These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 12729741)

  • 1. Systematic variation of amino acid substitutions for stringent assessment of pairwise covariation.
    Govindarajan S; Ness JE; Kim S; Mundorff EC; Minshull J; Gustafsson C
    J Mol Biol; 2003 May; 328(5):1061-9. PubMed ID: 12729741
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of covariation in an SH3 domain sequence alignment: applications in tertiary contact prediction and the design of compensating hydrophobic core substitutions.
    Larson SM; Di Nardo AA; Davidson AR
    J Mol Biol; 2000 Oct; 303(3):433-46. PubMed ID: 11031119
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stabilizing the subtilisin BPN' pro-domain by phage display selection: how restrictive is the amino acid code for maximum protein stability?
    Ruan B; Hoskins J; Wang L; Bryan PN
    Protein Sci; 1998 Nov; 7(11):2345-53. PubMed ID: 9828000
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel oxidatively stable subtilisin-like serine proteases from alkaliphilic Bacillus spp.: enzymatic properties, sequences, and evolutionary relationships.
    Saeki K; Okuda M; Hatada Y; Kobayashi T; Ito S; Takami H; Horikoshi K
    Biochem Biophys Res Commun; 2000 Dec; 279(2):313-9. PubMed ID: 11118284
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural changes leading to increased enzymatic activity in an engineered variant of Bacillus lentus subtilisin.
    Bott R; Dauberman J; Wilson L; Ganshaw G; Sagar H; Graycar T; Estell D
    Adv Exp Med Biol; 1996; 379():277-83. PubMed ID: 8796332
    [No Abstract]   [Full Text] [Related]  

  • 6. Detecting compensatory covariation signals in protein evolution using reconstructed ancestral sequences.
    Fukami-Kobayashi K; Schreiber DR; Benner SA
    J Mol Biol; 2002 Jun; 319(3):729-43. PubMed ID: 12054866
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Directed evolution study of temperature adaptation in a psychrophilic enzyme.
    Miyazaki K; Wintrode PL; Grayling RA; Rubingh DN; Arnold FH
    J Mol Biol; 2000 Apr; 297(4):1015-26. PubMed ID: 10736234
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substrate specificity of natural variants and genetically engineered intermediates of Bacillus lentus alkaline proteases.
    Maurer KH; Markgraf M; Goddette D
    Adv Exp Med Biol; 1996; 379():243-56. PubMed ID: 8796329
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Engineering a novel specificity in subtilisin BPN'.
    Rheinnecker M; Baker G; Eder J; Fersht AR
    Biochemistry; 1993 Feb; 32(5):1199-203. PubMed ID: 8448130
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Intramolecular allosteric communication in dopamine D2 receptor revealed by evolutionary amino acid covariation.
    Sung YM; Wilkins AD; Rodriguez GJ; Wensel TG; Lichtarge O
    Proc Natl Acad Sci U S A; 2016 Mar; 113(13):3539-44. PubMed ID: 26979958
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinguishing functional amino acid covariation from background linkage disequilibrium in HIV protease and reverse transcriptase.
    Wang Q; Lee C
    PLoS One; 2007 Aug; 2(8):e814. PubMed ID: 17726544
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Directed evolution improves the fibrinolytic activity of nattokinase from Bacillus natto.
    Yongjun C; Wei B; Shujun J; Meizhi W; Yan J; Yan Y; Zhongliang Z; Goulin Z
    FEMS Microbiol Lett; 2011 Dec; 325(2):155-61. PubMed ID: 22029857
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The effect of amino acid deletion in subtilisin E, based on structural comparison with a microbial alkaline elastase, on its substrate specificity and catalysis.
    Takagi H; Arafuka S; Inouye M; Yamasaki M
    J Biochem; 1992 May; 111(5):584-8. PubMed ID: 1639753
    [TBL] [Abstract][Full Text] [Related]  

  • 14. High-resolution crystal structure of M-protease: phylogeny aided analysis of the high-alkaline adaptation mechanism.
    Shirai T; Suzuki A; Yamane T; Ashida T; Kobayashi T; Hitomi J; Ito S
    Protein Eng; 1997 Jun; 10(6):627-34. PubMed ID: 9278275
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A new subtilisin family: nucleotide and deduced amino acid sequences of new high-molecular-mass alkaline proteases from Bacillus spp.
    Okuda M; Sumitomo N; Takimura Y; Ogawa A; Saeki K; Kawai S; Kobayashi T; Ito S
    Extremophiles; 2004 Jun; 8(3):229-35. PubMed ID: 15022105
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Calcium-mediated thermostability in the subtilisin superfamily: the crystal structure of Bacillus Ak.1 protease at 1.8 A resolution.
    Smith CA; Toogood HS; Baker HM; Daniel RM; Baker EN
    J Mol Biol; 1999 Dec; 294(4):1027-40. PubMed ID: 10588904
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Significance of hydrophobic S4-P4 interactions in subtilisin 309 from Bacillus lentus.
    Bech LM; Sørensen SB; Breddam K
    Biochemistry; 1993 Mar; 32(11):2845-52. PubMed ID: 8457550
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reconstructing the diversification of subtilisins in the pathogenic fungus Metarhizium anisopliae.
    Bagga S; Hu G; Screen SE; St Leger RJ
    Gene; 2004 Jan; 324():159-69. PubMed ID: 14693381
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative analysis of sequence covariation methods to mine evolutionary hubs: examples from selected GPCR families.
    Pelé J; Moreau M; Abdi H; Rodien P; Castel H; Chabbert M
    Proteins; 2014 Sep; 82(9):2141-56. PubMed ID: 24677372
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tuning the activity of an enzyme for unusual environments: sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide.
    Chen K; Arnold FH
    Proc Natl Acad Sci U S A; 1993 Jun; 90(12):5618-22. PubMed ID: 8516309
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.