These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

107 related articles for article (PubMed ID: 12729659)

  • 1. 4-(3,4-dihydro-1H-isoquinolin-2yl)-pyridines and 4-(3,4-dihydro-1H-isoquinolin-2-yl)-quinolines as potent NR1/2B subtype selective NMDA receptor antagonists.
    Büttelmann B; Alanine A; Bourson A; Gill R; Heitz MP; Mutel V; Pinard E; Trube G; Wyler R
    Bioorg Med Chem Lett; 2003 May; 13(10):1759-62. PubMed ID: 12729659
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2-(3,4-Dihydro-1H-isoquinolin-2yl)-pyridines as a novel class of NR1/2B subtype selective NMDA receptor antagonists.
    Büttelmann B; Alanine A; Bourson A; Gill R; Heitz MP; Mutel V; Pinard E; Trube G; Wyler R
    Bioorg Med Chem Lett; 2003 Mar; 13(5):829-32. PubMed ID: 12617901
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 1-Benzyloxy-4,5-dihydro-1H-imidazol-2-yl-amines, a novel class of NR1/2B subtype selective NMDA receptor antagonists.
    Alanine A; Bourson A; Büttelmann B; Gill R; Heitz MP; Mutel V; Pinard E; Trube G; Wyler R
    Bioorg Med Chem Lett; 2003 Oct; 13(19):3155-9. PubMed ID: 12951084
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationship for a series of 2-substituted 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indoles: potent subtype-selective inhibitors of N-methyl-D-aspartate (NMDA) receptors.
    Tamiz AP; Whittemore ER; Woodward RM; Upasani RB; Keana JF
    Bioorg Med Chem Lett; 1999 Jun; 9(11):1619-24. PubMed ID: 10386947
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pyridazinoquinolinetriones as NMDA glycine-site antagonists with oral antinociceptive activity in a model of neuropathic pain.
    Bare TM; Brown DG; Horchler CL; Murphy M; Urbanek RA; Alford V; Barlaam C; Dyroff MC; Empfield JB; Forst JM; Herzog KJ; Keith RA; Kirschner AS; Lee CM; Lewis J; McLaren FM; Neilson KL; Steelman GB; Trivedi S; Vacek EP; Xiao W
    J Med Chem; 2007 Jun; 50(13):3113-31. PubMed ID: 17542571
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.
    Baraldi PG; Tabrizi MA; Preti D; Bovero A; Romagnoli R; Fruttarolo F; Zaid NA; Moorman AR; Varani K; Gessi S; Merighi S; Borea PA
    J Med Chem; 2004 Mar; 47(6):1434-47. PubMed ID: 14998332
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 4-Aminoquinolines as a novel class of NR1/2B subtype selective NMDA receptor antagonists.
    Pinard E; Alanine A; Bourson A; Büttelmann B; Heitz M; Mutela Ramanjit Gill V; Trube G; Wyler R
    Bioorg Med Chem Lett; 2002 Sep; 12(18):2615-9. PubMed ID: 12182873
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Two intermediates in the synthesis of decahydroisoquinolines with NMDA and AMPA receptor antagonist activity.
    Zukerman-Schpector J; Vega M; Caracelli I; Dias LC; Fernandes AM
    Acta Crystallogr C; 2001 Sep; 57(Pt 9):1089-91. PubMed ID: 11588380
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of 7-chloro-2,3-dihydro-2-[1-(pyridinyl)alkyl]-pyridazino[4,5-b]quinoline-1,4,10(5H)-triones as NMDA glycine-site antagonists.
    Brown DG; Urbanek RA; Bare TM; McLaren FM; Horchler CL; Murphy M; Steelman GB; Empfield JR; Forst JM; Herzog KJ; Xiao W; Dyroff MC; Lee CM; Trivedi S; Neilson KL; Keith RA
    Bioorg Med Chem Lett; 2003 Oct; 13(20):3553-6. PubMed ID: 14505669
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action.
    Kleckner NW; Glazewski JC; Chen CC; Moscrip TD
    J Pharmacol Exp Ther; 1999 May; 289(2):886-94. PubMed ID: 10215667
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of 3,5-dihydro-2-aryl-1H-pyrazolo[3,4-c]quinoline-1,4(2H)-diones as novel high-affinity glycine site N-methyl-D-aspartate antagonists.
    MacLeod AM; Grimwood S; Barton C; Bristow L; Saywell KL; Marshall GR; Ball RG
    J Med Chem; 1995 Jun; 38(12):2239-43. PubMed ID: 7783155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel structure having antagonist actions at both the glycine site of the N-methyl-D-aspartate receptor and neuronal voltage-sensitive sodium channels: biochemical, electrophysiological, and behavioral characterization.
    Snell LD; Claffey DJ; Ruth JA; Valenzuela CF; Cardoso R; Wang Z; Levinson SR; Sather WA; Williamson AV; Ingersoll NC; Ovchinnikova L; Bhave SV; Hoffman PL; Tabakoff B
    J Pharmacol Exp Ther; 2000 Jan; 292(1):215-27. PubMed ID: 10604951
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and structure-activity relationships of 1,2,3,4-tetrahydroquinoline-2,3,4-trione 3-oximes: novel and highly potent antagonists for NMDA receptor glycine site.
    Cai SX; Zhou ZL; Huang JC; Whittemore ER; Egbuwoku ZO; Lü Y; Hawkinson JE; Woodward RM; Weber E; Keana JF
    J Med Chem; 1996 Aug; 39(17):3248-55. PubMed ID: 8765507
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationships of 1,4-dihydro-(1H,4H)-quinoxaline-2,3-diones as N-methyl-D-aspartate (glycine site) receptor antagonists. 1. Heterocyclic substituted 5-alkyl derivatives.
    Fray MJ; Bull DJ; Carr CL; Gautier EC; Mowbray CE; Stobie A
    J Med Chem; 2001 Jun; 44(12):1951-62. PubMed ID: 11384240
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1H-Imidazo[4,5-c]quinoline derivatives as novel potent TNF-alpha suppressors: synthesis and structure-activity relationship of 1-, 2-and 4-substituted 1H-imidazo[4,5-c]quinolines or 1H-imidazo[4,5-c]pyridines.
    Izumi T; Sakaguchi J; Takeshita M; Tawara H; Kato K; Dose H; Tsujino T; Watanabe Y; Kato H
    Bioorg Med Chem; 2003 Jun; 11(12):2541-50. PubMed ID: 12757722
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and anticonvulsant activity of 7-alkoxyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolines.
    Xie ZF; Chai KY; Piao HR; Kwak KC; Quan ZS
    Bioorg Med Chem Lett; 2005 Nov; 15(21):4803-5. PubMed ID: 16139502
    [TBL] [Abstract][Full Text] [Related]  

  • 17. State-dependent NMDA receptor antagonism by Ro 8-4304, a novel NR2B selective, non-competitive, voltage-independent antagonist.
    Kew JN; Trube G; Kemp JA
    Br J Pharmacol; 1998 Feb; 123(3):463-72. PubMed ID: 9504387
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-activity analysis of a novel NR2C/NR2D-preferring NMDA receptor antagonist: 1-(phenanthrene-2-carbonyl) piperazine-2,3-dicarboxylic acid.
    Feng B; Tse HW; Skifter DA; Morley R; Jane DE; Monaghan DT
    Br J Pharmacol; 2004 Feb; 141(3):508-16. PubMed ID: 14718249
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of novel and orally active NR2B-selective N-methyl-D-aspartate (NMDA) antagonists, pyridinol derivatives with reduced HERG binding affinity.
    Kawai M; Nakamura H; Sakurada I; Shimokawa H; Tanaka H; Matsumizu M; Ando K; Hattori K; Ohta A; Nukui S; Omura A; Kawamura M
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5533-6. PubMed ID: 17768047
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and structure--activity relationships of fused imidazopyridines: a new series of benzodiazepine receptor ligands.
    Takada S; Sasatani T; Chomei N; Adachi M; Fujishita T; Eigyo M; Murata S; Kawasaki K; Matsushita A
    J Med Chem; 1996 Jul; 39(14):2844-51. PubMed ID: 8709114
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.