BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

654 related articles for article (PubMed ID: 12717443)

  • 21. Calmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signaling.
    Villalonga P; López-Alcalá C; Bosch M; Chiloeches A; Rocamora N; Gil J; Marais R; Marshall CJ; Bachs O; Agell N
    Mol Cell Biol; 2001 Nov; 21(21):7345-54. PubMed ID: 11585916
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Sprouty4 negatively regulates protein kinase C activation by inhibiting phosphatidylinositol 4,5-biphosphate hydrolysis.
    Ayada T; Taniguchi K; Okamoto F; Kato R; Komune S; Takaesu G; Yoshimura A
    Oncogene; 2009 Feb; 28(8):1076-88. PubMed ID: 19137008
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Raf-1 kinase activation is uncoupled from downstream MEK/ERK pathway in cells treated with Src tyrosine kinase inhibitor PP2.
    Lee M
    Biochem Biophys Res Commun; 2006 Nov; 350(2):450-6. PubMed ID: 17010316
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions.
    Kolch W
    Biochem J; 2000 Oct; 351 Pt 2(Pt 2):289-305. PubMed ID: 11023813
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor.
    Easton JB; Royer AR; Middlemas DS
    J Neurochem; 2006 May; 97(3):834-45. PubMed ID: 16573649
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Growth factors differentially regulate neuronal Cav channels via ERK-dependent signalling.
    Woodall AJ; Richards MA; Turner DJ; Fitzgerald EM
    Cell Calcium; 2008 Jun; 43(6):562-75. PubMed ID: 17996937
    [TBL] [Abstract][Full Text] [Related]  

  • 27. SH2 domain containing protein tyrosine phosphatase 2 regulates concanavalin A-dependent secretion and activation of matrix metalloproteinase 2 via the extracellular signal-regulated kinase and p38 pathways.
    Ruhul Amin AR; Oo ML; Senga T; Suzuki N; Feng GS; Hamaguchi M
    Cancer Res; 2003 Oct; 63(19):6334-9. PubMed ID: 14559821
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Opposite role of Ras in tumor necrosis factor-alpha-induced cell cycle regulation: competition for Raf kinase.
    Park SJ; Kim YY; Lim JY; Seo GJ; Kim J; Park SI; Park BJ
    Biochem Biophys Res Commun; 2001 Oct; 287(5):1140-7. PubMed ID: 11587542
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Expression of the SNT-1/FRS2 phosphotyrosine binding domain inhibits activation of MAP kinase and PI3-kinase pathways and antiestrogen resistant growth induced by FGF-1 in human breast carcinoma cells.
    Manuvakhova M; Thottassery JV; Hays S; Qu Z; Rentz SS; Westbrook L; Kern FG
    Oncogene; 2006 Sep; 25(44):6003-14. PubMed ID: 16682955
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The EGF receptor activates ERK but not JNK Ras-dependently in basal conditions but ERK and JNK activation pathways are predominantly Ras-independent during cardiomyocyte stretch.
    Duquesnes N; Vincent F; Morel E; Lezoualc'h F; Crozatier B
    Int J Biochem Cell Biol; 2009 May; 41(5):1173-81. PubMed ID: 19015044
    [TBL] [Abstract][Full Text] [Related]  

  • 31. EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation.
    Reynolds AR; Tischer C; Verveer PJ; Rocks O; Bastiaens PI
    Nat Cell Biol; 2003 May; 5(5):447-53. PubMed ID: 12717446
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Flagellin and lipopolysaccharide stimulate the MEK-ERK signaling pathway in chicken heterophils through differential activation of the small GTPases, Ras and Rap1.
    Kogut MH; Genovese KJ; He H
    Mol Immunol; 2007 Mar; 44(7):1729-36. PubMed ID: 17045653
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Membrane recruitment of Raf-1 is not the only function of Ras in Raf-1 activation.
    Tamada M; Hu CD; Kariya K; Okada T; Kataoka T
    Oncogene; 1997 Dec; 15(24):2959-64. PubMed ID: 9416839
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling.
    Kiel C; Serrano L
    Sci Signal; 2009 Jul; 2(81):ra38. PubMed ID: 19638615
    [TBL] [Abstract][Full Text] [Related]  

  • 35. TC21 and Ras share indistinguishable transforming and differentiating activities.
    Graham SM; Oldham SM; Martin CB; Drugan JK; Zohn IE; Campbell S; Der CJ
    Oncogene; 1999 Mar; 18(12):2107-16. PubMed ID: 10321735
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR).
    Zhou M; Horita DA; Waugh DS; Byrd RA; Morrison DK
    J Mol Biol; 2002 Jan; 315(3):435-46. PubMed ID: 11786023
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Tyrosines 303/343/353 within the Sprouty-related domain of Spred2 are essential for its interaction with p85 and inhibitory effect on Ras/ERK activation.
    Meng S; Zhang M; Pan W; Li Z; Anderson DH; Zhang S; Ge B; Wang C
    Int J Biochem Cell Biol; 2012 May; 44(5):748-58. PubMed ID: 22305891
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Regulation of extracellular signal-regulated kinase activity by p120 RasGAP does not involve its pleckstrin homology or calcium-dependent lipid binding domains but does require these domains to regulate cell proliferation.
    Koehler JA; Moran MF
    Cell Growth Differ; 2001 Nov; 12(11):551-61. PubMed ID: 11714636
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway (Review).
    Chang F; Steelman LS; Shelton JG; Lee JT; Navolanic PM; Blalock WL; Franklin R; McCubrey JA
    Int J Oncol; 2003 Mar; 22(3):469-80. PubMed ID: 12579299
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation.
    Satyamoorthy K; Li G; Gerrero MR; Brose MS; Volpe P; Weber BL; Van Belle P; Elder DE; Herlyn M
    Cancer Res; 2003 Feb; 63(4):756-9. PubMed ID: 12591721
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 33.