxicol Pathol; 2002; 30(1):139-46. PubMed ID: 11890467
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lack of susceptibility of transgenic mice carrying the human c-Ha-ras proto-oncogene (rasH2 mice) to phenolphthalein in a 6-month carcinogenicity study.
    Koujitani T; Yasuhara K; Usui T; Nomura T; Onodera H; Takagi H; Hirose M; Mitsumori K
    Cancer Lett; 2000 May; 152(2):211-6. PubMed ID: 10773414
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lung Tumor Induction by 26-week Dermal Application of 1,2-Dichloroethane in CB6F1-Tg rasH2 Mice.
    Suguro M; Numano T; Kawabe M; Doi Y; Imai N; Mera Y; Tamano S
    Toxicol Pathol; 2017 Apr; 45(3):427-434. PubMed ID: 28421967
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Validation of transgenic mice carrying the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing.
    Yamamoto S; Urano K; Koizumi H; Wakana S; Hioki K; Mitsumori K; Kurokawa Y; Hayashi Y; Nomura T
    Environ Health Perspect; 1998 Feb; 106 Suppl 1(Suppl 1):57-69. PubMed ID: 9539005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rapid induction of more malignant tumors by various genotoxic carcinogens in transgenic mice harboring a human prototype c-Ha-ras gene than in control non-transgenic mice.
    Yamamoto S; Mitsumori K; Kodama Y; Matsunuma N; Manabe S; Okamiya H; Suzuki H; Fukuda T; Sakamaki Y; Sunaga M; Nomura G; Hioki K; Wakana S; Nomura T; Hayashi Y
    Carcinogenesis; 1996 Nov; 17(11):2455-61. PubMed ID: 8968063
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pulmonary fibrosis caused by N-methyl-N-nitrosourethane inhibits lung tumorigenesis by urethane in transgenic mice carrying the human prototype c-Ha-ras gene.
    Mitsumori K; Yasuhara K; Mori I; Hayashi S; Shimo T; Onodera H; Nomura T; Hayashi Y
    Cancer Lett; 1998 Jul; 129(2):181-90. PubMed ID: 9719460
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Di(2-ethylhexyl)phthalate induces hepatocellular adenoma in transgenic mice carrying a human prototype c-Ha-ras gene in a 26-week carcinogenicity study.
    Toyosawa K; Okimoto K; Kobayashi I; Kijima K; Kikawa E; Kohchi M; Koujitani T; Tanaka K; Matsuoka N
    Toxicol Pathol; 2001; 29(4):458-66. PubMed ID: 11560251
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interlaboratory comparison of short-term carcinogenicity studies using CB6F1-rasH2 transgenic mice.
    Takaoka M; Sehata S; Maejima T; Imai T; Torii M; Satoh H; Toyosawa K; Tanakamaru ZY; Adachi T; Hisada S; Ueda M; Ogasawara H; Matsumoto M; Kobayashi K; Mutai M; Usui T
    Toxicol Pathol; 2003; 31(2):191-9. PubMed ID: 12696579
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proposal to Eliminate Urethane-Treated Positive Control Dose Groups in 26-Week Tg.rasH2 Carcinogenicity Studies.
    Paranjpe MG; Rudmann D; Sargeant A; Morse M; Yonpiam R; Bonnette K; Albretsen J; Papagiannis C
    Int J Toxicol; 2021; 40(3):207-210. PubMed ID: 33813924
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A metabolite of butylated hydroxytoluene with potent tumor-promoting activity in mouse lung.
    Thompson JA; Schullek KM; Fernandez CA; Malkinson AM
    Carcinogenesis; 1989 Apr; 10(4):773-5. PubMed ID: 2702725
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gene expression analysis in the lung of the rasH2 transgenic mouse at week 4 prior to induction of malignant tumor formation by urethane and N-methylolacrylamide.
    Tsuji S; Kuwahara Y; Takagi H; Sugiura M; Nakanishi Y; Wakamatsu M; Tsuritani K; Sato Y
    J Toxicol Sci; 2015 Dec; 40(6):685-700. PubMed ID: 26558449
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Studies using structural analogs and inbred strain differences to support a role for quinone methide metabolites of butylated hydroxytoluene (BHT) in mouse lung tumor promotion.
    Thompson JA; Carlson TJ; Sun Y; Dwyer-Nield LD; Malkinson AM
    Toxicology; 2001 Mar; 160(1-3):197-205. PubMed ID: 11246140
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.