BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

108 related articles for article (PubMed ID: 12729655)

  • 1. Structure-activity relationship of a novel class of naphthyl amide KATP channel openers.
    Turner SC; Carroll WA; White TK; Brune ME; Buckner SA; Gopalakrishnan M; Fabiyi A; Coghlan MJ; Scott VE; Castle NA; Daza AV; Milicic I; Sullivan JP
    Bioorg Med Chem Lett; 2003 May; 13(10):1741-4. PubMed ID: 12729655
    [TBL] [Abstract][Full Text] [Related]  

  • 2. (-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637): a novel ATP-sensitive potassium channel opener efficacious in suppressing urinary bladder contractions. I. In vitro characterization.
    Gopalakrishnan M; Buckner SA; Whiteaker KL; Shieh CC; Molinari EJ; Milicic I; Daza AV; Davis-Taber R; Scott VE; Sellers D; Chess-Williams R; Chapple CR; Liu Y; Liu D; Brioni JD; Sullivan JP; Williams M; Carroll WA; Coghlan MJ
    J Pharmacol Exp Ther; 2002 Oct; 303(1):379-86. PubMed ID: 12235274
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of human urinary bladder KATP channels containing SUR2B splice variants expressed in L-cells.
    Scott VE; Davis-Taber RA; Silvia C; Hoogenboom L; Choi W; Kroeger P; Whiteaker KL; Gopalakrishnan M
    Eur J Pharmacol; 2004 Jan; 483(2-3):195-205. PubMed ID: 14729107
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro and in vivo characterization of a novel naphthylamide ATP-sensitive K+ channel opener, A-151892.
    Gopalakrishnan M; Buckner SA; Shieh CC; Fey T; Fabiyi A; Whiteaker KL; Davis-Taber R; Milicic I; Daza AV; Scott VE; Castle NA; Printzenhoff D; London B; Turner SC; Carroll WA; Sullivan JP; Coghlan MJ; Brune ME
    Br J Pharmacol; 2004 Sep; 143(1):81-90. PubMed ID: 15302680
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of K(ATP)-channels in rat basilar and middle cerebral arteries: studies of vasomotor responses and mRNA expression.
    Jansen-Olesen I; Mortensen CH; El-Bariaki N; Ploug KB
    Eur J Pharmacol; 2005 Oct; 523(1-3):109-18. PubMed ID: 16226739
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interaction of a novel dihydropyridine K+ channel opener, A-312110, with recombinant sulphonylurea receptors and KATP channels: comparison with the cyanoguanidine P1075.
    Felsch H; Lange U; Hambrock A; Löffler-Walz C; Russ U; Carroll WA; Gopalakrishnan M; Quast U
    Br J Pharmacol; 2004 Apr; 141(7):1098-105. PubMed ID: 15023854
    [TBL] [Abstract][Full Text] [Related]  

  • 7. (-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637): a novel ATP-sensitive potassium channel opener efficacious in suppressing urinary bladder contractions. II. in vivo characterization.
    Brune ME; Fey TA; Brioni JD; Sullivan JP; Williams M; Carroll WA; Coghlan MJ; Gopalakrishnan M
    J Pharmacol Exp Ther; 2002 Oct; 303(1):387-94. PubMed ID: 12235275
    [TBL] [Abstract][Full Text] [Related]  

  • 8. K-ATP opener-mediated attenuation of spontaneous bladder contractions in ligature-intact, partial bladder outlet obstructed rats.
    Lynch JJ; Brune ME; Lubbers NL; Coghlan MJ; Cox BF; Polakowski JS; King LL; Sullivan JP; Brioni JD
    Life Sci; 2003 Mar; 72(17):1931-41. PubMed ID: 12597992
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A key role for the subunit SUR2B in the preferential activation of vascular KATP channels by isoflurane.
    Fujita H; Ogura T; Tamagawa M; Uemura H; Sato T; Ishida A; Imamaki M; Kimura F; Miyazaki M; Nakaya H
    Br J Pharmacol; 2006 Nov; 149(5):573-80. PubMed ID: 17001304
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potassium channel openers require ATP to bind to and act through sulfonylurea receptors.
    Schwanstecher M; Sieverding C; Dörschner H; Gross I; Aguilar-Bryan L; Schwanstecher C; Bryan J
    EMBO J; 1998 Oct; 17(19):5529-35. PubMed ID: 9755153
    [TBL] [Abstract][Full Text] [Related]  

  • 11. KCO912: a potent and selective opener of ATP-dependent potassium (K(ATP)) channels which suppresses airways hyperreactivity at doses devoid of cardiovascular effects.
    Buchheit KH; Manley PW; Quast U; Russ U; Mazzoni L; Fozard JR
    Naunyn Schmiedebergs Arch Pharmacol; 2002 Mar; 365(3):220-30. PubMed ID: 11882918
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Remodelling of the SUR-Kir6.2 interface of the KATP channel upon ATP binding revealed by the conformational blocker rhodamine 123.
    Hosy E; Dérand R; Revilloud J; Vivaudou M
    J Physiol; 2007 Jul; 582(Pt 1):27-39. PubMed ID: 17510180
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Arylcyanoguanidines as activators of Kir6.2/SUR1K ATP channels and inhibitors of insulin release.
    Tagmose TM; Schou SC; Mogensen JP; Nielsen FE; Arkhammar PO; Wahl P; Hansen BS; Worsaae A; Boonen HC; Antoine MH; Lebrun P; Hansen JB
    J Med Chem; 2004 Jun; 47(12):3202-11. PubMed ID: 15163199
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of a novel ATP-sensitive K+ channel opener, A-251179, on urinary bladder relaxation and cystometric parameters.
    Shieh CC; Brune ME; Buckner SA; Whiteaker KL; Molinari EJ; Milicic IA; Fabiyi AC; Daza A; Brioni JD; Carroll WA; Matsushita K; Yamada M; Kurachi Y; Gopalakrishnan M
    Br J Pharmacol; 2007 Jun; 151(4):467-75. PubMed ID: 17435796
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and SAR of novel potassium channel openers targeted for urge urinary incontinence. 1. N-Cyanoguanidine bioisosteres possessing in vivo bladder selectivity.
    Butera JA; Antane MM; Antane SA; Argentieri TM; Freeden C; Graceffa RF; Hirth BH; Jenkins D; Lennox JR; Matelan E; Norton NW; Quagliato D; Sheldon JH; Spinelli W; Warga D; Wojdan A; Woods M
    J Med Chem; 2000 Mar; 43(6):1187-202. PubMed ID: 10737752
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Different molecular sites of action for the KATP channel inhibitors, PNU-99963 and PNU-37883A.
    Cui Y; Tinker A; Clapp LH
    Br J Pharmacol; 2003 May; 139(1):122-8. PubMed ID: 12746230
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives potently and selectively activate ATP sensitive potassium channels of pancreatic beta-cells.
    Nielsen FE; Bodvarsdottir TB; Worsaae A; MacKay P; Stidsen CE; Boonen HC; Pridal L; Arkhammar PO; Wahl P; Ynddal L; Junager F; Dragsted N; Tagmose TM; Mogensen JP; Koch A; Treppendahl SP; Hansen JB
    J Med Chem; 2002 Sep; 45(19):4171-87. PubMed ID: 12213059
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and characterization of a novel tritiated KATP channel opener with a benzopyran structure.
    Manley PW; Löffler-Walz C; Russ U; Hambrock A; Moenius T; Quast U
    Br J Pharmacol; 2001 May; 133(2):275-85. PubMed ID: 11350864
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Putative subunits of the rat mesangial KATP: a type 2B sulfonylurea receptor and an inwardly rectifying K+ channel.
    Szamosfalvi B; Cortes P; Alviani R; Asano K; Riser BL; Zasuwa G; Yee J
    Kidney Int; 2002 May; 61(5):1739-49. PubMed ID: 11967023
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein kinase C modulation of recombinant ATP-sensitive K(+) channels composed of Kir6.1 and/or Kir6.2 expressed with SUR2B.
    Thorneloe KS; Maruyama Y; Malcolm AT; Light PE; Walsh MP; Cole WC
    J Physiol; 2002 May; 541(Pt 1):65-80. PubMed ID: 12015420
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.