BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

382 related articles for article (PubMed ID: 12724322)

  • 1. Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4.
    Jefferies CA; Doyle S; Brunner C; Dunne A; Brint E; Wietek C; Walch E; Wirth T; O'Neill LA
    J Biol Chem; 2003 Jul; 278(28):26258-64. PubMed ID: 12724322
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.
    Gray P; Dunne A; Brikos C; Jefferies CA; Doyle SL; O'Neill LA
    J Biol Chem; 2006 Apr; 281(15):10489-95. PubMed ID: 16439361
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide.
    Doyle SL; Jefferies CA; O'Neill LA
    J Biol Chem; 2005 Jun; 280(25):23496-501. PubMed ID: 15849198
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bruton's tyrosine kinase (Btk)-the critical tyrosine kinase in LPS signalling?
    Jefferies CA; O'Neill LA
    Immunol Lett; 2004 Mar; 92(1-2):15-22. PubMed ID: 15081522
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells.
    Li X; Tupper JC; Bannerman DD; Winn RK; Rhodes CJ; Harlan JM
    Infect Immun; 2003 Aug; 71(8):4414-20. PubMed ID: 12874320
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
    Fitzgerald KA; Palsson-McDermott EM; Bowie AG; Jefferies CA; Mansell AS; Brady G; Brint E; Dunne A; Gray P; Harte MT; McMurray D; Smith DE; Sims JE; Bird TA; O'Neill LA
    Nature; 2001 Sep; 413(6851):78-83. PubMed ID: 11544529
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.
    Oshiumi H; Sasai M; Shida K; Fujita T; Matsumoto M; Seya T
    J Biol Chem; 2003 Dec; 278(50):49751-62. PubMed ID: 14519765
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1.
    Yang H; Young DW; Gusovsky F; Chow JC
    J Biol Chem; 2000 Jul; 275(27):20861-6. PubMed ID: 10877845
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bruton's tyrosine kinase is required for TLR-dependent heme oxygenase-1 gene activation via Nrf2 in macrophages.
    Vijayan V; Baumgart-Vogt E; Naidu S; Qian G; Immenschuh S
    J Immunol; 2011 Jul; 187(2):817-27. PubMed ID: 21677132
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance.
    Piao W; Song C; Chen H; Wahl LM; Fitzgerald KA; O'Neill LA; Medvedev AE
    J Biol Chem; 2008 Feb; 283(6):3109-3119. PubMed ID: 18070880
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Specific binding of the WASP N-terminal domain to Btk is critical for TLR2 signaling in macrophages.
    Sakuma C; Sato M; Takenouchi T; Kitani H
    Mol Immunol; 2015 Feb; 63(2):328-36. PubMed ID: 25213142
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4.
    Mansell A; Brint E; Gould JA; O'Neill LA; Hertzog PJ
    J Biol Chem; 2004 Sep; 279(36):37227-30. PubMed ID: 15247281
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of bacterial lipoprotein tolerance is associated with suppression of toll-like receptor 2 expression.
    Wang JH; Doyle M; Manning BJ; Di Wu Q; Blankson S; Redmond HP
    J Biol Chem; 2002 Sep; 277(39):36068-75. PubMed ID: 12133836
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP.
    Andreakos E; Sacre SM; Smith C; Lundberg A; Kiriakidis S; Stonehouse T; Monaco C; Feldmann M; Foxwell BM
    Blood; 2004 Mar; 103(6):2229-37. PubMed ID: 14630816
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase.
    Rhee SH; Hwang D
    J Biol Chem; 2000 Nov; 275(44):34035-40. PubMed ID: 10952994
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors.
    DiPerna G; Stack J; Bowie AG; Boyd A; Kotwal G; Zhang Z; Arvikar S; Latz E; Fitzgerald KA; Marshall WL
    J Biol Chem; 2004 Aug; 279(35):36570-8. PubMed ID: 15215253
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms.
    Qin J; Qian Y; Yao J; Grace C; Li X
    J Biol Chem; 2005 Jul; 280(26):25233-41. PubMed ID: 15866876
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase.
    Doyle SL; Jefferies CA; Feighery C; O'Neill LA
    J Biol Chem; 2007 Dec; 282(51):36953-60. PubMed ID: 17932028
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment.
    Page TH; Urbaniak AM; Espirito Santo AI; Danks L; Smallie T; Williams LM; Horwood NJ
    Biochem Biophys Res Commun; 2018 May; 499(2):260-266. PubMed ID: 29567473
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Toll-like receptor 4-, 7-, and 8-activated myeloid cells from patients with X-linked agammaglobulinemia produce enhanced inflammatory cytokines.
    Marron TU; Martinez-Gallo M; Yu JE; Cunningham-Rundles C
    J Allergy Clin Immunol; 2012 Jan; 129(1):184-90.e1-4. PubMed ID: 22088613
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.